AstraZeneca

Lead regional site strategy, activation, and clinical workflows for cell therapy trials while ensuring quality and compliance and coordinating logistics and cross-functional teams. | Requires a bachelor's degree, at least 8 years of clinical experience, and expertise in cell therapy standards, regulatory frameworks, and project management, with a strong preference for 6 years of CAR-T experience. | Associate Director, Territory Operations Manager – Cell Therapy - Northwest Region Are you ready to pioneer cell therapy trial operations across a dynamic region and help transform outcomes for people with cancer? This role sits at the intersection of science, operations, and patient care—where robust clinical execution and smart, data-informed decisions accelerate both trials and future commercial delivery. As a regional expert, you will guide treatment centers through complex cell therapy workflows, from site strategy and activation to ongoing operational and clinical oversight. You will connect frontline teams with internal experts, turning standards into daily practice and removing barriers that slow patient access. Can you envision yourself setting the pace for how advanced therapies are introduced and sustained across multiple sites? This is a remote, regional role reporting to a Regional Operations Director and partnering closely with cross-functional leaders to build scalable, patient-centered service lines that uphold the highest quality and compliance standards. Responsibilities: Regional Site Strategy: Partner with regional leadership to shape site selection and expansion plans that accelerate patient access and trial readiness while ensuring sustainable operations. Site Activation and Certification: Lead risk-based activation, certification, and training programs to bring new treatment centers online efficiently and compliantly. Clinical Workflow Excellence: Guide end-to-end cell therapy workflows—including apheresis, product handling, infusion, and documentation—to deliver consistent, high-quality patient care. Quality and Compliance Leadership: Operate within relevant regulatory and accreditation frameworks (e.g., FACT), driving audit readiness, deviation management, CAPA execution, and continuous improvement. Cross-Functional Leadership: Align with Program Management, Manufacturing, Supply Chain, Quality, Medical, Market Access, Compliance, and Commercial to ensure integrated delivery across clinical and commercial phases. Collaborator Engagement: Build positive relationships with investigators, physicians, nurses, apheresis teams, cell therapy labs, and site leadership to establish patient-centered service lines. Logistics and Supply Chain Coordination: Act as the primary operations readiness liaison, aligning site needs with supply chain timelines, COI/COC processes, and regional account changes. Training and Mentorship: Design and deliver training for site staff and junior team members to elevate capability and consistency across the region. Issue Management and Continuous Improvement: Respond constructively to SOP deviations, implement corrective actions, and share guidelines to strengthen system-wide performance. Reporting and Insights: Lead research and internal reporting on standards, performance, and guidelines to inform governance and strategy across multiple countries and local contexts. Travel: Travel up to 50% to engage with sites, support activations, and maintain ongoing operational oversight. Essential Requirements: Bachelor’s degree or equivalent experience with detailed knowledge/hands-on experience in Cell Therapy (preferred: nursing, Life Sciences, healthcare administration, Business). 8 years of clinical experience within a hospital setting and/or industry, with 6 years of CAR-T experience preferred. Expertise in service lines (infrastructure, resourcing, costs, quality metrics). Proven delivery to timelines, cost, and quality; collaboration with internal/external providers. Excellent knowledge of cell therapy standards/regulations. Experience selecting/overseeing external providers and developing contracts. Essential Requirements: Advanced scientific degree or equivalent experience; broad understanding across patient operations, manufacturing interfaces, quality, regulatory, market access; project management experience. Program/Quality qualifications (e.g., PMP, CPHQ). Experience across academic/Sponsor settings and countries. Early-phase delivery across product lifecycle and multiple therapeutic areas. Salesforce or similar CRM experience. The annual base pay (or hourly rate of compensation) for this position ranges from $150,098 - $225,147 USD. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. Date Posted 20-Oct-2026 Closing Date 02-Nov-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

Lead regional customer directors to build key external expert advocacy, generate brand insights, and execute congress strategies across the Immunology portfolio. | Requires a bachelor's degree and 10+ years in pharmaceutical or biotech roles across multiple commercial functions, with leadership and preferably Immunology clinical experience. | At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person. The Senior Director, Regional Customer Team, leads the Regional Customer Director team responsible for identifying & developing KEE advocacy, generating disease and brand specific insights, co-leading national/regional/local congresses, identifying and coaching a team to support the development of brand speakers and leading advisory boards across the Immunology portfolio. This role reports to the US Head of Immunology and sits on the US Immunology Commercial leadership team to build the strategy for USCom and leads the Regional Customer Directors in working with multiple stakeholders and partners at headquarters, including the Brand team, Sales, Market Access, and Medical Affairs. Collaborating nationally as well as at the area and regional level, the Senior Director identifies and develops current and future Key External Experts (KEE) in CVRM for activities based on commercial value, driving greater engagement and advocacy while informing insights and brand strategy for the CVRM franchise. What you'll do Provide strategic direction to the team of Regional Customer Directors and Co- Develop