Alnylam Pharmaceuticals

Developing and executing comprehensive marketing strategies for biopharmaceutical products, leading cross-functional teams, and managing stakeholder relationships. | Extensive experience (~15 years) in biopharma marketing, managing large teams, successful product launches, and deep understanding of healthcare regulations and reimbursement landscape. | Overview The VP, Head of US TTR Marketing, is a highly visible, mission-critical role that will report to the SVP, US Head of Business and will be a core member of the US Leadership Team. This person will be pivotal in defining the goals, strategies, tactics, and metrics necessary for maximizing the potential of Alnylam’s US TTR franchise. The VP will lead a team of 20-30 marketers and thought leader liaisons (TLLs), fostering a culture of customer-centricity, thoughtful risk-taking, and cross-functional partnership. This person’s leadership will be instrumental in maximizing Alnylam’s competitiveness, navigating the complexities of the biopharmaceutical landscape, building and cultivating strong relationships with key stakeholders, and enhancing patient access to our life-preserving therapies. A key element of this person’s success will be building a culture of deep collaboration across the breadth of Alnylam’s functions including Sales, Account Management, Medical Affairs, Market Access, Patient Services, Legal, and Compliance. This is a virtual position but will require regular travel to Alnylam’s headquarters in Cambridge, MA. Key Responsibilities • Strategic Planning: Develop and implement comprehensive marketing strategies for driving awareness and diagnosis of TTR amyloidosis, and for maintaining high preference/market share of Amvuttra and Onpattro among HCPs and patients. • Team Leadership: Lead, mentor, and develop a multidisciplinary marketing team, fostering a culture of customer-centricity, thoughtful risk-taking, and cross-functional partnership. Ensure alignment of goals, strategies, and tactics across the marketing team as well as the broader cross-functional team spanning Medical Affairs, Sales, Account Management, Market Access, Patient Services, Regulatory, and Legal. • Brand Management: Oversee the development and execution of brand strategies, ensuring consistent messaging across all channels and touchpoints. Drive brand awareness, engagement, and loyalty among target audiences. • Market Insights: Leverage market research and data analytics to gain insights into customer behaviors and market trends. Inform strategic decisions and optimize marketing campaigns to meet market needs effectively. • Stakeholder Engagement: Cultivate strong relationships with key opinion leaders, patient advocacy groups, and professional organizations. Develop and support programs that enhance disease awareness and education. • Regulatory Compliance: Ensure all marketing activities comply with regulatory guidelines and ethical standards. Work closely with legal and regulatory teams to navigate the approval process for marketing materials and campaigns. • Performance Metrics: Establish and monitor key performance indicators to measure the effectiveness of marketing strategies. Adjust plans as necessary to achieve business objectives. Qualifications • Bachelor’s degree required, MBA or advanced degree in a related field preferred. • ~15 years of US/global biopharma marketing and business experience, with experience managing sizable teams • Proven track record of developing and executing successful marketing campaigns and strategies in competitive markets for pharmaceutical products. Experience at large biopharma company preferred. New product launch experience is a must. • Extensive experience with HCP and consumer marketing, as well as engagement with, and cultivation of, thought leaders. • Experience in cardiology preferred. • Deep understanding of the US healthcare system, reimbursement landscape, and regulatory environment. • Strategic thinker with the ability to analyze complex data and market insights to drive decision-making. • Strong leadership, communication, and collaboration skills. • Excellent communication, negotiation, and interpersonal skills. Strong executive presence • Demonstrated ability to lead and inspire a team towards achieving common goals. • Demonstrated ability to foster and drive cross-functional collaboration. • Possesses high integrity and exceptional work ethic. • Willingness to travel as needed. #LI-Remote #LI-ST1 U.S. Pay Range $323,000.00 - $437,000.