Revolution Medicines

Leading and managing the medical writing department to deliver high-quality, compliant regulatory documents in a biotech/pharma setting. | Extensive experience in regulatory medical writing, leadership, and a background in life sciences or pharmacy, preferably with oncology experience. | Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: The Senior Director of Medical Writing will be responsible for helping to develop strategic leadership and management of the medical writing function and involves both a people and project-orientated focus. This position reports to the Executive Director, Medical Writing. Driving for success in terms of people, projects, and productivity of medical writing, including all deliverables in alignment with corporate goals. Providing leadership across the medical writing department through strategic input, continual process improvement, and innovation in the development and implementation of a strategic view of regulatory documents. Assuring the successful completion of high quality, timely and compliant document deliverables. Structuring resourcing to ensure an effective and cost-efficient approach to covering portfolio workload and goals while ensuring sustainability and alignment with corporate goals. Providing medical writing leadership and guidance to full-time and contract medical writers. Assisting the Executive Director, Medical Writing, in developing budget and resource requirements for contract medical writers across multiple programs for each fiscal year. Demonstrating current and applied knowledge and understanding of regulatory requirements and standards to ensure consistent application, adherence, and timely achievement of compliant deliverables. Serving as a primary subject matter expert for the planning, design, and preparation of clinical and regulatory documents. Authoring and reviewing clinical regulatory documents as needed, including assisting teams in responding to regulatory requests. Attracting, hiring, and retaining qualified contract medical writing professionals Working within the medical writing function and cross-functionally to test and develop policies regarding the use of structure content management and/or generative AI as part of clinical regulatory document processes. Collaborating and partnering with cross functional leaders and other staff across project management, regulatory affairs, clinical operations, clinical development, biostatistics, and other functions. Representing the medical writing department externally with academic institutions, industry groups/peers, vendors and other entities to develop expertise and drive industry standards and best practice. Required Skills, Experience and Education: Doctoral degree and 8 years of regulatory medical writing experience Master’s degree and 10 years of regulatory medical writing experience Bachelor’s degree and 15+ years of regulatory medical writing experience At least 5 years of experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources. Preferred Skills: Academic preparation in life sciences or pharmacy with at least 15+ years of related experience in the pharmaceutical/biotechnology industry. Experience in oncology. Strong understanding of drug development process. Experience with authoring major clinical regulatory documents, including protocols and amendments, study reports, and marketing application summaries. Experience with structured content management and/or generative AI use in the medical writing space preferred but not required. Hybrid #LI-JC1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range $244,000—$305,000 USD

Lead and execute medical publication and communication strategies for oncology pipeline assets, ensuring compliance and scientific integrity. | Advanced degree in biomedical sciences or related field, 10+ years in Medical Affairs or Medical Communications within biotech/pharma, experience in publication planning, stakeholder engagement, and team leadership. | Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: As a new member of the Revolution Medicines team, the Senior Director, Medical Communications will lead the development and execution of a comprehensive medical communications strategy, ensuring alignment across internal and external stakeholders in preparation for the company's first commercial launch in pancreatic cancer and the progression of additional pipeline assets in NSCLC, colorectal cancer, and other solid tumors. Reporting into Global Medical Excellence within Medical Affairs, this role will oversee scientific communications platforms and publication strategies and contribute to medical content supporting the organization’s medical and scientific engagement efforts. Key responsibilities include: Publications Strategy & Execution Lead the development and execution of the global publication plan, ensuring alignment with clinical and scientific objectives. Oversee and provide strategic direction for medical writing, publication planning meetings, the submission process, and timely/high-quality scientific communications and publications. Ensure compliance with Good Publication Practices (GPP), ICMJE guidelines, and industry standards. Manage and optimize the use of Datavision or other publication management systems to ensure visibility, collaboration, and compliance across teams. Scientific Communications Platform Develop and maintain the scientific narrative and core communication messages for pipeline programs. Oversee creation of scientific platform materials to ensure consistency and scientific integrity in external communications. Ensure alignment with Medical, Clinical, and Commercial teams for accurate and impactful messaging. Congress Strategy & Scientific Exchange Drive scientific congress planning and execution, including coordination of symposia, abstracts/posters, presentations, and medical booth presence. Identify opportunities to amplify Revolution Medicines' scientific presence at major oncology congresses (e.g., ASCO, ESMO, AACR). Internal Education & Change Management Implement change management strategies to enhance internal understanding of best practices in publications strategy and execution. Educate internal stakeholders on scientific publication standards, compliance requirements, and best-in-class medical communication practices. Build trust across the organization in the Medical Communications function, reinforcing its role as the central authority on publication strategy, planning, and execution. Cross-functional Collaboration & Leadership Serve as a key member of the Medical Excellence team, contributing to medical strategy and launch planning. Partner with Field Medical (MSLs), Medical Information, and Medical Education to ensure a cohesive medical communications and engagement strategy. Work with internal and external stakeholders to contribute to educational content for KOLs, HCPs, and internal teams. Required Skills, Experience and Education: Advanced scientific or medical degree (PhD, PharmD, MD) preferred; MS or equivalent experience in biomedical sciences or related field considered. 10+ years of experience in Medical Affairs, Medical Communications and publications planning/execution within the biotechnology or pharmaceutical industry. Experience leading scientific publication strategy, medical education initiatives, and external stakeholder engagement. Deep understanding of industry guidelines, and best practices (ACCME, PhRMA Code, FDA, OIG, AdvaMed, Sunshine Act). Proven ability to develop and execute medical communication strategies aligned with company and scientific priorities. Expertise in scientific communications planning, data dissemination, and medical writing/publication processes, including authorship guidelines (ICMJE, GPP). Familiarity with clinical development and real-world evidence (RWE) and how these influence scientific communication strategies. Ability to navigate cross-functional partnerships with Clinical, Research/Translational Science, Biostatistics and executive teams. Ability to manage external agency relationships, medical writers, and vendors to ensure quality and compliance in content development. Ability to translate complex scientific data into clear, engaging, and compliant communications for different stakeholders. Experience managing and mentoring teams of medical writers, communication specialists, or publication planners. Ability to work in fast-paced, matrixed environments and lead cross-functional initiatives. Proficiency in publication planning software (Datavision, PubStrat, etc.) and scientific engagement tools. Strong project management skills to oversee multiple priorities, timelines, and stakeholders effectively. Excellent communication, interpersonal, and presentation skills to engage internal and external stakeholders effectively. Preferred Skills: Experience in precision oncology and targeted therapies. Previous leadership in launch planning and medical communications/publications strategy. Familiarity with digital tools and innovative solutions for medical communication. #LI-Hybrid #LI-YG1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range $244,000—$305,000 USD

Design and implement capabilities building projects to enable growth and improve ways of working within the Development & Clinical Sciences organization. | Over 10 years of experience in change management, project management, or consulting, with a background in life sciences or biopharma preferred, and strong communication and stakeholder management skills. | Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: The Sr Manager Capabilities Enablement is an internal project manager with a consultant mindset and hands-on approach. This is an execution-focused role that strengthens the business capabilities in the Development & Clinical Sciences (DCS) organization. This role partners closely with the Development Leadership Team and the Program Leads to design and implement capabilities building projects that enable growth and evolving our ways of working. The role is ideal for a Senior Manager–level professional who thrives on execution and has strong project leadership, communication and change management experience. Responsibilities: Enablement Programs & Tools Design and deploy practical solutions (e.g., templates, toolkits, playbooks, workflows) that enable DCS teams in their day-to-day work. Ensure solutions are practical, scalable, and embedded into existing processes. Partners with subject-matter experts to translate complex DCS practices into clear, usable resources. Conduct needs assessment to evolve business processes and drive operational performance. Execution & Delivery Implement frameworks, tools, and processes that enable growth. Own day-to-day planning, coordination, and delivery of capabilities project initiatives, ensuring timelines, quality, and outcomes are met. Data, Insights & Continuous Improvement Track adoption and effectiveness of capabilities enablement initiatives using defined metrics and stakeholder feedback. Identify capability gaps and execution challenges; drive continuous improvement actions. Provide leaders with clear visibility into the capabilities readiness and progress. Stakeholder Partnership & Change Enablement Partner with DCS leaders to support consistent implementation and change adoption. Identify potential resistance points and execute mitigation actions to support engagement. Coordinate closely with functional partners to ensure aligned execution. Required Skills, Experience and Education: 10+ years’ experience in change management, project management or consulting with at least 3 years in pharma/ biotech environment. BS/BA degree in life science, business management, organizational psychology or related discipline. Experience leading complex organizational change efforts. A thorough understanding of the clinical development process within biopharma Excellent verbal and written communication skills with the ability to distill the key points into a succinct summary. Strong interpersonal skills to interact daily with diverse cross-functional internal and external stakeholders. Comfortable providing counsel to senior leaders Self-motivated and able to work independently to execute strategic direction. Preferred Skills: MSc., MA, MBA or Ph.D. a plus Proactive, and collaborative team-player with high energy to keep pace with our growing and evolving company environment. Experience building professional working relationships at all levels within and across the organization. Adaptable, proactive personality style that can prioritize, quickly adapt to changing conditions. Able to function independently in a fluid environment under tight timelines. Advanced skills with MS Office software (Excel, PowerPoint, Word) and Smartsheet.#LI-Hybrid #LI-JC1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range $164,000—$205,000 USD