the Clinical to Commercial HCP Scientific Communications platform with our Medical and US Marketing team. Build the KEE engagement Strategy and lead the development of the cross functional KEE Advocacy Plan for US KEEs. Ensure a robust depth of connection with Immunology Commercial Key External Expert relationships at the national, regional, and area level. Proactively identify opportunities in the identification and development of future KEEs and influencers (up-and-comers). Co-develop the National Congress strategy for Immunology with the marketing team and oversee all KEE engagement at Congresses. Ensure Regional plans are developed, compliant, and aligned with the Medical, Marketing, and Sales strategies for the brands, including product theaters, speaker programs, booths, and ESE interactions. Utilize input from KEEs to help build market leadership, advocacy, and commercial strategies through appropriate tactics such as Ad Boards, Virtual Community, Expert Panels, Speaker programs, Product Theaters, Symposiums, Consulting agreements, and 1:1 engagement. Strategic Partner Deliver successful project leadership that brings value back to the Brands, AstraZeneca, KEEs and the Regional Customer Director team. Ensure the team develops KEE Engagement plans for targeted customers. Manage senior stakeholders by collaborating and working in close partnership with internal partners across Sales, Brand Teams, Marketing, Medical Affairs, Market Access, and Global, ensuring the franchise has a market leadership presence with HCPs and in the key accounts where we hold KEE relationships. Lead the consolidation and strategic recommendations for insights back to shape brand strategy across the current and future Immunology portfolio. Reconcile strategic priorities and activity plans across Immunology brands to effectively build AZ Immunology across the industry. Provide team leadership for the RCD team that ensures alignment with strategic priorities Foster an environment that allows for growth and development of the team. Minimum Qualifications Bachelor's Degree in related field required. Previous experience across multiple functions, including Sales, District Sales Manager, Commercial Business Director, Brand/Marketing, Market Access, Commercial Operations, and/or Medical Affairs. Line management experience. Clinical experience in Rheumatology, Dermatology and other Immunology Diseases (strongly preferred). Previous experience building, implementing, and executing project plans, programs, and related activities. 10+ years' work experience in pharmaceutical or biotech. Strong verbal and written communication skills. A team-first leader who will flourish in a collaborative environment and work to foster and encourage a culture of collaboration across their team. This is a remote role. Candidate should live close to a major airport. Travel is required in this role (approximately 40–50%) including regular visits to our HQ US office Preferred Qualifications Advanced degree in related field Established relationships with Key External Experts in Rheumatology and Immunology space strongly preferred. The annual base pay for this position ranges from $ 231,988.80 - 347,983.20 USD. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered include a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. Date Posted 15-Oct-2026 Closing Date 28-Oct-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

Define and execute US patient support strategy for a cell and gene therapy portfolio, including launch readiness, patient journeys, and scalable support models. | Requires a bachelor's degree and 10+ years in pharmaceutical, biotech, or healthcare roles, with specific market access or patient services experience and deep cell and gene therapy and launch-planning knowledge. | Director, Patient Services Strategy, US Cell & Gene Therapy Office Location: Gaithersburg, MD (3 days minimum per week) Remote is not available for this role. The Director, Patient Services Strategy, US Cell & Gene Therapy, will build the patient services strategy for AstraZeneca’s portfolio from concept through execution. Reporting to the Senior Director, US Patient Support Strategy and Brand Engagement within Access Strategy, this individual contributor will partner across Brand Marketing, Market Access, Commercial Operations, Medical, Digital, and launch teams to create differentiated support solutions and influence enterprise strategy. This high-visibility role offers global exposure and the opportunity to design support models for Cell & Gene Therapy patients, caregivers, referral networks, and treatment centers. The Director will build commitment, turn competing perspectives into clear choices, and protect the standards, decisions, and timelines required for delivery. The initial mandate is to create the US strategy and advance launch readiness across forthcoming assets. Priorities include defining the future-state model, closing capability gaps, sequencing investments, negotiating trade-offs, and scaling asset-specific solutions across the enterprise. Key Responsibilities Enterprise Accountability Leadership: Own the US Patient Support strategy and operating model, defining priorities, capabilities, investments, decision rights, launch readiness, and outcomes. Portfolio Investment Strategy: Develop multiyear recommendations, negotiate resource priorities, and present business cases and trade-offs to senior leaders. Integrated Support Models: Partner across commercial, access, operations, digital, and IT teams to create support offerings for complex treatment pathways. Organizational Capability: Build Cell & Gene Therapy expertise, scalable frameworks, and effective ways of working across US Patient Support. Launch Readiness & Commercialization Program Leadership & Launch Execution: Direct launch workstreams through implementation, integrating roadmaps, dependencies, decisions, readiness, and success measures. Governance & Cross-Functional Integration: Establish decision paths and accountability, resolve issues, and embed patient support across launch, access, and field-readiness plans. Patient Experience & Journey Design Journey Mapping: Map patient, provider, caregiver, and treatment-center journeys to identify barriers across referral, access, treatment, monitoring, and follow-up. Experience Research: Use customer research to shape services that simplify access and improve engagement. Cross-Functional Leadership Strategic Partnership: Build shared ownership across functions while maintaining clear boundaries around scope, governance, accountability, and delivery. Executive Advisory: Translate data, customer insights, and business implications into recommendations that shape US and global strategy and investment. Matrix Leadership: Earn commitment without hierarchy, resolve tension, negotiate outcomes, and keep teams and partners aligned to milestones. Insights & Analytics Market Intelligence: Track Cell & Gene Therapy support models, customer expectations, and industry benchmarks. Performance Measurement: Define success measures and use qualitative and quantitative insights to optimize services. Qualifications Minimum Requirements Bachelor's degree required; advanced degree preferred. 