ECN Operating LLC

Oversee all aspects of clinical trial site operations, including staff management, regulatory compliance, data quality, participant recruitment, and stakeholder communication. | Bachelor’s degree in a healthcare or scientific field, minimum 5 years in clinical research management, strong communication and management skills, proficiency with industry standards and tools. | Position Summary The Site Manager reports directly to the assigned Regional Site Manager and is responsible for the deployment, oversight, and maintenance of Elite Clinical Network (ECN) processes in the conduct of clinical trials. This role includes full accountability for all site staff and operations. The Site Manager is responsible for the daily operational oversight and overall performance of a clinical research site. This role ensures that clinical trials are conducted efficiently, in compliance with regulatory requirements, and in alignment with company objectives. The Site Manager oversees site staff, coordinates resources, monitors key performance indicators, and fosters a high-performing, patient-centric research environment. Roles and Responsibilities: • Manage all aspects of study execution from initiation through close-out to ensure adherence to projected timelines, high-quality protocol execution, and full compliance with internal ECN processes. • Monitor and manage site-level revenue and expenses, ensuring financial targets are achieved. Collaborate with finance and leadership to track study billing, manage budgets, review payment schedules, and control costs to maximize site profitability and financial health. • Create and implement detailed operational plans tailored to each study, including staffing, equipment, resource needs, and timelines, ensuring effective resource allocation and protocol compliance. • Ensure accurate and timely completion of all regulatory reporting in accordance with GCP, ICH guidelines, and applicable local, national, and international regulations. Maintain documentation and audit readiness at all times. • Oversee data integrity through routine documentation review, source verification, and efficiency checks. Ensure accuracy, completeness, and compliance of all collected data with study protocols and regulatory expectations. • Maintain accountability for timely and accurate data entry and reporting. Monitor submission timelines to ensure sponsor and regulatory deadlines are met without exception. • Meet or exceed all participant recruitment and enrollment goals by implementing proactive recruitment strategies and monitoring enrollment performance. • Serve as the primary point of contact for Sponsors, CROs, and vendors, ensuring timely communication, resolution of operational issues, and alignment on study deliverables. • Provide comprehensive training and onboarding for new site staff, ensuring protocol requirements, regulatory guidelines, and site-specific procedures. • Plan and lead regular site team meetings to foster communication, address operational challenges, share study updates, and ensure consistency across clinical and administrative functions. • Collaborate closely with the Regional Site Manager and attend required leadership meetings to ensure alignment of study progress with organizational priorities and performance targets. • Oversee the evaluation, selection, and performance management of research staff to ensure staffing adequacy, team competency, and support for study operations. • Maintain and routinely audit the site’s master training file, including staff certifications, licensure, and training records, to ensure compliance and readiness for inspections. • Develop and maintain collaborative relationships with monitors, project managers, vendors, and sponsor representatives, facilitating streamlined operations and issue resolution. • Develop and maintain assigned source documentation in accordance with protocol specifications, ensuring data quality, consistency, and real-time updates throughout the study lifecycle. • Review monitoring visit follow-up letters promptly, identify findings or recommendations, and implement/document corrective and preventive actions to maintain compliance and quality standards. • Monitor site and clinic performance trends regularly, proactively identifying areas for improvement and implementing corrective strategies to drive operational efficiency and excellence. • Cultivate and maintain a professional, respectful working relationship with all affiliated physicians, ensuring alignment of clinical responsibilities and fostering site-level collaboration. • Identify and engage additional physicians when needed to support protocol-specific assessments or examinations, ensuring study timelines and requirements are consistently met. Education and Experience • Bachelor’s degree in a scientific or healthcare field • Minimum of 5 years in clinical research management or other applicable management experience Knowledge and Skills Required • Excellent written and verbal communication skills • Advanced management skills with the ability to lead a team • Ability to organize and manage multiple projects & priorities • Commitment to the vision and mission of Elite Clinical Network • Experience working with multiple IRBs, Sponsors/CROs, and vendors • Extensive knowledge and mastery of Microsoft Office, RealTime CTMS, GCP and other industry standards • Demonstrated ability to learn quickly and generate solutions to complex problems • Ability to work independently, within a multi-disciplinary team, as well as with sponsors and vendors Site Operations Expectations • On-Site Presence: Site Managers are expected to be physically present at their assigned clinic Monday through Friday during standard operating hours, for a minimum of 8 hours per day and 40 hours per week. • Time Off Protocol: If time off is needed, prior notification must be given to your Regional Site Manager. Approval should be obtained before it is taken. • Coverage Responsibility: It is the Site Manager’s responsibility to ensure that all operational duties are adequately covered during any absence. This includes coordinating with appropriate team members to maintain seamless clinic operations. Email Communication Protocol • Timely Response Requirement: All emails must be reviewed and responded to within 24 hours of receipt to ensure timely communication and operational efficiency. • Inclusion of Leadership: The Regional Site Manager (RSM) must be copied (CC’d) on all email correspondence related to site operations, clinical activities, or sponsor communications. Sponsor and CRA Communication • Site staff must inform all sponsor representatives, Clinical Research Associates (CRAs), and CRO contacts to include the Regional Site Manager on all future communications involving the site. This ensures transparency, accountability, and consistent oversight of study activities. Job Types: Full-time, Contract Benefits: • Health, Vision, and Dental insurance • Paid time off Work Location: In person, Clinton Township, Michigan