Manage and lead global clinical-stage drug development programs, ensuring strategic alignment, risk mitigation, and stakeholder communication. | Over 15 years in biotech/pharma with at least 7 years managing global development teams, strong knowledge of drug development processes, and proficiency in project management tools. | Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: This is an exciting, high-profile, and highly visible Program Management opportunity to advance a first-in-Class RAS(ON) Inhibitor through clinical development. The ideal candidate has a strong project management background and is highly self-motivated to drive this investigational asset to patients with a sense of urgency. The Senior Director, Program Management is a strategic-minded partner to the Project Team Leader (PTL); they understand the competitive landscape and clinical context to drive the translation of program strategy into an efficient execution plan They can manage cross-functional dependencies and connections to generate development scenarios leveraging opportunities and addressing program risks. They understand the breadth of cross-functional activities and can foster productive collaborations to ensure successful execution. As a senior member of the Program Management (PM) group, this individual represents the PM function within a team as well as the broader organization. It is incumbent on them to elevate the PM function to fully showcase the value and impact of our area of expertise to deliver on business objectives. They desire to contribute to the overall proficiency and capabilities of the PM group. They serve as a role model for RVMD core values; willing to impart their knowledge and experience to advance the development of more junior group members. Overall, the Senior Director, Program Management can make things happen via productive collaborations in an organizational environment that is rapidly developing its capabilities and infrastructure. This person not only cares about the outcomes but how we get there. The successful candidate will draw upon their experience to: Manage fast-paced clinical-stage global drug development project team as defined by governance strategic imperatives. Provide executional leadership of a complex, multi-indication program. Partner with the PTL in defining program strategy, stakeholder management, and overall program leadership topics. Along with the PTL, accountable to leadership for project execution within the program/portfolio strategy. Establish and maintain functionally integrated project plan and project assumptions (accounting for goals, key objectives, deliverables, risks) to enable accurate project, financial and portfolio analyses for business planning processes. Ensure identification and management of project risks and mitigation plans reporting them to the respective governance bodies. Evaluate alternative development scenarios (comprising costs, timelines, risks, and project strategy) during progression of the program through stage gates and as per business need. Lead the global development team through the preparation and update of key project documents and communications. Lead an efficient information flow within the global cross-functional project team, and internal advisory & governance bodies. Partner with the PTL to provide inspirational leadership and ensure the team achieves and maintains a high-level of sustainable performance. Practice effective meeting and information management including, timely meeting agendas and minutes, facilitate project team meetings, follow up on action items, document meeting materials and decisions, and act as a primary contact for project team related information. Direct the global cross-functional project team leveraging project management and drug development expertise and coach, mentor and engage project team members, ensuring efficient and effective project team operation. Identify, recommend, and implement opportunities for streamlining team and business processes. Participate in establishment and implementation of project management systems and best practices. As an experienced PM, expected to lead, mentor and coach more junior PM members via direct or indirect roles. Support new corporate development activities or other initiatives supporting department, portfolio, or corporate needs. Required Skills, Experience and Education: B.A. or BSc. in Life Sciences and at least 15+ years’ experience in the biotech/pharmaceutical industry with at least 7 years’ direct development project management experience managing cross-functional global development teams. Ability to translate strategy into action utilizing strong influence, negotiation, and conflict management skills as needed. Excellent interpersonal skills, including clear, succinct, and timely communication and proven ability to foster important relationships with key stakeholders. Outstanding verbal and written communication skills with the ability to summarize complex information into simple concepts ability to effectively interact with all levels within the company including internal/external partners and functional areas. Broad knowledge of the clinical drug development process and regulations, coupled with strong proficiency in project management practices, tools, and methodology. Expertise in developing and managing project scope, deliverables, risk & resource requirements including, Schedule / Timeline management, Budget management, and Risk management. Proven track record of good decision making and exercising sound judgment. Experience using Project Management software to manage project timelines and resources (e.g., MS Project, SmartSheet, OfficeTimeline, and OnePager Pro etc.). Strong computer proficiency with MS Office suite, SharePoint and similar internal document archiving systems. Preferred Skills: MSc. or MBA or Ph.D. in Life Sciences a plus. Experience in global (US, Ex-US) drug development teams, and regulatory components is strongly preferable. PMP (Project Management Professional) or other PM certification or equivalent is a plus. Experience in Oncology therapeutic area is strongly preferrable. #LI-Hybrid #LI-JC1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range $244,000—$305,000 USD

Lead clinical pharmacology strategies, design studies, and contribute to regulatory submissions for oncology drug development. | Ph.D. or Pharm.D. with 8-10 years in industry, expertise in pharmacology modeling, and experience with regulatory documents. | Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: We are seeking a highly motivated and energetic individual with a relevant scientific background to be part of the Nonclinical Development and Clinical Pharmacology (NDCP) Organization. As a key member of the Clinical Pharmacology group, you will: Responsible for clinical pipeline delivery through major milestones including IND/CTA, EOP2, and marketing applications NDA/sNDA. Lead the design and execution of an integrated clinical pharmacology and modeling and simulation strategy to guide the clinical development plan. Apply state-of-the-art quantitative pharmacology analyses, including PBPK, translational PK/PD, population PK, exposure-response analyses, and system pharmacology, to guide dose/schedule selection and recommended phase 2 dose and schedule (RP2Ds) selection. Author and provide technical input for regulatory documents and submissions related to all aspects of clinical pharmacology (including protocol, IB, briefing package, etc) and responses to regulatory questions. Engage and work with consultants and/or CROs on clinical pharmacology activities to complement in-house knowledge/expertise and capacities. Represent the clinical pharmacology function in project teams and build strong working relationships with cross-functional teams to impact critical decisions. Abilty to manage internship and fellowship programs. Required Skills, Experience and Education: A Ph.D. or Pharm.D. with 8-10 years of relevant industry experience in Clinical and Quantitative pharmacology. Expertise in clinical pharmacology, hands-on modeling, and simulation skills using NONMEM, R, and/or other modeling and simulation software. Experience with population PK, exposure-response, and advanced mechanistic PK/PD models. Track record of applying modeling and simulation methodologies to inform and accelerate drug development. Well-informed in current and emerging scientific standards of regulatory requirements and expectations. Excellent verbal and written communication skills, and ability to clearly convey complex concepts and findings to both non-specialist and specialist audiences. Strong interpersonal skills, and ability to influence development project and management teams. A critical thinker and passionate team player with high energy who thrives in a dynamic and fast-paced environment. Preferred Skills: Hand-on experience with PBPK models using SimCYP and PK-sim. Prior experience with small molecules in oncology drug development. Prior experience with authoring regulatory documents such as IND/CTA, EOP2, and marketing applications NDA/sNDA. #LI-Hybrid #LI-CT1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range $244,000—$305,000 USD