10+ years in pharmaceutical, biotech, healthcare, market access, patient services, customer experience, marketing, or commercial roles. Experience leading cross-functional strategy from concept through implementation, coordinating workstreams, decisions, risks, and milestones. Deep understanding of Cell and/or Gene Therapy patient support, reimbursement, access, and healthcare navigation. Experience supporting launch planning or commercialization initiatives. Experience developing patient journeys and customer experience strategies. Ability to earn trust, build followership, influence without authority, challenge constructively, and hold boundaries. Ability to convert complexity into an executable strategy and negotiate decisions balancing patient, business, and partner needs. Commit to average 3 days per week in office in Gaithersburg. Preferred Requirements Oncology, Rare Disease, Specialty Pharmacy, or Market Access experience. Experience working with treatment centers, referral networks, and complex site-of-care models. Knowledge of digital health, CRM platforms, patient engagement technologies, and support program operations. Experience managing agencies, consultants, technology vendors, or patient support partners. The annual base salary (or hourly rate of compensation) for this position ranges from $210,856 - $242,785. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. Date Posted 08-Oct-2026 Closing Date Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

Lead import/export and Free Trade Zone operations across a cell therapy network, building scalable processes, managing brokers, and ensuring compliant cross-border movement. | Requires a relevant bachelor's degree, substantial customs brokerage, trade compliance, or global logistics experience, and strong FTZ and regulated biopharma knowledge. | Introduction to the Role   At AstraZeneca Cell Therapy, we are building the capabilities required to deliver complex, personalized therapies through a highly coordinated, patient-centered, and globally scalable supply chain. As our network, geographic footprint, and operational complexity continue to expand, trade compliance operations are critical to ensure that patient materials, critical manufacturing inputs, intermediates, and finished product move compliantly, predictably, and without avoidable delay across borders.   The Director, Cell Therapy Trade Compliance Operations will set the strategic direction and lead the global operating model for import/export and Free Trade Zone (FTZ) execution across the Cell Therapy network. This role will establish the capabilities, governance, processes, systems, and organization required to support reliable day-to-day execution, network expansion, and future commercial readiness.   The Director will own operational performance and business continuity for cross-border trade execution, including shipment holds, customs delays, documentation issues, broker performance, FTZ operations, and other events that may affect patient timelines, manufacturing continuity, or inventory control. The role will drive standardization, digitization, visibility, and continuous improvement across the network while ensuring alignment with customs requirements, FDA/CBER import expectations, and applicable internal procedures.   This role provides strategic and people leadership for the team responsible for operational trade compliance execution. The Director will partner closely with Patient Supply Operations, Global Supply Chain, Manufacturing, Quality, Regulatory, Finance, Procurement, Digital, and external service providers to ensure that trade compliance strengthens the delivery system supporting patient and product journeys.   This is a hybrid position with a requirement to work in the office, on average, three days per week.     Key Accountabilities   * Set the global trade compliance operations strategy and operating model for import/export and FTZ execution across the Cell Therapy network. Establish governance routines, execution rhythms, escalation pathways, role clarity, decision rights, and cross-site ways of working that support reliable and compliant operations. * Own end-to-end operational performance for the import and export movement of patient materials, manufacturing inputs, intermediates, and finished product. Ensure compliant and timely execution of customs entry, shipment coordination, broker engagement, FTZ activity, documentation management, and issue resolution. * Lead first-line escalation and business continuity management for cross-border trade execution issues, including shipment holds, customs delays, documentation deficiencies, broker performance concerns, FTZ operational issues, and other disruptions that may affect patient timelines, manufacturing continuity, or inventory control. * Establish and maintain the trade compliance governance framework, including performance standards, escalation criteria, risk controls, operating reviews, compliance metrics, issue management, and decision-making forums across internal teams and external service providers. * Drive process excellence and scalability through workflow simplification, bottleneck removal, standard work, automation, and repeatable operating methods that support network expansion, increasing shipment volumes, new modalities, and growing operational complexity. * Define the digital and data strategy for trade