AstraZeneca

Compensation

Full Description

The Oncology Data Science – Data, Analytics, and AI Platforms (ODSP) team comprises multiple groups across the Cambridge UK, Boston MA, Gaithersburg MD, and Munich DE sites. ODSP develops technology, software, and data infrastructure to advance our Oncology data science. Our vision is to evolve data science into a driver of innovation within Oncology. We do this by creating a strategic culture that values our data as a true business asset, organizing our data so that it’s accessible and easy to find, integrated, and re-usable for Humans & AI, and building the best computational tools to support scientific decision making. The Oncology Data Science Platforms Team is delivering the FAIR data foundation of clinical, molecular and biosamples data to the Oncology data consumers (scientists, bioinformaticians, data scientists etc.). We are seeking an experienced data operations leader to own end-to-end stewardship of molecular and imaging data arising from clinical trials and related translational studies. This role will define and operationalize FAIR-by-design practices, establish rigorous data specifications, and lead data transfer agreements/processes with CROs, central labs, biomarker vendors, and imaging partners. The Associate Director will build a scalable operating model for ingestion, curation, harmonization, and provisioning across multi-omics and clinical imaging, ensuring quality, compliance, and scientific usability at speed. You will report to the Director, Data Products, Ops & Governance and may be based in Waltham, MA or Gaithersburg, MD. Key Accountabilities Strategy and FAIR Operating Model: Define the FAIR data roadmap, OKRs, and pragmatic standards for ingesting, curating, harmonizing, and provisioning molecular and imaging clinical data; drive enterprise metadata, ontology, and catalog adoption to enable findability and reuse. Data Stewardship for Clinical Molecular & Imaging: Serve as accountable data steward for genomic, proteomic, and other -omics readouts from clinical trials and for digital pathology/imaging modalities (e.g., WSI, radiology DICOM); ensure modality-specific QC, metadata capture, and traceability from site/vendor to analysis environment. Vendor and Lab Integration: Lead the design and implementation of data specifications, data transfer agreements (DTAs), and SLAs with CROs, central labs, biomarker assay providers, and imaging vendors; standardize templates and acceptance criteria; oversee onboarding and performance monitoring. Standards, Compliance, and Governance: Implement data/metadata standards and controlled vocabularies across modalities; embed privacy-by-design and regulatory compliance (e.g., GDPR) and align with clinical data standards and internal governance cadences. Cross-Functional Delivery in Matrix Teams: Drive delivery across cross-functional matrix teams of data SMEs, data engineers, alliance/partnership managers, clinical operations, translational biomarker leads, imaging scientists, biostatistics, quality/compliance, privacy/legal, procurement/vendor management, and IT/security. Orchestrate work plans, dependencies, and acceptance criteria; champion agile/DataOps practices to ensure timely, compliant, and reusable outputs without direct line management responsibilities. Stakeholder Management and Change: Translate scientific and operational needs into clear requirements and delivery plans; communicate risk, value, and trade-offs; drive adoption of standards and tools through training and change management. Minimum Qualifications Education: Master's degree in Data Science, Bioinformatics, Computational Biology, Life Sciences or related; PhD preferred. Experience: 5+ years' experience in data management/operations within Life Sciences/Pharma R&D. Modality Expertise: Demonstrated stewardship of clinical molecular data (e.g., NGS, qPCR, proteomics) and imaging/digital pathology or radiology data within clinical trials, including QC pipelines, metadata capture, and compliance controls. FAIR at Scale: Proven track record implementing and scaling FAIR practices across complex R&D data (digital pathology, genomics/-omics, clinical) with measurable impact on data findability, interoperability, and reuse. Vendor/Lab Data Transfer: Hands-on experience defining data specs, mapping guides, transfer protocols, and DTAs; managing external partners and ensuring timely, quality-compliant data deliveries. Technical: Proficiency with Unix and Python, workflow orchestration (e.g., Airflow, Prefect), data modeling and standards/ontology implementation, data privacy/compliance, and strong stakeholder communication and documentation skills. Preferred Skills Ways of Working/Tools: Agile (Scrum/Kanban), Jira/Confluence; data observability/quality tooling; cloud data platforms (e.g., AWS/Azure/GCP), data catalogs, lineage solutions. Ontologies/References: Familiarity with Gene Ontology, NCI Thesaurus, EFO, HPO, MeSH, BAO; resources such as NCBO BioPortal, EBI OLS; references including UniProt, Ensembl, ChEMBL, EntrezGene, ClinicalTrials.gov. Clinical Standards: Working knowledge of CDISC SDTM/ADaM and interoperability frameworks (FHIR/OMOP) for RWE integration; experience aligning biomarker/imaging datasets to clinical contexts and study metadata. Imaging and Pathology: Understanding of DICOM, WSI formats, PACS/LIMS integrations, digital pathology QC, and image-derived features; experience with image metadata standards and de-identification. Analytics/Visualization: Experience enabling operational and QC dashboards (e.g., Power BI/PowerQuery) and provisioning curated datasets to scientific users and statisticians. Why AstraZeneca? At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare. So, what’s next? Are you ready to bring new ideas and fresh thinking to the table? Great! We have one seat available, and we hope it’s yours. The annual base pay for this position ranges from $128,000 to $192,000. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. Date Posted 12-Feb-2026 Closing Date 22-Feb-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.