Leading global communications, fundraising, and organizational strategy for humanitarian and nonprofit organizations. | Extensive leadership experience in nonprofit and humanitarian sectors, with no specific experience in biotech or pharmaceutical marketing, especially in oncology. | This a Full Remote job, the offer is available from: United States Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Reporting directly to the Executive Director of Marketing, the marketing leader will help develop and deliver Revolution Medicine’s marketing plans for one of the company’s lead KRAS programs in preparation for anticipated launches. You will work within the Commercial team to define the marketing strategy and tactically deliver critical marketing activities on the Commercial roadmap, for example, market research and patient journey mapping, branding, messaging and content delivery. You’ll collaborate with cross functional teams to provide a commercial marketing perspective on clinical, medical affairs, and market access initiatives. You will grow your team to support expanding marketing needs. This position is based out of our headquarters in Redwood City, CA. • Partners to shape the strategic marketing plan and oversee launch readiness initiatives based on deep customer insight; develop branding, positioning, messages, story flow and creative imagery to prepare for and deliver successful oncology product launches. • Leads the development and implementation of the therapeutic focused promotional platform (e.g., messaging, market research initiatives, unbranded website etc.). • Prioritizes, develops, and implements promotional and disease education tactics (including print and digital promotions, peer-to-peer programming, and key customer marketing initiatives) that establish value with our customers and contribute to achieving a successful product launch. • Leads partner agency and vendor relationships and workflow. • Operates as ambassador of the company, establishing organization as trusted member of the healthcare community to all relevant stakeholders (Patients, HCPs, Payers, Policy makers, Industry peers). • Develops the Customer Marketing Team to understand the needs of the top institutions, key opinion leaders, the competitor landscape and other important healthcare providers to optimize promotional approach, selling tools, and educational programming. • Demonstrates the ability to quickly understand complex markets, disease states, competitive landscapes, and relevant market and managed care dynamics. • Establishes a strong relationship with medical affairs, and eventually, the sales team and other field-based commercial teams to ensure optimal execution; partner with Sales Training to develop a comprehensive and effective training plan. • Participates in cross-functional teams as marketing lead to gather input for functional activities, and ensure alignment with marketing messaging, e.g., with clinical development, medical affairs, and investor relations. • Ensures strategic and tactical plans meet compliance and regulatory guidelines and company policies. • Delivers marketing operating expenses within budget. • Travels as needed. • Other duties as assigned. Required Skills, Experience and Education: • Bachelor’s degree required (MBA preferred) with at least 12+ years of progressive commercial experience in a biotechnology and/or pharmaceutical company. Successful history of developing and executing the marketing Experience in leading the launch of new products. • Demonstrated ability to derive insights/analytics leading to the development of innovative marketing strategies. • Strong leadership, with the ability to work well cross-functionally and influence across an organization at all levels. • Excellent organizational skills and an ability to prioritize effectively to deliver results within reasonably established timelines. • Ability to represent Revolution Medicines well externally: strong interpersonal skills including verbal and written communication. • Entrepreneurial mindset, with a tolerance for ambiguity, and a passion for helping cancer patients. Preferred Skills: • Proven experience in a smaller, rapidly growing, company. • Targeted oncology product experience strongly preferred. • Sales experience and ideally sales or field leadership. #LI-Remote #LI-JW1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range $244,000—$305,000 USD This offer from "Revolution Medicines" has been enriched by Jobgether.com and got a 82% flex score.

Leading marketing strategy and launch initiatives for oncology products, including market research, branding, and stakeholder engagement. | Over 12 years of progressive experience in biotech/pharma marketing or related fields, with proven product launch success, leadership skills, and industry-specific knowledge. | Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Reporting directly to the Executive Director of Marketing, the marketing leader will help develop and deliver Revolution Medicine’s marketing plans for one of the company’s lead KRAS programs in preparation for anticipated launches. You will work within the Commercial team to define the marketing strategy and tactically deliver critical marketing activities on the Commercial roadmap, for example, market research and patient journey mapping, branding, messaging and content delivery. You’ll collaborate with cross functional teams to provide a commercial marketing perspective on clinical, medical affairs, and market access initiatives. You will grow your team to support expanding marketing needs. This position is based out of our headquarters in Redwood City, CA. Partners to shape the strategic marketing plan and oversee launch readiness initiatives based on deep customer insight; develop branding, positioning, messages, story flow and creative imagery to prepare for and deliver successful oncology product launches. Leads the development and implementation of the therapeutic focused promotional platform (e.g., messaging, market research initiatives, unbranded website etc.). Prioritizes, develops, and implements promotional and disease education tactics (including print and digital promotions, peer-to-peer programming, and key customer marketing initiatives) that establish value with our customers and contribute to achieving a successful product launch. Leads partner agency and vendor relationships and workflow. Operates as ambassador of the company, establishing organization as trusted member of the healthcare community to all relevant stakeholders (Patients, HCPs, Payers, Policy makers, Industry peers). Develops the Customer Marketing Team to understand the needs of the top institutions, key opinion leaders, the competitor landscape and other important healthcare providers to optimize promotional approach, selling tools, and educational programming. Demonstrates the ability to quickly understand complex markets, disease states, competitive landscapes, and relevant market and managed care dynamics. Establishes a strong relationship with medical affairs, and eventually, the sales team and other field-based commercial teams to ensure optimal execution; partner with Sales Training to develop a comprehensive and effective training plan. Participates in cross-functional teams as marketing lead to gather input for functional activities, and ensure alignment with marketing messaging, e.g., with clinical development, medical affairs, and investor relations. Ensures strategic and tactical plans meet compliance and regulatory guidelines and company policies. Delivers marketing operating expenses within budget. Travels as needed. Other duties as assigned. Required Skills, Experience and Education: Bachelor’s degree required (MBA preferred) with at least 12+ years of progressive commercial experience in a biotechnology and/or pharmaceutical company. Successful history of developing and executing the marketing Experience in leading the launch of new products. Demonstrated ability to derive insights/analytics leading to the development of innovative marketing strategies. Strong leadership, with the ability to work well cross-functionally and influence across an organization at all levels. Excellent organizational skills and an ability to prioritize effectively to deliver results within reasonably established timelines. Ability to represent Revolution Medicines well externally: strong interpersonal skills including verbal and written communication. Entrepreneurial mindset, with a tolerance for ambiguity, and a passion for helping cancer patients. Preferred Skills: Proven experience in a smaller, rapidly growing, company. Targeted oncology product experience strongly preferred. Sales experience and ideally sales or field leadership. #LI-Remote #LI-JW1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range $244,000—$305,000 USD

Lead global oncology marketing strategies, oversee product launches, and drive brand positioning and differentiation. | Requires 15+ years in biotech/pharma marketing, proven global product launch success, and leadership in competitive markets. | This a Full Remote job, the offer is available from: United States Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Reporting directly to the Senior Vice President, Global Commercial Development, this newly created role will serve as a leader for continuing to build and drive our global oncology marketing capabilities, including disease area strategy, launch strategy, lifecycle planning, and portfolio differentiation. Candidates should be passionate about building high-performing teams, leading cross-functional collaboration, and contributing as both a strategic leader and hands-on driver in a growing organization. This position is primarily remote with travel required for scientific and team meetings. Specifically, you will be responsible for: • Partner across the company including with clinical development, medical affairs, market access, to drive disease area strategy, shape brand strategies across disease area leadership team and product teams. • Ensure global readiness to drive successful launch planning, commercialization, and performance tracking across the U.S. and key ex-U.S. markets. • Lead a team to design and execute global disease area strategy, brand strategies, including branding, positioning, messaging, and value propositions that guide regional affiliates and align with long-term portfolio goals. • Translate scientific and market insights into compelling strategies, launch narratives, and execution plans; effectively communicating recommendations and leading strategic discussions with global and regional stakeholders. • Develop and refine global brand plans, including revenue and patient forecasts, to inform investment decisions, lifecycle strategies, and portfolio prioritization. • Partner with Marketing, Sales, Market Access, and Medical Affairs to align on integrated brand planning, optimize execution across touchpoints, and ensure consistent messaging worldwide. • Drive excellence in global launch execution: creating launch frameworks, ensuring best practices are shared across affiliates, and monitoring progress to anticipate and resolve challenges. • Identify and manage external agencies, vendors, and partners to deliver impactful global campaigns, educational initiatives, and engagement platforms. • Serve as a trusted resource to executive leadership in identifying opportunities to maximize commercial value, expand indications, and differentiate in competitive markets. • Bring innovation and new capabilities to global marketing—collaborate with IS Commercial to integrate digital, omnichannel, and data-driven approaches to build a best-in-class commercial function. • Provide coaching to lead and develop direct reports to become a highly effective team. • Up to 50% of travel required. Required Skills, Experience and Education: • Bachelor’s degree required (MBA preferred) with at least 15+ years of progressive commercial experience in a biotechnology and/or pharmaceutical company including strategic marketing and ideally sales. • Proven success of developing and executing global marketing strategy. • Experience in leading the global launch of new product in competitive spaces. • Demonstrated ability to derive insights/analytics leading to the development of innovative marketing strategies. • Strong leadership, with the ability to lead teams, work well cross-functionally, and influence across the organization to create a clear sense of direction. • Excellent organizational skills and an ability to prioritize effectively to deliver results within reasonably established timelines. • Ability to represent Revolution Medicines well externally: strong interpersonal skills including verbal and written communication. • Entrepreneurial mindset, with a tolerance for ambiguity, and a passion for helping cancer patients. Preferred Skills: • Experience with an oncology launch is desired. • Prior experience in a smaller, rapidly growing, company. • Experience in gastrointestinal or lung cancers preferred. #DNI The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range $294,000—$367,000 USD This offer from "Revolution Medicines" has been enriched by Jobgether.com and got a 82% flex score.