compliance operations by partnering with business and Digital stakeholders to improve workflows, dashboards, KPI reporting, exception tracking, system integration, master data quality, and operational transparency. * Own operational documentation and standard work for shipment execution, FTZ processes, broker coordination, escalation management, issue resolution, business continuity, and execution controls. Ensure that SOPs, work instructions, playbooks, training materials, and governance documentation remain current and aligned with regulatory and business requirements. * Lead broker and service-provider strategy and performance management for customs brokers, freight forwarders, FTZ operators, and related partners. Establish performance expectations, monitor service delivery, lead issue resolution and escalations, and provide operational input to scorecards, sourcing decisions, and structured business reviews. * Lead trade compliance readiness for network expansion involving new countries, sites, lanes, products, modalities, and operating models. Ensure that import and export requirements, broker readiness, documentation processes, customs classifications, permits, regulatory considerations, and FTZ implications are understood, resourced, and deployable before operational launch. * Use data and risk-based insights to improve performance by monitoring trends across customs clearance, shipment holds, broker performance, FTZ execution, documentation quality, exception resolution, and compliance risk. Translate insights into corrective and preventive actions that improve predictability, compliance, resilience, and service reliability. * Provide strategic partnership to senior stakeholders across Patient Supply Operations, Global Supply Chain, Manufacturing, Quality, Regulatory, Finance, Procurement, Digital, and Commercial Operations. Advise on trade compliance risks, investment requirements, operating-model decisions, and mitigation strategies. * Build and lead a high-performing global team, establishing the organization, capabilities, role clarity, workload priorities, network coverage, and talent-development plans required to support current and future Cell Therapy operations. Provide coaching, development, performance management, and succession planning. * Champion organizational learning and continuous improvement by embedding lessons learned, standardizing successful practices, strengthening controls, and ensuring that the trade compliance operating model evolves as programs progress from clinical development toward registration and commercialization. * Support the clinical-to-commercial transition by establishing trade compliance capabilities, governance, service-provider models, and operational controls that can scale with commercial distribution, changing channels, country expansion, and future product and patient requirements.   Essential Skills and Experience   * Bachelor’s degree in Supply Chain, International Business, Life Sciences, Logistics, Engineering, or a related field. * 12+ years of progressive experience in customs brokerage, import/export operations, trade compliance, global logistics, or supply chain operations within a regulated environment. * Demonstrated experience owning or leading global trade compliance operating models across multiple sites, countries, products, lanes, or business units. * Strong experience with Free Trade Zone or bonded operations, customs entry processes, broker governance, import/export execution, documentation controls, and cross-border issue resolution. * Proven ability to establish and scale governance frameworks, performance-management processes, risk controls, standard work, and business-continuity capabilities. * Demonstrated success leading process transformation, operational digitization, data visibility, workflow improvement, and scalable business-process design. * Experience managing customs brokers, freight forwarders, FTZ operators, and other external service providers, including performance reviews, service-level expectations, escalation management, and corrective actions. * Strong knowledge of customs and import/export requirements relevant to biopharmaceutical operations, including FDA/CBER import expectations and applicable country-specific requirements. * Working knowledge of GDP, GxP, and regulated logistics practices relevant to cross-border execution in biopharmaceutical environments. * Demonstrated people-leadership experience, including building, developing, and leading high-performing teams in a matrixed and globally distributed organization. * Executive-level communication, stakeholder-management, influencing, and decision-making skills, with the ability to translate complex trade compliance matters into clear business risks, recommendations, and actions. * Ability to balance strategic leadership with operational rigor and intervene directly when necessary to protect patient supply, manufacturing continuity, compliance, or inventory control. * Flexibility to support global time zones and time-critical operational escalations as needed.   Desirable Skills and Experience * Advanced degree, such as an MS, MBA, or equivalent. * Experience supporting clinical-to-commercial transition, global expansion, country enablement, or network scale-up in a complex biopharmaceutical supply environment. * Experience with cell therapy, gene therapy, ATMPs, biologics, vaccines, or other specialized pharmaceutical products. * Experience supporting time-critical, cryogenic, temperature-controlled, or highly specialized logistics operations. * Experience using Excel, Power BI, Tableau, Smartsheet, SAP, or similar tools for reporting, workflow management, data analysis, and operational visibility. * Experience establishing or improving trade compliance technology, broker-management systems, shipment visibility tools, or exception-management platforms. * Experience presenting trade compliance strategies, operational risks, investment proposals, and performance outcomes to senior leadership or governance bodies. The annual base pay (or hourly rate of compensation) for this position ranges from 144,997.6 to 212,996.4 USD. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.  When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. Why AstraZeneca: Here, you are trusted to take accountability and make change real—pairing scientific ambition with digital innovation to speed therapies to patients. You will work with expert partners across disciplines, using data, automation, and practical problem-solving to reimagine how critical materials flow through a complex, regulated network. We move decisively and learn fast, valuing kindness alongside ambition, so you can contribute boldly, grow your craft, and see the impact of your decisions reflected in patient outcomes and enterprise progress. Call to Action: If you are ready to design, lead, and scale a disciplined, data-driven trade compliance operation that keeps cell therapies moving to patients, take the next step and share your story with us today. #LI-Hybrid Date Posted 07-Oct-2026 Closing Date 29-Nov-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