Support clinical trial contracting, budget management, study tracking, and cross-functional alignment to ensure timely and compliant trial execution. | 1+ years industry experience in pharmaceutical/biotech/CRO, knowledge of study phases, strong communication skills, and preferably a bachelor's degree. | Position Summary Elite Clinical Network is seeking a Clinical Trials Associate with a specialized focus on clinical contract activities and budget management to support our growing portfolio of clinical research studies. This role is critical in ensuring the timely execution of site agreements, amendments, and budget negotiations, enabling our trials to launch on schedule and remain financially compliant. By providing expertise in contract language, cost analysis, and site budget alignment, the Clinical Trials Associate will play a key role in maintaining strong sponsor and site relationships while safeguarding ECN’s operational efficiency and fiscal integrity. Essential Functions: • Supports contracting activities related to study start-up and maintenance. • Supports the Contract and Budget Managers prepare and maintain study documents as applicable • Organize study related meetings including but not limited to preparation of agenda/ minute taking and maintenance of risk/ issue/ decision logs • General study tracking and maintenance • Assist and support contracting data related activities including data review, query creation and resolution • Supports study reporting and tracking with applicable systems and technology • Supports study lead in cross-functional alignment of study timelines Preferred Qualifications: • 1 or more years industry experience from Pharmaceutical, Biotechnology or Contract Research Organization (CRO) • Understanding of study phases and general knowledge of how they apply to clinical development • Demonstrate ability to work independently and in a team environment • Advanced knowledge of Word, Excel, SharePoint. • (CTMS is a plus) • Strong verbal and written communication skills required. Required/Preferred Education and Licenses • Bachelor’s degree preferred • Clinical experience is preferred

Lead and manage patient recruitment marketing team, oversee recruitment campaigns across multiple channels, manage budgets and vendors, and optimize recruitment strategies with ROI focus. | Bachelor's degree in relevant field, 3+ years SEO/SEM experience, 3-5 years clinical research experience with 2+ years in patient recruitment, team management skills, and proficiency with digital marketing tools and CTMS. | Position Summary We are seeking a motivated and creative individual to join our growing Patient Recruitment Marketing (PRM) Team in the position of Manager of Patient Recruitment. In this role, you will lead the Patient Recruitment Marketing team, reporting to the Patient Recruitment Director, and be directly responsible for managing patient recruiters, patient screening volume, generating new patient leads through defined Patient Recruitment and Retention strategies, thereby increasing Elite Clinical Network’s national expansion through a variety of marketing duties and tasks. You will work with the marketing team on various patient recruitment campaigns across the United States, utilizing multiple channels. You will assist execution and direction of ECN’s internal patient recruitment marketing team with a keen emphasis on ROI and reporting. Responsibilities • Assist in supporting marketing efforts of Elite Clinical Network from a corporate and site-specific perspective, including contributing to the creation of meaningful content targeting patients. • Assist the marketing team with patient recruitment activities to optimize the visibility of clinical trial sites within the network, including patient recruitment funnels across channels (radio, print, grassroots, Google Ads, and Facebook Meta). • Provide management and oversight of patient recruiters and related vendors, including allocation of spend and ensuring quality, accuracy, and adherence to timelines. • Onboard and train new patient recruiters. • Identify recruiter or site burden, and assist in implementing effective solutions. • Escalate employee performance issues and concerns to your Director in a prompt, professional manner. • Clearly demonstrate patient recruitment performance with ROI metrics and associated reporting frequently. • Manage and organize CTMS patient and study data. • Create and implement process flows and train patient recruiters on procedures and best practices. • Drive patient recruitment strategies through outreach activities as directed by the Head of Marketing and/Director of Patient Recruitment. • Serve as point-of-contact with all patient recruiters and assist in communication with Site Managers (SM’s). • Assist in the management of patient recruitment/engagement spend in accordance with sponsor budget requirements. • Effectively, multitask and balance patient recruitment/engagement activities across a multi-site, multi-entity environment. • Follow study timelines and trends closely and assist in the execution of recruitment strategy as needed. Qualifications • Bachelor's degree in marketing, communications, life sciences, community health, public health or related field. Life sciences and higher-level degrees preferred. • Excellent communication, presentation, and interpersonal skills. • Self-motivated and a team player. • Ability to work collaboratively in a fast-paced and dynamic environment. • Minimum of 3 years of SEO or SEM experience; experience in health marketing is a plus. • Preferred 3 to 5 years' experience of Clinical Research industry experience, with at least 2 years' experience related to Patient Recruitment. • Experience managing large patient recruitment teams. • Knowledge of Google Analytics, Google Ads, Facebook (Meta)/IG marketing, other online advertising verticals and CTMS. • Proficient in current recruitment best practices and trends across the industry.