Lead global oncology marketing strategies, launch planning, and portfolio differentiation, collaborating across functions and managing external partners. | Requires 15+ years in biotech/pharma marketing, proven success in global product launches, and experience in oncology, preferably with a scientific or pharmaceutical background. | Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Reporting directly to the Senior Vice President, Global Commercial Development, this newly created role will serve as a leader for continuing to build and drive our global oncology marketing capabilities, including disease area strategy, launch strategy, lifecycle planning, and portfolio differentiation. Candidates should be passionate about building high-performing teams, leading cross-functional collaboration, and contributing as both a strategic leader and hands-on driver in a growing organization. This position is primarily remote with travel required for scientific and team meetings. Specifically, you will be responsible for: Partner across the company including with clinical development, medical affairs, market access, to drive disease area strategy, shape brand strategies across disease area leadership team and product teams. Ensure global readiness to drive successful launch planning, commercialization, and performance tracking across the U.S. and key ex-U.S. markets. Lead a team to design and execute global disease area strategy, brand strategies, including branding, positioning, messaging, and value propositions that guide regional affiliates and align with long-term portfolio goals. Translate scientific and market insights into compelling strategies, launch narratives, and execution plans; effectively communicating recommendations and leading strategic discussions with global and regional stakeholders. Develop and refine global brand plans, including revenue and patient forecasts, to inform investment decisions, lifecycle strategies, and portfolio prioritization. Partner with Marketing, Sales, Market Access, and Medical Affairs to align on integrated brand planning, optimize execution across touchpoints, and ensure consistent messaging worldwide. Drive excellence in global launch execution: creating launch frameworks, ensuring best practices are shared across affiliates, and monitoring progress to anticipate and resolve challenges. Identify and manage external agencies, vendors, and partners to deliver impactful global campaigns, educational initiatives, and engagement platforms. Serve as a trusted resource to executive leadership in identifying opportunities to maximize commercial value, expand indications, and differentiate in competitive markets. Bring innovation and new capabilities to global marketing—collaborate with IS Commercial to integrate digital, omnichannel, and data-driven approaches to build a best-in-class commercial function. Provide coaching to lead and develop direct reports to become a highly effective team. Up to 50% of travel required. Required Skills, Experience and Education: Bachelor’s degree required (MBA preferred) with at least 15+ years of progressive commercial experience in a biotechnology and/or pharmaceutical company including strategic marketing and ideally sales. Proven success of developing and executing global marketing strategy. Experience in leading the global launch of new product in competitive spaces. Demonstrated ability to derive insights/analytics leading to the development of innovative marketing strategies. Strong leadership, with the ability to lead teams, work well cross-functionally, and influence across the organization to create a clear sense of direction. Excellent organizational skills and an ability to prioritize effectively to deliver results within reasonably established timelines. Ability to represent Revolution Medicines well externally: strong interpersonal skills including verbal and written communication. Entrepreneurial mindset, with a tolerance for ambiguity, and a passion for helping cancer patients. Preferred Skills: Experience with an oncology launch is desired. Prior experience in a smaller, rapidly growing, company. Experience in gastrointestinal or lung cancers preferred. #DNI The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range $294,000—$367,000 USD

Lead and oversee global regulatory submissions and processes to support growth and compliance in a biotech setting. | Extensive experience in regulatory operations within biotech or pharma, with deep knowledge of submission planning, global frameworks, and systems like Veeva RIM. | Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: The Director of Regulatory Operations will lead and be accountable for global regulatory submissions execution, submission-related policies, and end-to-end regulatory processes that support growth and increased portfolio complexity. This position offers the opportunity to strengthen and mature submissions operations through clear process ownership, procedural rigor, and operational excellence. Reporting to the Head of Regulatory Operations, this role serves as a strategic leader within Regulatory Operations, contributing to functional direction, capability planning, and continuous improvement while maintaining strong executional accountability. Success in this role requires the ability to execute while building, work effectively in a dynamic and highly collaborative environment, and remain flexible and adaptive as priorities evolve. Provide operational leadership and accountability for global regulatory submissions across all application types, with strategic input to support increasing submission volume, portfolio expansion, and organizational growth. Advance cross-functional initiatives that enhance the department’s effectiveness and support broader Regulatory objectives. Translate regulatory strategies into executable submission plans, timelines, and resource models. Provide oversight for teams responsible for planning, preparing, publishing, submitting, and archiving global regulatory dossiers. Lead and mentor a submissions-focused team and oversee external vendors to ensure timely, compliant, and high-quality regulatory publishing. Communicate complex issues clearly, providing solutions that balance compliance with the demands of scale. Drive the development, optimization, and implementation of procedures, training, and documentation to support compliant and efficient submission operations. Define, own, and maintain regulatory submissions–related SOPs, work instructions, job aids, standards, policies, and best practices to ensure consistent execution across programs and regions. Drive continuous improvement of submission processes to reduce cycle times, increase predictability, and improve quality. Ensure alignment of submission processes with Quality systems and inspection-readiness expectations. Partner closely with Medical Writing, Regulatory Affairs, Quality, Clinical Operations, and external partners to ensure seamless handoffs and role clarity across the submission lifecycle. Provide clear operational guidance and training to cross-functional contributors involved in submissions. Partner with the Regulatory Systems lead by providing business requirements, operational input, and process alignment to ensure systems effectively support submissions execution, without serving as system owner or administrator. Required Skills, Experience and Education: Bachelor’s degree in a life science, or related field with 15+ years of experience in the biotechnology, pharmaceutical, or medical device industry, with at least 8 years focused on Regulatory Affairs/Operations and Veeva RIM systems (administration, configuration, and optimization). Proven leadership in developing and executing regulatory operations strategy within global biotech or biopharma organizations. Deep expertise in submission planning, global regulatory frameworks, eCTD standards, and Health Authority requirements. Strong understanding of regulatory systems from a business process and end-user perspective. Strong project management skills, with the ability to oversee multiple priorities and deliver results in a dynamic environment. Clear and persuasive communicator across technical and business stakeholders. Effective collaborator with the ability to influence and align cross-functional teams. Strategic thinker with a practical problem-solving mindset and long-term business orientation. Committed to developing high-performing teams and fostering a culture of accountability and continuous improvement. Experience leading process improvement initiatives in a compliance-focused environment. Preferred Skills: Seasoned people manager. Adept in regulatory publishing; capable of serving as a backup publisher. Proficient in Smartsheet for project tracking and collaboration. #LI-Hybrid #LI-JC1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range $211,000—$264,000 USD