Lead regional customer directors to build key external expert advocacy, generate brand insights, plan national congress strategies, and coordinate commercial partnerships across sales, marketing, and medical affairs. | Requires a bachelor's degree, at least 10 years in pharmaceutical or biotech, line-management experience, and clinical expertise in cardiovascular, renal, and metabolic disease areas. | Cardiovascular, Renal & Metabolism (CVRM) At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person. The Senior Director, Regional Customer Team, leads the Regional Customer Director team responsible for identifying & developing KEE advocacy, generating disease and brand specific insights, co-leading national/regional/local congresses, identifying and coaching brand speakers and leading advisory boards across the Cardiovascular, Renal & Metabolism (CVRM) portfolio. This role builds the strategy and leads the Regional Customer Directors in working with multiple stakeholders and partners at headquarters, including the Brand team, Sales, Market Access, and Medical Affairs. Collaborating nationally as well as at the area and regional level, the Senior Director identifies and develops current and future Key External Experts (KEE) in CVRM for activities based on commercial value, driving greater engagement and advocacy while informing insights and brand strategy for the CVRM franchise. What you'll do Provide strategic direction to the team of Regional Customer Directors and Marketing Managers/Associate Directors responsible for HCP Scientific Communications. Build the KEE engagement and lead the development of the cross functional KEE Advocacy Plan for US KEEs. Ensure a robust depth of connection with CVRM Commercial Key External Expert relationships at the national, regional, and area level. Proactively identify opportunities in the identification and development of future KEEs and influencers (up-and-comers). Co-develop the National Congress strategy for CVRM with the marketing team and oversee all KEE engagement at Congresses. Ensure Regional plans are developed, compliant, and aligned with the Medical, Marketing, and Sales strategies for the brands, including product theaters, speaker programs, booths, and ESE interactions. Utilize input from KEEs to help build market leadership, advocacy, and commercial strategies through appropriate tactics such as Ad Boards, Virtual Community, Expert Panels, Speaker programs, Product Theaters, Symposiums, Consulting agreements, and 1:1 engagement. Strategic Partner Deliver successful project leadership that brings value back to the Brands, AstraZeneca, KEEs and the Regional Customer Director team. Ensure the team develops KEE Engagement plans for targeted customers. Manage senior stakeholders by collaborating and working in close partnership with internal partners across Sales, Brand Teams, Marketing, Medical Affairs, Market Access, and Global, ensuring the franchise has a market leadership presence with HCPs and in the key accounts where we hold KEE relationships. Share pertinent insights back to the Executive Director, the Marketing Team, the Customer Director team, and other key stakeholders and partners. Reconcile strategic priorities and activity plans across CVRM brands to effectively show up as one US CVRM team to US KEEs Provide team leadership for the RCD team that ensures alignment with strategic priorities. Foster an environment that allows for growth and development of the team. Minimum Qualifications Bachelor's Degree in related field required. Previous experience across multiple functions, including Sales, District Sales Manager, Commercial Business Director, Brand/Marketing, Market Access, Commercial Operations, and/or Medical Affairs. Line management experience. Clinical experience in Cardiovascular, Renal, and/or Metabolic disease (CVRM). Previous experience building, implementing, and executing project plans, programs, and related activities. 10+ years' work experience in pharmaceutical or biotech. Strong verbal and written communication skills. A team-first leader who will flourish in a collaborative environment and work to foster and encourage a culture of collaboration across their team. This is a remote role. Candidate should live close to a major airport. Travel is required in this role (approximately 40–50%). Preferred Qualifications Advanced degree in related field Established relationships with Key External Experts in the CVRM space (Cardiology, Nephrology, and/or Endocrinology) are strongly preferred. The annual base pay for this position ranges from $ 231,988.80 - 347,983.20 USD. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered include a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. Why AstraZeneca? When we put diverse cross-functional teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. Join us in our unique and ambitious world. AstraZeneca offers an environment where you can be at the forefront of healthcare innovation. With opportunities to shape medical practices and contribute to groundbreaking changes in asthma treatment strategies, you'll find yourself immersed in a fast-paced, collaborative atmosphere. Our commitment to improving patients' lives drives us to leverage science and technology efficiently. Here, you'll be part of a thriving team that encourages development without borders. Ready to make a meaningful impact? Apply now and join us on this exciting journey! Date Posted 06-Oct-2026 Closing Date 19-Oct-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

