BeOne Medicines

Lead clinical development projects, develop clinical strategies, and oversee study execution in oncology therapeutics. | Requires an advanced degree in a relevant scientific discipline, 8+ years in biotech/pharma, and expertise in oncology and translational medicine. | Job Description: • Lead clinical development of at least one high impact project • Determine the most expeditious path to progress for patients • Chart a course for the next wave of multifunctional assets at BeOne • Support BeOne Medicine’s clinical and medical assets • Successful execution of clinical development programs • Collaboration with external vendors and academicians • Accountability for developing clinical program strategy • Assure activities are executed within expected scope, budget, and timelines • Establish and grow Clinical Research functions • Provide leadership and clinical oversight for assigned studies and programs • Facilitate generation of key documents (protocols, consent documents, study reports, etc.) • Partner with clinical operations for successful clinical study implementation • Train internal and external staff on therapeutic area and clinical protocol Requirements: • Advanced degree in a relevant scientific or clinical discipline (e.g. MD, PhD, or PharmD) • Minimum of 8+ years of experience and success within biotech/pharmaceutical industry and/or equivalent experience in academia • Professional knowledge and skills working in oncology therapeutics across solid tumor types is required • Proficiency in translational medicine is required • Strategic leader with demonstrated success building, managing, and developing individuals and teams • Working knowledge of applicable International Compliance guidelines and regulations is expected • Experience working in a global environment is required • Experience with the development and support of related SOP’s and policies is expected • Experience with partnerships and strategic alliances is expected • Extensive history of participation in filing activities leading to global approvals is preferred Benefits: • Medical • Dental • Vision • 401(k) • FSA/HSA • Life Insurance • Paid Time Off • Wellness

Perform and interpret QC chemistry tests, troubleshoot analytical methods, and support GMP manufacturing processes. | Bachelor's in Chemistry, Biochemistry, or related, with 4+ years in FDA-regulated biotech, and experience with chromatography and GMP regulations. | BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. General Description Perform QC Chemistry laboratory activities with a primary focus on capillary electrophoresis techniques to support GMP manufacturing, testing, and release of material, intermediates and finished biological products (monoclonal antibodies) under FDA/EU regulations, applicable International Regulations, and BeOne Medicines’ processes and procedures. Essential Functions Of The Job • Perform routine and non-routine testing using capillary electrophoresis techniques (e.g., CE-SDS, CZE, icIEF) in the QC Chemistry laboratory to ensure timely and compliant generation and reporting of in-process, release, and stability test results in support of manufacturing operations. • Review, interpret, and report analytical data in accordance with GMP regulations and internal procedures. • Lead troubleshooting efforts for analytical methods and instrumentation related to CE. • Conduct laboratory investigations, including OOS, Out of Trend, deviations, and invalid assays. • Implement corrective actions and preventive actions (CAPAs). • Participate in transfer and method validation activities, including protocol preparation, protocol execution, and report preparation. • Support routine operations, including but not limited to instrument qualification and maintenance, SOP generation and revision, test record keeping, etc. • Maintain equipment in a qualified and calibrated state, coordinating with metrology or vendors as needed. • Manage inventory of reagents and supplies for the laboratory. • Participate in internal and external GMP audits, as needed. • Train other junior level analysts and new hires on CE instrumentation, GMP practices, and data analysis. • Serving as subject matter expert in one or more areas of required testing. • Interacts with all levels of BeOne employees. • Undertake other duties as required. Education/Experience Required • Bachelor’s or above in Chemistry, Biochemistry, or Biotechnology related scientific discipline. • Minimum of 4+ years of working experience in an FDA-regulated biotechnology, pharmaceutical company are required. • Working knowledge and experience with chemistry analytical methods such as HPLC, GC, TOC, Capillary Electrophoresis (CGE-Reduced, CGE-Non-Reduced, and Capillary Zone Electrophoresis), etc. • Familiar with Waters Empower Chromatography Data System. • Familiar with instrument and equipment validation. Impressive, demonstrable track record and skills/experience gained within a similar position(s), at a similar level. Working knowledge with USP/EP and cGMP/EU GMP regulations. • Impressive, demonstrable track record and skills/experience gained within a similar position(s), at a similar level. • Credible and confident communicator (written and verbal) at all levels. • Strong analytical and problem-solving ability. • Hands-on approach, with a ‘can do’ attitude. • Ability to prioritize, demonstrating good time management skills. • Excellent attention to detail, with the ability to work accurately in a busy and demanding environment. • Self-motivated, with the ability to work proactively using own initiative. • Committed to learning and development. Computer Skills • Strong PC literacy required; MS Office skills (Outlook, Word, Excel, PowerPoint). Travel • Must be willing to travel approximately 10%. • Ability to work on a computer for extended periods of time. Global Competencies When we exhibit our values of Patients First, Collaborative Spirit, Bold Ingenuity and Driving Excellence, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. • Collaborative Spirit Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively • Bold Ingenuity Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change • Driving Excellence Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. • Fosters Teamwork • Provides and Solicits Honest and Actionable Feedback • Self-Awareness • Acts Inclusively • Demonstrates Initiative • Entrepreneurial Mindset • Continuous Learning • Embraces Change • Results-Oriented • Analytical Thinking/Data Analysis • Financial Excellence • Communicates with Clarity Salary Range: $90,900.00 - $125,900.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com.

Develop and oversee global infrastructure and cloud strategies, ensuring high availability, security, and modernization across multiple regions. | Over 14 years of experience in IT infrastructure and cloud computing, with proven expertise in AWS and Azure, strong leadership skills, and relevant certifications. | Job Description: • Develop and execute the global infrastructure and cloud strategy aligned with business objectives • Oversee architecture, engineering, and operations for network, compute, storage, and cloud platforms • Lead compliance and optimization initiatives across AWS and Azure environments • Ensure high availability, disaster recovery, and performance monitoring for all infrastructure services across all BeOne operating regions • Drive automation and modernization initiatives using Infrastructure as Code (IaC) tools such as Terraform • Establish and maintain data center standards, including physical and virtual infrastructure best practices • Oversee system administration for enterprise servers, operating systems, and core infrastructure services • Implement proactive monitoring and observability frameworks to ensure reliability and rapid incident response • Manage vendor relationships and negotiate contracts for infrastructure and cloud services • Collaborate with cybersecurity, application development, and business teams to ensure seamless integration • Establish governance frameworks and performance metrics for infrastructure and cloud services • Mentor and develop a global team of engineers and architects • Partner with cybersecurity team to ensure the highest standards of security are applied and maintained to the technology stack • Partner with BeOne technology leaders and stakeholders to ensure technology stack supports business goals Requirements: • Minimum 14+ years of experience in IT infrastructure and cloud computing • Proven expertise in AWS and Azure cloud platform management and architecture • Alicloud, Tencent experience is a plus • Strong background in network engineering, enterprise architecture, Terraform, system administration, and monitoring solutions • Demonstrated experience managing global infrastructure operations and large-scale cloud migrations • Excellent leadership, communication, and stakeholder management skills • Bachelor’s degree in Computer Science, Information Technology, or related field (Master’s preferred) • Experience in biotech or pharmaceutical industry, with understanding of regulatory and compliance requirements • Familiarity with GxP, HIPAA, and other industry standards • Advanced certifications in cloud technologies (AWS Certified Solutions Architect, Azure Solutions Architect Expert) Benefits: • Medical • Dental • Vision • 401(k) • FSA/HSA • Life Insurance • Paid Time Off • Wellness