Lead and develop the pharmacovigilance quality management system, ensuring compliance with global regulations, and foster a culture of safety and continuous improvement. | Extensive experience in pharmacovigilance or related pharmaceutical/biotech field, with proven leadership, regulatory interaction skills, and in-depth knowledge of global PV regulations. | Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: We are seeking a skilled and experienced Executive Director (ED) of Global Patient Safety (GPS) Quality and Compliance to join our dynamic team. The ED GPS Quality and Compliance is responsible for the strategy, development, oversight, and execution of the pharmacovigilance quality management system (PV-QMS) within the organization. This role ensures the safety of patients and the overall positive benefit-risk of RevMed pharmaceutical products by driving compliance with global pharmacovigilance regulations and fostering a culture of safety and vigilance. The responsibilities of this role include oversight of the PV-QMS , PV training strategy, PV controlled documentation, inspection and audit management, ensuring inspection readiness, Corrective Action Preventive Action (CAPA) management, Quality Assurance (QA), and maintenance of Good Clinical Practice (GCP), and Good Pharmacovigilance Practices (GVP) in partnership with GPS management, QA, and staff. The ED of GPS Quality and Compliance will help to develop and implement the pharmacovigilance system in support of Revolution Medicine’s research and development and marketed products. The successful candidate will have innate leadership and organization skills, technical expertise in the field, and experience in organizing and overseeing pharmacovigilance quality, compliance, and training. As an ED, you will work closely with the GPS management team to develop and build out the PV-QMS as an important component of a fully compliant pharmacovigilance system; you will be responsible for GCP/ICH quality leadership, strategic development of quality initiatives and support a quality focused culture in the execution of the PV-QMS. This critical role will require strategic thinking, expert knowledge of global PV regulations (i.e. GCP, GVP), the ability to influence and communicate ideas effectively, results orientation, collaboration with cross-functional teams, technical expertise, and vendor management skills to ensure compliance with regulatory requirements to safeguard patient well-being. Additional responsibilities include: In cooperation with the GPS leadership team, co-develop and implement the global pharmacovigilance quality management system strategy in alignment with the company’s mission and objectives. Develop and implement a PV training strategy that ensures compliance and ensures high quality and consistent performance. Provide strategic direction and leadership to GPS and cross-functionally. Lead, mentor, and coach GPS staff ensuring high quality compliance support following best practices, global regulations, and internal requirements. Oversee the resourcing, budget, and management of pharmacovigilance contract research organizations (PV CROs) in quality and compliance activities. Author and contribute to the preparation of controlled documentation required by health authorities for management of the QMS. Develop and maintain relationships across Revolution Medicines, particularly in Clinical Operations, Clinical Development, Clinical Data Science, Regulatory Affairs, Quality Assurance, Medical Affairs, and other departments as appropriate to ensure a globally compliant QMS. Collaborate to create robust processes to maintain compliance with safety requirements related to safety science processes. Work with the EU Qualified Person Responsible for Pharmacovigilance (EU-QPPV) to ensure European compliance as applicable. Responsible for ensuring inspection readiness for global inspections by ensuring all processes and training reflect global regulatory requirements. Manage all inspections that include PV and ensure completion and tracking of CAPAs. Foster a culture of safety, compliance, and continuous improvement within the pharmacovigilance function and broadly across the organization. Ensure compliance with global pharmacovigilance regulations and standards, including FDA, EMA, PMDA, ICH, and other relevant regulatory bodies. Lead the GPS response to regulatory inquiries and inspections related to pharmacovigilance inspections. Lead the development and maintenance of a pharmacovigilance quality system in line with global regulations (i.e. GCP, GVP) enabling demonstration of quality, effectiveness, and control. Partner with pharmacovigilance systems personnel in the development and implementation of advanced safety data analytics in support the PV-QMS. Build, mentor, and lead a high-performing global pharmacovigilance team. Promote continuous professional development and ensure the team is equipped with the latest knowledge and skills in pharmacovigilance. Provide regular updates to senior leadership on the status of pharmacovigilance system effectiveness, and regulatory compliance. Ensure clear and effective communication of safety information to internal and external stakeholders. Required Skills, Experience and Education: RN or Bachelor’s degree in biological sciences or health related field required. Advanced degree in Pharmacy, or a related field (PharmD, PhD: preferred). Minimum of 15+ years of experience in pharmacovigilance or related field within the pharmaceutical or biotechnology industry. Minimum of 10+ years of project and line management experience; strong people management skills, willingness to help others, and ability to deal with ambiguity. Proven track record of leadership in global pharmacovigilance environments. Experience and success in interacting with Regulatory Authorities (i.e. FDA, EMA). In-depth knowledge of global pharmacovigilance regulations and guidelines (i.e. ICH, GxP) Strong analytical and strategic thinking, problem-solving, and decision-making skills. Excellent communication, collaboration, and team management abilities, enabling exertion of strong and successful influence of senior executives as well as strong external representation for the company. Demonstrated technical expertise in QA/QC. Outstanding emotional intelligence. Proven ability to lead and develop people. Preferred Skills: Experience with development of PV-QMS and key operating metrics enabling demonstration of operational control. Demonstrated ability to manage complex projects and work effectively in a matrixed organization. Proficiency in managing regulatory inspections and interactions. Strong organizational and time management skills, with the ability to prioritize and manage multiple tasks effectively. Excellent influence and collaboration/teamwork capabilities. #LI-Hybrid #LI-GL1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range $265,000—$331,000 USD

Lead global CMC regulatory strategy and execution for small molecule oncology products, ensuring compliance and facilitating global approvals. | Extensive experience in biotech/pharma regulatory affairs, especially CMC for small molecules, with global submission expertise and leadership in a fast-paced, science-driven environment. | Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: We are seeking an accomplished, strategic and execution-oriented leaders, Vice President, Global CMC Regulatory, reporting to SVP of Pharmaceutical Development and Manufacturing (PDM) Regulatory, to lead our global chemistry, manufacturing, and controls (CMC) regulatory strategy and execution across all development programs and commercial assets. This leader will drive regulatory strategy development, lead regulatory interactions, and provide expertise throughout the product lifecycle, from early development to post-approval variations ensuring the timely submission and approval of high-quality CMC regulatory filings to support our company’s pipeline and global growth. The successful candidate will serve as a senior leadership role within Pharmaceutical Development and Manufacturing (PDM) organization, overseeing CMC regulatory activities and ensuring alignment with health authority expectations globally (FDA, EMA, PMDA, NMPA, etc.). The role requires expertise in small molecule pharmaceutical development and manufacturing, an understanding of the oncology development lifecycle, and the ability to thrive in a dynamic, fast-paced environment. Responsibilities: Global CMC Regulatory Strategy Develop and execute global CMC regulatory strategies in alignment with product development plans for clinical and commercial programs / marketed products. Provide strategic CMC regulatory leadership to support global filings, approvals, and post-approval lifecycle management. Proactively identify and manage CMC regulatory risks, anticipate challenges and develop mitigation strategies to support business objectives and ensure global alignment and compliance. Health Authority Engagement Serve as the primary CMC regulatory interface with global health authorities, including FDA, EMA, EU National Competent Authorities, and PMDA. Lead and support CMC-related regulatory meetings, scientific advice, and responses to health authority questions. Regulatory Submissions & Lifecycle Management Oversee the preparation, review, and submission of high-quality CMC sections for NDAs, MAAs, J-NDAs, and global post-approval variations. Ensure consistency, compliance, and scientific rigor across global CMC regulatory filings. Provide strategic oversight for post-approval changes, including site changes, process improvements, and supply chain optimization. Interpret and apply evolving CMC regulatory requirements and guidance globally. Cross-Functional Collaboration Partner closely with Drug Substance, Drug Product, Analytical Development and QC, Manufacturing, Supply Chain, Quality, and Program Management to align regulatory strategy with technical and operational plans. Act as a regulatory subject matter expert for tech transfer, global site registration, comparability protocols and control strategy development. Team Development & Leadership Build, mentor, and lead a high-performing global CMC regulatory team, fostering accountability, development, and innovation. Manage external regulatory consultants and regional partners to ensure consistent global execution and local expertise. Required Skills, Experience and Education: Advanced degree (PhD, PharmD, or MS) in Chemistry, Pharmaceutical Sciences or related scientific discipline. Minimum of 18 years of experience in the biotech/pharmaceutical industry, with at least 10 years in CMC regulatory affairs and global submission experience. Demonstrated success leading global CMC regulatory strategies for small-molecule products. Proven success scaling CMC regulatory function in a public, late-stage biotech/pharma company. Deep understanding of global regulatory frameworks and guidelines (FDA, ICH, EMA, PMDA, NMPA, etc.). Strong leadership and collaboration skills with a demonstrated ability to work cross-functionally and influence stakeholders at all levels. Strong written and verbal communication skills, with the ability to clearly articulate regulatory strategy and risk. Ability to thrive in a fast-paced, matrixed, and science-driven environment. Preferred Skills: Experience with oncology development programs and familiarity with accelerated or expedited pathways. Experience with Japan-specific CMC regulatory requirements (e.g., consultations, GQP/GMP compliance, J-NDA format). Exposure to lifecycle management activities including global variations, site changes, and supply chain adaptations. #LI-Hybrid #LI-GL1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range $294,000—$367,000 USD