Lead development and execution of enterprise-wide detection strategies across cloud, on-premises, and OT environments, overseeing detection content, purple team exercises, and AI/automation integration. | Over 5 years managing detection engineering or security operations at enterprise scale with a bachelor's degree in information security or related field. | Leverage technology to impact patients and ultimately save lives Do you have expertise in, and passion for, information technology? Would you like to apply your expertise to impact the IT strategy in a company that follows the science and turns ideas into life changing medicines? If so, AstraZeneca might be the one for you! ABOUT ASTRAZENECA AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world’s most serious disease. But we’re more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we're dedicated to being a Great Place to Work. ABOUT ROLE: The Director, Cyber Security Detection Engineering is a senior leader in the Cyber Operations function, based in Gaithersburg, Maryland, working with the Head of Cyber Operations. The role encompasses command of enterprise detection capabilities across cloud, on-premises, and OT/ICS environments, ownership of detection governance and validation, and delivery of executive reporting, coverage assessments, and capability maturation in partnership with GSOC, CTI, Vulnerability Management, Offensive Security, IT, Legal, Risk and Compliance, and business customers. What You'll Do: Detection strategy and roadmap: Direct the development and execution of comprehensive detection engineering programmes aligned to interpersonal risk appetite and threat landscape; establish capability roadmaps spanning data engineering, detection development, purple teaming, and automation/AI. Data engineering oversight: Ensure robust data pipelines support detection activities through telemetry collection, normalization, and quality assurance across hybrid and OT environments; define data retention, schema standards, and platform configuration to enable effective threat detection. Detection content development: Oversee creation, testing, and deployment of detection logic across SIEM, EDR, and cloud-native tooling; enforce detection standards, naming conventions, and MITRE ATT&CK mapping; prioritise coverage based on threat intelligence and risk assessments. Purple Team Exercising: Oversee purple team operations to validate detection efficacy systematically; orchestrate adversary emulation exercises across technology domains; drive remediation of detection gaps identified through testing and operational feedback. Automation and AI integration: Operationalise AI agents, machine learning models, and orchestration workflows to enhance detection accuracy, reduce false positives, and augment GSOC analyst capabilities; oversee development of automated enrichment, triage, and investigation playbooks. Metrics and reporting: Own detection engineering targets (e.g., MITRE ATT&CK coverage, mean time to detect, false positive rates, purple team success metrics) and deliver executive-ready briefings, dashboards, and quarterly maturity assessments. Policy and governance: Develop and enforce detection engineering policies, standards, and quality frameworks; maintain detection content libraries with version control and organizational change field; ensure regulatory compliance in data handling. People Leadership: Strategy and planning: Develop and maintain detection engineering area plans aligned to Cyber Operations strategy; set direction and goals with autonomy across data engineering, detection development, purple teaming, and automation functions. Performance and tiers: Define and review reporting and team targets; align objectives to detection outcomes, coverage improvements, and operational efficiency. Talent and capability: Lead inclusive recruitment; build career paths and targeted upskilling in detection development, threat hunting, cloud security, OT/ICS detection, and SOAR/AI through multi-functional, regional, and external partnerships. Knowledge, Experience, and Understanding Of: Detection engineering lifecycle: Proven leadership across detection development, testing, deployment, and tuning at enterprise scale; deep understanding of detection logic design, coverage mapping, and efficacy validation. Threat detection frameworks: Extensive knowledge of MITRE ATT&CK, Cyber Kill Chain, and detection engineering methodologies; experience mapping organisational coverage and prioritising development based on threat intelligence. Purple team operations: Experienced in designing and accomplishing adversary emulation exercises; skilled in translating purple team findings into actionable detection improvements and coverage enhancements. Automation and AI: Experience operationalizing modern detection platforms (SIEM, XDR, SOAR) including integration of artificial intelligence, machine learning models, and agentic features to enable detection at scale. Data engineering and platforms: Proficient with data pipeline architecture, log aggregation, normalisation, and query optimisation; solid grasp of data quality requirements for effective detection. Cloud, identity, and endpoint detection: Deep understanding of detection approaches across multi-cloud environments, identity systems, endpoints, and network infrastructure; familiar with cloud-native security services and integration patterns. Manufacturing Operational Technology/Industrial Control Systems: Coordinating detection engineering in industrial/OT environments with safety, availability, and production continuity considerations; knowledge of industrial protocols and OT-specific threats. Minimum Skills & Experience Required Education: Bachelor's degree in information security, computer science, or related field (or equivalent experience). Enterprise-scale detection leadership: Over 5 years managing detection engineering or security operations in enterprise-sized organisations, commanding capabilities across hybrid cloud, on-premises, and OT environments. Global coordination with distributed teams: Experience integrating and working alongside global, 24×7, geographically dispersed teams to deliver detection capabilities and support security operations missions. Communication