Provide strategic legal guidance on commercialization, regulatory, and compliance issues for a biotech company. | JD with 15+ years in biotech or pharmaceutical legal leadership, deep FDA regulatory knowledge, and experience supporting product launches. | Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. Reporting to the Deputy General Counsel, the Executive Director or Vice President, Healthcare Law (depending on experience) will provide strategic legal guidance related to the Company’s planned commercialization activities, including related to market access, patient access programs, distribution and licensing, and regulatory submissions. The successful candidate will bring proven experience working at a publicly traded life sciences organization, with demonstrated success in driving legal cross-functional strategy. Location: Redwood City, CA on a hybrid basis. Remote candidates will be considered with the understanding that a regular in-office presence is required in order to collaborate with the team and other stakeholders. Key Responsibilities: • Serve as a legal advisor to members of the executive team on a wide range of commercialization issues with broad enterprise impact. • Serve as legal representative for Commercialization and Medical-related committees and teams, including promotional review, medical materials, and educational and charitable grants. • Serve as the lead counsel for healthcare regulatory law, including the FDCA and related Regulations, and Guidance Documents, fraud and abuse laws and guidance (Anti-Kickback Statute, False Claims Act, OIG Guidance and Advisory Opinions), and federal and state transparency and reporting laws. • Provide legal counsel on regulatory interactions with FDA and other regulatory authorities. • Coordinate with Compliance sub-function to operationalize compliance in commercialization activities, including related to promotional materials, scientific exchange, and interactions with HCPs. • Provide strategic legal advice related to patient support programs, patient hubs, market access, pricing, reimbursement, and distribution via different channels and interest groups (e.g., specialty distributors, specialty pharmacies, PBMs, GPOs, 340B hospitals)and oversee commercial contracting. • Advise on issues regarding clinical trials, including related to CT.gov compliance, data privacy, interactions with clinical sites and investigators, CTA contracting and ICFs. • Proactively monitor emerging healthcare and regulatory law trends, such as Biosecure, IRA, and MFN pricing, and assess and communicate their impact on RevMed. • Build and manage teams in a dynamic high-growth environment. Qualifications & Key Attributes: • JD degree with 15+ years of legal experience, including leadership experience at a commercial stage biotech or pharmaceutical company. • Deep familiarity with FDA advertising and promotion compliance. • Strong contracting acumen with ability to advise clinical, medical, and commercial teams. • Exceptional executive communication, stakeholder management, and negotiation skills; ability to convey complex legal risks in clear, business‑centric terms. • Demonstrated experience shaping legal strategy across multiple substantive areas. • Experience supporting product launches. • Experience hiring and developing legal teams. • Collaborative, flexible, positive and pragmatic work style with excellent written and verbal communication skills. • Excellent interpersonal and collaborative skills that inspire trust and alignment across functions. • Ability to maintain confidentiality and operate with high ethical standards and professionalism. • Ability to thrive in a collaborative team setting and a desire to be innovative in rapidly evolving and fast-paced corporate environment. • Champions RevMed’s values (Tireless Commitment to Patients, Transformative Science, Exceptional Together, Total Integrity, Inclusiveness and Fairness). Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Lead and coordinate global drug development projects, manage risks, and ensure efficient execution of clinical programs. | Minimum 8 years in biotech/pharma with 5+ years managing cross-functional development teams, strong knowledge of drug development processes, and proficiency with project management tools. | Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: This is an exciting, high-profile, and highly visible Program Management opportunity to advance a first-in-Class RAS(ON) Inhibitor through clinical development. The ideal candidate is a very proficient and self-motivated program manager with a solid understanding of drug development. The Director, Program Management partners with the Project Team Leader (PTL) on the translation of program strategy into an efficient execution plan; they understand the competitive landscape and clinical context to manage the cross-functional dependencies and connections. They understand the breadth of cross-functional activities and can foster productive collaborations to ensure successful execution. Overall, the Director, Program Management makes things happen via productive collaborations in an organization that is rapidly developing its capabilities and infrastructure. They not only care about the outcomes but how we get there. The successful candidate will draw upon their experience to: Partner with the PTL in defining program strategy, stakeholder management, and overall program leadership topics. Establish and maintain functionally integrated project plan and project assumptions (accounting for goals, key objectives, deliverables, risks) to enable accurate project, financial and portfolio analyses for business planning processes. Ensure identification and management of program risks; working with subject matter experts to construct appropriate mitigation plans. Evaluate alternative development scenarios (comprising costs, timelines, risks, and project strategy) during progression of the program through stage gates and as per business need. Lead the global development team through the preparation and update of key project documents and communications. Lead an efficient information flow within the global cross-functional project team, and internal advisory & governance bodies. Demonstrate effective meeting and information management including prioritizing the right topics for discussion, ensuring the objectives of the meeting are achieved, communicating decisions to key stakeholders and ensuring that action items are assigned and completed in a timely manner. Serves as the owner of project team information including the project plan, budget and program assumptions as approved by PRG and the Senior Leadership Team. Partner with the PTL to ensure the team achieves and maintains a high-level of sustainable performance. Apply drug development expertise to coach and mentor project team members to ensure efficient and effective project team operation. Identify, recommend, and implement opportunities for streamlining team and business processes. Participate in establishment and implementation of project management systems and best practices. Coach and mentor members of the Program Management team to ensure a strong bench of future leaders. Support new corporate development activities or other initiatives supporting department, portfolio, or corporate needs. Required Skills, Experience and Education: B.A. or BSc. in Life Sciences and at least 8 years’ experience in the biotech/pharmaceutical industry with at least 5 years’ direct development project management experience managing cross-functional global development teams. Broad knowledge of the clinical drug development process and regulations, coupled with strong proficiency in project management practices, tools, and methodology. Expertise in developing and managing project scope, deliverables, risk & resource requirements including, Schedule / Timeline management, and Risk management. Excellent interpersonal skills, including clear, succinct, and timely communication and proven ability to foster important relationships with key stakeholders. Outstanding verbal and written communication skills with the ability to summarize complex information into simple concepts; has the ability to effectively interact across team line functions as well as with external key stakeholders. Proven track record of good decision making and exercising sound judgment. Experience using Project Management software to manage project timelines and resources (e.g., MS Project, SmartSheet, OfficeTimeline, and OnePager Pro etc.). Strong computer proficiency with MS Office suite, SharePoint and similar document archiving systems. Preferred Skills: MSc. or MBA or Ph.D. in Life Sciences a plus PMP (Project Management Professional) or other PM certification or equivalent is a plus. Experience in Oncology therapeutic area is strongly preferrable. #LI-Hybrid #LI-YG1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range $211,000—$264,000 USD

Provide statistical leadership and support for late-stage oncology clinical development, including study design, analysis, and regulatory documentation. | Requires a Ph.D. or M.S. in Statistics/Biostatistics with extensive experience in biotech/pharma, especially in oncology trials, and proficiency in SAS and R. | Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Playing a critical role as a lead statistician for clinical program(s) and studies in clinical late-stage development and the subject matter expert (SME) in Biostatistics within Quantitative Sciences function, this position is to provide statistical leadership and support for clinical development strategy and clinical studies through product life cycle. • Provide statistical support and strategic input to clinical development plans, proof of concept criteria, and team’s preparation for company governance reviews. • Represent Biostatistics function on cross-function teams and serve as a lead statistician for oncology studies. • Collaborate with various functions on study design and planning, protocol development, statistical analysis plan and analysis specifications. • Provide statistical support for study protocol development, analysis plan and specification. • Plan and prepare independent data monitoring committee (DMC), coordinate with independent statistical data analysis center for DMC and study team for periodic DMC reviews. • Collaborate with data management and clinical operations over the course of clinical studies to provide statistical input to study conducts and database development as well as data collection and cleaning activities. • Collaborate with statistical programming to ensure that appropriate programs and documentations are being developed for datasets development and outputs generation, and ensure the statistical analyses specified in scientific protocols and/or analysis plans are conducted appropriately. • Provide statistical input and leadership to the development of global health authority documents, regulatory interaction and response to health authority submissions. • Provide statistical support for clinical publications, assist in data interpretation to ensure consistency and accuracy in data presentation. • Drive and lead department initiatives, best practices, and guidelines. • Keep abreast in new developments in statistics, drug development, and regulatory guidance and share knowledge with functional and cross-functional team members. Required Skills, Experience and Education: • Ph.D. or M.S. in Statistics/Biostatistics, a minimum of 8 years (for Ph.D.) and 12 years (for M.S.) of experience in the biotech/pharma industry as a statistician. Level will be determined based on the relevance of experience. • Hands-on experience in design and analysis of late-stage oncology trials is a must. • Ability to work independently and within a team. • Solid knowledge in ICH and other regulatory requirements related to biostatistical activities and clinical trials. • Excellent verbal and written communication skills are required. • Good interpersonal and project management skills are essential. • Proficiency in SAS and/or R. Preferred Skills: • Active participation in NDA/BLA filing through label negotiations is desirable. The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy . For additional information, please contact privacy@revmed.com . Base Pay Salary Range $211,000 — $264,000 USD