and facilitation: Well-developed skills to explain complex technical concepts in clear business terms; produce concise written material (executive updates, coverage reports); and lead briefings to diverse stakeholders. Analytical decision making: Ability to analyse complex threat landscapes, assess detection gaps, and balance strategic capability development with tactical operational requirements, risk appetite, and resource constraints. Customer orientation and cross-cultural working: Demonstrated ability to collaborate across regions and functions (GSOC, IT, Legal, GRC, business units) with a strong service approach and commitment to enabling organisational resilience. Preferred Skills & Experience: Certifications: Security certifications preferred (e.g., CISSP, CISM, GIAC such as GCIA/GCDA/GMON; cloud certifications; ITIL). When we put unexpected teams in the same room, we unleash bold thinking with the power to encourage life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. The annual base pay for this position ranges from $169,320.00 - $253,980.00 USD Annual. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. Are you ready to bring new insights and fresh thinking to the table? Fantastic! We have one seat available, and we hope it’s yours. Apply today. AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. WHY JOIN US ? We’re a network of high-reaching self-starters who contribute to something far bigger. We enable AstraZeneca to perform at its peak by delivering premier technology and data solutions. We’re not afraid to take ownership and run with it. Empowered with unrivalled freedom. Put simply, it’s because we make a significant impact. Everything we do matters. Date Posted 12-Aug-2026 Closing Date 25-Aug-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

Lead a CTI team to deliver intelligence reducing enterprise risk across multiple environments. | Over 10 years in cyber threat intelligence or related fields with 5+ years technical leadership and deep MITRE ATT&CK expertise. | About AstraZeneca AstraZeneca is a global, science-led, patient-focused biopharmaceutical company dedicated to discovering, developing, and commercialising prescription medicines for serious disease. We’re committed to being a Great Place to Work. About the Role The Director of Cyber Threat Intelligence will lead a highly technical CTI function within AstraZeneca’s Cybersecurity Operations division, managing a team of analysts to deliver strategic, operational, and tactical intelligence that measurably reduces risk across the enterprise, including manufacturing, clinical trial platforms, and R&D environments. This role anchors CTI to “intel-to-action” outcomes, partnering closely with Vulnerability Management, Detection Engineering, and Incident Response to harden controls, prioritize patching, improve detections, and accelerate response. Key Responsibilities Program Leadership and Strategy: Define CTI vision, operating model, and roadmap aligned to AstraZeneca’s cyber risk reduction strategy, with special emphasis on manufacturing continuity, clinical data integrity, and R&D IP protection. Adversary Prioritization Framework: Design and operate a scoring rubric that ranks actors based on intent/capability/relevance, TTP emergence and prevalence, organization-specific exposure to known vulnerabilities/CVEs, and global “viral” events, maintaining dynamic watchlists and escalation triggers. MTTI Metric and Analytics: Implement analytic methods to estimate mean time-to-impact per adversary (from initial access to material business impact) using internal telemetry, historical incidents, industry reporting, and confidence levels, performing comparisons with IR’s MTTC to drive control improvements. Attack Path Modeling: Build and maintain end-to-end attack path models from initial access to material impact across IT-to-OT pivots, clinical platforms, and R&D environments, mapping steps to MITRE ATT&CK (Enterprise/ICS), identify control gaps and choke points, derive detections-as-code and hunt hypotheses, and support validation efforts including purple-team exercises and adversary emulation to ensure enterprise hardening and measurable risk reduction. Dark Web and Closed-Source Monitoring: Establish collection and monitoring across dark web forums, marketplaces, breach dumps, and closed channels to identify emerging TTPs, credential leaks, data exposure, access-broker listings, and targeting of manufacturing, clinical, or R&D assets, integrating validated findings into TIP/SIEM pipelines, trigger takedown requests where feasible, and deliver rapid advisories with confidence ratings and specific actions for Vulnerability Management, Detection Engineering, and IR. Third-Party and Ecosystem Intelligence: Deliver risk insights for CROs/CMOs/logistics/technology vendors, monitor credential leakage and domain spoofing, and support/coordinate takedown operations when needed. Structured Threat Actor Attribution (Diamond Model): Lead disciplined attribution using the Diamond Model (adversary, capability, infrastructure, victim) and complementary frameworks, correlating TTPs, tooling lineage, code-reuse, infrastructure overlaps, and victimology with confidence levels and analytic caveats, documenting hypotheses, alternative explanations, and disconfirming evidence, and producing reusable actor profiles and pivot paths that inform prioritization, detections, hunts, and incident response playbooks. Support Vulnerability Management: Partner with Vulnerability Management to contextualize CVEs (exploitability, weaponization, external scanning telemetry, compensating controls) and deliver risk-based patching prioritization across AstraZeneca’s estate including IT/OT, clinical platforms, and lab environments. Support Detection Engineering: Develop detection use cases to feed our detection-as-code pipeline and support detection ATT&CK coverage mapping, content tuning, and false-positive reduction, ensuring feedback loops from hunts and incidents continuously improve detection quality. Support GSOC/Incident Response: Provide real-time adversary context that is highly technical including kill-chain reconstruction, containment recommendations, and countermeasures, producing post-incident intelligence retrospectives and detection/architecture