Lead biomarker operations for Phase III clinical trials, including protocol planning, vendor management, and data tracking. | Requires 7+ years in clinical research or diagnostic labs, experience with biomarker and CDx operations, and proficiency in project management tools. | Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Playing a critical role as a Senior Specialist Biospecimen Operations within Translational Medicine function, the position will be providing biomarker operational expertise in, developing scope of work, and maintaining effective working relationships with cross-functional teams for phase three clinical trials. • Lead biomarker operations across clinical studies, including protocol planning, testing strategy, data management, and documentation. • Collaborate with Biomarker Leads and Clinical Operations on protocol, ICF, eCRF, and eTMF reviews. • Oversee central lab activities: budget and SOW reviews, lab manual and site requisition form reviews. • Partner with CQA for initiating new vendor qualification to conducting biomarker testing. • Manage relationships with central/specialty labs and Biobank, initiate study contracts, coordinate meeting discussions, review invoices, and issue resolutions. • Develop and maintain tracking systems for sample logistics and data generation. • Contribute to SOP development and biomarker program initiatives. • Support TM deliverables including interim analyses, CSRs, and regulatory filings. • Help manage biomarker operations budgets, identify and mitigate sample/data handling risks. • Independently lead biomarker operations for Phase III oncology trials. • Oversee vendor selection and participate in audits. • Engage cross-functional teams and provide Biomarker metrics and updates. • Responsible for reviewing ICFs and addressing inquiries from ECs and/or IRBs related to Biomarker components. • Collaborate closely with Pharmacokinetic leads to support PK operations and ensure all PK deliverables are met according to project requirements. • Experience in diagnostic operations supporting CDx and sPMA regulatory filing • Utilize IRT systems and present biomarker strategies to senior leadership. Required Skills, Experience and Education: • Life sciences degree (BS or MS) in scientific, medical, healthcare, or related discipline. • 7+ years related professional experience in a clinical research setting, clinical/diagnostic laboratory. • Should have experience mentoring team members. • Prior experience in clinical biomarker and CDx operations in phase three clinical trials is highly desirable. • Excellent scientific and business communication skills, strong interpersonal/collaboration skills, and planning skills. • Should be proficient in Microsoft Excel, Microsoft PowerPoint applications. • Experience in using Project Management tools is highly desired. • Ability to think critically and creatively and be able to work independently to determine appropriate resources for resolution of problems. • Ability to multi-task and thrive in a fast-paced innovative environment. • A great teammate, who listens effectively and invites response and discussion. • Commitment to Revolution Medicines’ Core Values: Tireless Commitment to Patients, Transformative Science, Exceptional Together, Total Integrity, Inclusiveness and Fairness. Preferred Skills: • Should be proficient in Microsoft Excel, Microsoft PowerPoint applications. • Experience in using Project Management tools is desirable. • Experience in using LIMS Sample Management tool is desirable. • Experience with next-generation sequencing (NGS) methods for RAS mutation analysis is desirable. The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy . For additional information, please contact privacy@revmed.com . Base Pay Salary Range $143,000 — $178,000 USD

Design and implement enablement programs, tools, and processes to support clinical development teams, ensuring effective execution and adoption. | Over 10 years of experience in project and change management within biotech/pharma environments, with strong communication and stakeholder management skills. | Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: The Sr Manager Process Enablement is an internal project manager with a consultant mindset and hands-on approach. This is an execution-focused role that strengthens the effectiveness, scalability, and consistency of the Development & Clinical Sciences (DCS) organization. This role partners closely with the Development Leadership Team, functional teams and program teams to design and implement programs, tools, and processes that enable growth and evolving our ways of working. The role is ideal for a Senior Manager–level professional who thrives on execution and has strong project leadership, communication and change management experience. Responsibilities: Enablement Programs & Tools Design and deploy practical solutions (e.g., templates, toolkits, playbooks, workflows) that enable DCS teams in their day-to-day work. Ensure solutions are practical, scalable, and embedded into existing processes. Partner with subject-matter experts to translate complex DCS practices into clear, usable resources. Conduct needs assessment to evolve business processes and drive operational performance. Execution & Delivery Implement frameworks, tools, and processes that support consistent execution across DCS functions. Own day-to-day planning, coordination, and delivery of project initiatives, ensuring timelines, quality, and outcomes are met. Data, Insights & Continuous Improvement Track adoption and effectiveness of enablement initiatives using defined metrics and stakeholder feedback. Identify capability gaps and execution challenges; drive continuous improvement actions. Provide leaders with clear visibility into the capabilities readiness and progress. Stakeholder Partnership & Change Enablement Partner with DCS leaders to support consistent implementation and change adoption. Identify potential resistance points and execute mitigation actions to support engagement. Coordinate closely with functional partners to ensure aligned execution. Required Skills, Experience and Education: 10+ years’ experience in change management, project management or consulting with at least 3 years in pharma/ biotech environment. BS/BA degree in life science, business management, organizational psychology or related discipline. Experience leading complex organizational change efforts. A thorough understanding of the clinical development process within biopharma. Excellent verbal and written communication skills with the ability to distill the key points into a succinct summary. Strong interpersonal skills to interact daily with diverse cross-functional internal and external stakeholders. Comfortable providing counsel to senior leaders. Self-motivated and able to work independently to execute strategic direction. Preferred Skills: MSc., MA, MBA or Ph.D. a plus. Proactive, and collaborative team-player with high energy to keep pace with our growing and evolving company environment. Experience building professional working relationships at all levels within and across the organization. Adaptable, proactive personality style that can prioritize, quickly adapt to changing conditions. Able to function independently in a fluid environment under tight timelines. Advanced skills with MS Office software (Excel, PowerPoint, Word) and Smartsheet. #LI-Hybrid #LI-JC1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range $164,000—$205,000 USD

Design and implement enablement programs, tools, and processes to support clinical development teams, ensuring effective execution and continuous improvement. | Over 10 years of experience in project or change management, preferably within pharma/biotech, with strong communication, stakeholder management, and organizational change skills. | Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: The Sr Manager Process Enablement is an internal project manager with a consultant mindset and hands-on approach. This is an execution-focused role that strengthens the effectiveness, scalability, and consistency of the Development & Clinical Sciences (DCS) organization. This role partners closely with the Development Leadership Team, functional teams and program teams to design and implement programs, tools, and processes that enable growth and evolving our ways of working. The role is ideal for a Senior Manager–level professional who thrives on execution and has strong project leadership, communication and change management experience. Responsibilities: • Enablement Programs & Tools • Design and deploy practical solutions (e.g., templates, toolkits, playbooks, workflows) that enable DCS teams in their day-to-day work. • Ensure solutions are practical, scalable, and embedded into existing processes. • Partner with subject-matter experts to translate complex DCS practices into clear, usable resources. • Conduct needs assessment to evolve business processes and drive operational performance. • Execution & Delivery • Implement frameworks, tools, and processes that support consistent execution across DCS functions. • Own day-to-day planning, coordination, and delivery of project initiatives, ensuring timelines, quality, and outcomes are met. • Data, Insights & Continuous Improvement • Track adoption and effectiveness of enablement initiatives using defined metrics and stakeholder feedback. • Identify capability gaps and execution challenges; drive continuous improvement actions. • Provide leaders with clear visibility into the capabilities readiness and progress. • Stakeholder Partnership & Change Enablement • Partner with DCS leaders to support consistent implementation and change adoption. • Identify potential resistance points and execute mitigation actions to support engagement. • Coordinate closely with functional partners to ensure aligned execution. Required Skills, Experience and Education: • 10+ years’ experience in change management, project management or consulting with at least 3 years in pharma/ biotech environment. • BS/BA degree in life science, business management, organizational psychology or related discipline. • Experience leading complex organizational change efforts. • A thorough understanding of the clinical development process within biopharma. • Excellent verbal and written communication skills with the ability to distill the key points into a succinct summary. • Strong interpersonal skills to interact daily with diverse cross-functional internal and external stakeholders. • Comfortable providing counsel to senior leaders. • Self-motivated and able to work independently to execute strategic direction. Preferred Skills: • MSc., MA, MBA or Ph.D. a plus. • Proactive, and collaborative team-player with high energy to keep pace with our growing and evolving company environment. • Experience building professional working relationships at all levels within and across the organization. • Adaptable, proactive personality style that can prioritize, quickly adapt to changing conditions. • Able to function independently in a fluid environment under tight timelines. • Advanced skills with MS Office software (Excel, PowerPoint, Word) and Smartsheet. The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy . For additional information, please contact privacy@revmed.com . Base Pay Salary Range $164,000 — $205,000 USD

Lead and execute marketing strategies for oncology products, including brand planning, launch readiness, and cross-functional collaboration. | 15+ years of progressive experience in biotech/pharmaceutical marketing, proven success in product launches, and strong leadership skills. | Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Reporting directly to the VP, US Field and Marketing, the marketing leader will lead and deliver Revolution Medicine's marketing plans for the company's lead RAS programs in preparation for anticipated launches. You will work within the Commercial team to define marketing strategy and tactically deliver critical marketing activities on the Commercial roadmap, for example, KOL strategy and influence mapping, branding, messaging and content delivery. You'll collaborate with cross functional teams to provide a commercial marketing perspective on clinical, medical affairs. Your team will support expanding marketing and PDAC needs. This position is based out of our headquarters in Redwood City, CA. • Operate as ambassador of the company, establishing organization as trusted member of the healthcare community to all relevant stakeholders (Patients, HCPs, Payers, Policy makers, Industry peers). • Lead 3 year Brand Planning for PDAC Portfolio. • Lead the development of strategic marketing plans and oversee launch readiness initiatives based on deep customer insight; branding, positioning, messages, story flow and creative imagery to prepare for and deliver successful oncology product launches. • Partner with the field-based Customer Marketing Team with focus on Regional Insights, and understand the needs of the top institutions, key opinion leaders, the competitor landscape, and educational programming. • Define strategic partnerships and execution plan with key business partners (diagnostic companies, EMR partners and advocacy groups). • Lead, mentor, and develop a high-performing team of marketing professionals, fostering a culture of collaboration, accountability, and continuous improvement. • Provide strategic direction and oversight for team priorities, ensuring alignment with organizational goals and effective execution across marketing initiatives. • Prioritize, develop, and implement Omnichannel promotional and disease education tactics (including print and digital promotions, peer-to-peer programming, and key customer marketing initiatives) that establish value with our customers. • Oversee partner agency and vendor relationships and workflow. • Demonstrate the ability to quickly understand complex markets, disease states, competitive landscapes, and relevant market and managed care dynamics. • Establish a strong relationship with medical affairs, and eventually, the sales team and other field-based commercial teams to ensure optimal execution; partner with Sales Training to develop a comprehensive and effective training plan. • Participate in cross-functional teams as marketing lead to gather input for functional activities, and ensure alignment with marketing messaging, e.g., with clinical development, medical affairs, and investor relations. • Ensure strategic and tactical plans meet compliance and regulatory guidelines and company policies. • Deliver marketing operating expenses within budget. • Travel as needed. • Other duties as assigned. Required Skills, Experience and Education: • Bachelor's degree required (MBA preferred) with at least 15+ years of progressive commercial experience in a biotechnology and/or pharmaceutical company including global strategic marketing and ideally sales. • Successful history of developing and executing the marketing strategy Experience in leading the launch of new products. • Proven experience in a smaller, rapidly growing, company. • Demonstrated ability to derive insights/analytics leading to the development of innovative marketing strategies. • Strong leadership, with the ability to work well cross-functionally and influence across an organization at all levels. • Excellent organizational skills and an ability to prioritize effectively to deliver results within reasonably established timelines. • Ability to represent Revolution Medicines well externally: strong interpersonal skills including verbal and written communication. • Entrepreneurial mindset, with a tolerance for ambiguity, and a passion for helping cancer patients. Preferred Skills: • Targeted oncology product experience strongly preferred. The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range $265,000-$331,000 USD

Manage a high volume of site contract agreements from start to finish, ensuring timely and accurate implementation of all contract terms. Support all site contract and budget activities related to clinical trials, while collaborating with various teams to achieve clinical study goals. | Candidates should have a B.S. and 8-10 years of related experience, particularly in oncology and clinical budget negotiation. Strong analytical, negotiation, and communication skills are essential, along with knowledge of FDA regulations and ICH guidelines. | Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Revolution Medicines is seeking a motivated individual Site Contract Manager, who will support all processes related to site contracts and budgets. The individual will be involved with but not limited to drafting, advising, negotiating and executing clinical site agreements. Conducts first round of reviews to ensure final contracts and contract terms are consistent with organizational strategy, delivered by agreed upon timelines, falls within Fair Market Value and in compliance with legal, financial & regulatory requirements. This role is an individual contributor with team leadership responsibilities, reporting into the Associate Director, Site Contracts, Must have previous oncology experience. Responsibilities: Ability to manage a high volume of site contract agreements from start to finish. Help support all site contract and budget activities related to clinical trials. Ensure consistency of contract terms with company policies and goals and best practices to enhance the contracting process. Ensure smooth, timely, and accurate implementation of all contract terms. Support the timely preparation and execution of all site contracts and budgets. Responsible for entering contracts into CMS. Demonstrated experience with clinical budget build/development using (FMV), and historical data (Grant Plan). Strong negotiation of MCTA, ICTAs, CTAs, CSAs, CDAs, other site agreements and budgets with investigator sites (directly or with support where language necessitates), using appropriate templates, guidance, and legal/budget playbooks, liaising with ClinOps, Finance and legal for approval. Provide input for ongoing updates of applicable legal contracts and budget playbooks and templates. Ensure appropriate tracking of various agreements. Effectively escalate/communicate in a timely manner to stakeholders and clinical teams regarding contract issues that could impact project deliverables. Support in process improvement projects and continuous improvement in delivery of Global Contract Management responsibilities. Demonstrate applicable competencies in contract management, critical thinking, highly competent in negotiation and contracting business standards. Assist in the execution of end-to-end process is robust and is established as a way of effectively supporting the needs of key business partners while continuously monitoring and further enhancing service quality, efficiency and effectiveness and lead or support continuous improvement initiatives. Support the contract workflow and collaboration with senior leaders to ensure efficient contract execution and suggest and implement new / more efficient processes as needed. Involved in measuring and reporting metrics and Key Performance Indicators (“KPIs”) for in-scope service deliverables. Participation in team meetings and collaborate with other functional groups within the company to achieve clinical study goals. Ensure contracts and budgets are completed on time, within budget and in compliance with Standard Operating procedures (SOPs), FDA regulations and International Council for Harmonisation (ICH)/ GCP guidelines. Communicate effectively within cross functional project teams at Revolution Medicines. Required Skills, Experience and Education: B.S., 8-10 years equivalent related business/ industry experience. Experience in pharmaceutical, biotech, academia, CROs (Clinical Research Organizations). Strong computer skills: Microsoft office and software to manage contracting. Demonstrated leadership, stakeholder influencing without authority and negotiation skills. Strong knowledge of a wide variety of clinical-related contract types, including, clinical trial site agreements, investigator sponsored trial agreements, research collaboration agreements, consulting agreements and confidentiality agreements. 1 + years experience with clinical budget negotiation. Strong analytical and contract administration skills, verbal and written communication skills, and the ability to interact effectively with internal and external business partners. High degree of dedication, motivation, and ability to work under pressure with a drive for results and the ability to engage and deliver through others. Experience working in a global environment. Strong working knowledge of FDA Regulations, ICH Guidelines and GCPs governing the conduct of clinical trials. Strong problem solving skills with sound technically driven decision-making ability. An innovative team-player with capacity to be effective in a dynamic and fast-paced company environment Oncology experience necessary. Preferred Skills: Big pharma/CRO experience a plus. Grant Plan experience a plus. #LI-Remote #LI-DN1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. Base Pay Salary Range $138,000—$172,000 USD