improvements. Operational and Executive Reporting: Produce daily threat intelligence highlights, threat actor/campaign profiles, quarterly threat briefings, and other ad hoc intelligence products, ensuring products include quantified risk narratives for senior leadership that also align findings to regulatory expectations and business impact. Tooling and Automation: Optimize integrations across TIP, SIEM, EDR, case management, and telemetry; manage indicator lifecycle, automate enrichment, and measure source fidelity/bias. External Engagement: Lead participation with sector bodies (e.g., H-ISAC), peer sharing groups, and government/industry partners; track and assess global events and rapidly translate into actionable enterprise guidance. Team Leadership and Development: Recruit, mentor, and grow a diverse team of CTI analysts; build career paths, training plans, and knowledge-sharing practices; foster a culture of technical excellence and clear, actionable communication. Minimum Qualifications Leadership and Strategic Impact: 10+ years in cyber threat intelligence, detection engineering, incident response, or related domains; 5+ years leading technical CTI teams in global enterprises. Demonstrated ability to set vision, influence strategy, and deliver outcomes tied to enterprise risk reduction. Decision Making and Accountability: Proven ownership of adversary-centric CTI programs that directly drive vulnerability prioritization, detections-as-code, hunts, and incident response. Comfortable making data-driven decisions with clear trade-offs and confidence levels. Technical Depth (ATT&CK Enterprise/ICS): Deep expertise mapping TTPs to MITRE ATT&CK, defining coverage strategies, and translating gaps into high-fidelity detections and hunt hypotheses; skilled in industrial/OT contexts. Attack Path Modeling and Risk Translation: Hands-on delivery of end-to-end attack paths across IT-to-OT pivots, clinical platforms, and R&D environments; validation via purple-team/adversary emulation; ability to convert findings into prioritized control roadmaps and measurable risk reduction. Adversary Prioritization and Scoring: Designed and operated tailored actor scoring incorporating intent/capability, TTP emergence/prevalence, org exposure to CVEs, and global/viral events; maintained dynamic watchlists and escalation triggers. Structured Attribution Tradecraft: Applied the Diamond Model and complementary frameworks with documented hypotheses, caveats, disconfirming evidence, and confidence statements; produced reusable actor profiles and pivot paths. Metrication (MTTI vs. MTTC): Built mean time-to-impact metrics per actor and operationalized comparisons to IR's mean time-to-containment to guide control improvements and track program effectiveness. Vulnerability Intelligence for Hardening: Delivered contextual CVE analysis (exploitability, weaponization, external scanning telemetry, compensating controls) and risk-based patch recommendations across IT, OT/ICS, clinical, and lab environments. Detection Engineering Collaboration: Co-developed detections-as-code (e.g., Sigma, KQL, SPL), tuned content to reduce false positives, and closed ATT&CK coverage gaps with feedback loops from hunts/incidents. Incident Intelligence Support: Provided real-time adversary context, kill-chain reconstruction, containment recommendations, and post-incident retrospectives that inform detection and architectural improvements. Collection, Tooling, and Automation: Operated dark web/closed-source monitoring; integrated findings into TIP/SIEM/EDR pipelines; managed indicator lifecycle, automated enrichment, and measured source fidelity/bias. Stakeholder Partnership and Communication: Clear, concise communication of complex technical intelligence to executives and cross-functional partners (Vulnerability Management, Detection Engineering, SOC/IR, OT Security, Clinical Ops, Research IT); ability to influence without authority. Education: Bachelor's degree in a relevant field (Computer Science, Information Security, Intelligence Studies, or equivalent experience). Preferred Qualifications Sector Experience and Regulatory Context: Experience in pharmaceuticals, life sciences, healthcare, or manufacturing; familiarity with GMP/CSV, clinical data obligations, and R&D IP protection. OT/ICS and Critical Operations: Hands-on work with MES, SCADA, PLC ecosystems; ATT&CK for ICS usage; understanding of OT-safe response practices and production continuity implications. Clinical/R&D Platforms: Exposure to CTMS, EDC, IRT, ELN, LIMS, HPC, and data lake environments; experience safeguarding data integrity and sensitive research/IP. Program Metrics and Outcomes: Built dashboards tracking MTTI by actor, ATT&CK coverage indices, intel-informed patch SLAs, hunter ROI, and executive risk narratives; experience presenting to senior leadership and risk committees. Advanced Tooling/Automation: TIP administration, SIEM/EDR content engineering, enrichment/orchestration pipelines, case management integration, and indicator lifecycle automation at enterprise scale. Threat Modeling and Quantification: Ability to translate attack paths into quantified risk scenarios and prioritized control investments aligned to business objectives and crown jewels. External Partnerships: Active engagement with H-ISAC/ISAOs and government/industry partners; track record of rapidly converting global/viral cyber events into enterprise defenses and executive guidance. Certifications: One or more of GCTI, GREM, GRID, GCIH, CISSP, or equivalent demonstrated expertise. People Leadership: Built diverse, high-performing teams; established career paths, coaching frameworks, and a culture of analytic rigor, technical excellence, and continuous improvement. All roles in IT are expected to demonstrate a mindset of embracing, adopting and appropriately using AI and digital tools in day‑to‑day work to improve outcomes and ways of working. Location Gaithersburg, Maryland. Office Working Requirements When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn’t mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. The annual base pay for this position ranges from $162.536,00 - $243.804,00 USD Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. Date Posted 04-ago-2026 Closing Date 14-ago-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.