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Developing and executing marketing strategies for biopharma products, leading a large team, and managing stakeholder relationships. | Extensive experience in biopharma marketing, team management, product launch, and familiarity with healthcare regulations. | Overview The VP, Head of US TTR Marketing, is a highly visible, mission-critical role that will report to the SVP, US Head of Business and will be a core member of the US Leadership Team. This person will be pivotal in defining the goals, strategies, tactics, and metrics necessary for maximizing the potential of Alnylam’s US TTR franchise. The VP will lead a team of 20-30 marketers and thought leader liaisons (TLLs), fostering a culture of customer-centricity, thoughtful risk-taking, and cross-functional partnership. This person’s leadership will be instrumental in maximizing Alnylam’s competitiveness, navigating the complexities of the biopharmaceutical landscape, building and cultivating strong relationships with key stakeholders, and enhancing patient access to our life-preserving therapies. A key element of this person’s success will be building a culture of deep collaboration across the breadth of Alnylam’s functions including Sales, Account Management, Medical Affairs, Market Access, Patient Services, Legal, and Compliance. This is a virtual position but will require regular travel to Alnylam’s headquarters in Cambridge, MA. Key Responsibilities Strategic Planning: Develop and implement comprehensive marketing strategies for driving awareness and diagnosis of TTR amyloidosis, and for maintaining high preference/market share of Amvuttra and Onpattro among HCPs and patients. Team Leadership: Lead, mentor, and develop a multidisciplinary marketing team, fostering a culture of customer-centricity, thoughtful risk-taking, and cross-functional partnership. Ensure alignment of goals, strategies, and tactics across the marketing team as well as the broader cross-functional team spanning Medical Affairs, Sales, Account Management, Market Access, Patient Services, Regulatory, and Legal. Brand Management: Oversee the development and execution of brand strategies, ensuring consistent messaging across all channels and touchpoints. Drive brand awareness, engagement, and loyalty among target audiences. Market Insights: Leverage market research and data analytics to gain insights into customer behaviors and market trends. Inform strategic decisions and optimize marketing campaigns to meet market needs effectively. Stakeholder Engagement: Cultivate strong relationships with key opinion leaders, patient advocacy groups, and professional organizations. Develop and support programs that enhance disease awareness and education. Regulatory Compliance: Ensure all marketing activities comply with regulatory guidelines and ethical standards. Work closely with legal and regulatory teams to navigate the approval process for marketing materials and campaigns. Performance Metrics: Establish and monitor key performance indicators to measure the effectiveness of marketing strategies. Adjust plans as necessary to achieve business objectives. Qualifications Bachelor’s degree required, MBA or advanced degree in a related field preferred. ~15 years of US/global biopharma marketing and business experience, with experience managing sizable teams Proven track record of developing and executing successful marketing campaigns and strategies in competitive markets for pharmaceutical products. Experience at large biopharma company preferred. New product launch experience is a must. Extensive experience with HCP and consumer marketing, as well as engagement with, and cultivation of, thought leaders. Experience in cardiology preferred. Deep understanding of the US healthcare system, reimbursement landscape, and regulatory environment. Strategic thinker with the ability to analyze complex data and market insights to drive decision-making. Strong leadership, communication, and collaboration skills. Excellent communication, negotiation, and interpersonal skills. Strong executive presence Demonstrated ability to lead and inspire a team towards achieving common goals. Demonstrated ability to foster and drive cross-functional collaboration. Possesses high integrity and exceptional work ethic. Willingness to travel as needed. #LI-Remote #LI-ST1 U.S. Pay Range $323,000.00 - $437,000.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Facilitating strategic planning, prioritization, and execution of high-impact projects within Clinical Development, and serving as a trusted partner to senior leaders. | Over 10 years of experience, preferably with biotech/pharma R&D, strong project management skills, and ability to influence senior stakeholders. | Overview The Director, Development Strategy & Operations role will be focused on delivering the near- and long-term objectives of the R&D Leadership Team as Alnylam delivers the next wave of transformational medicines. Reporting to the Executive Director, Development Strategy, Operations, & Portfolio, this role will have broad responsibility for strategic planning and operational delivery within Clinical Development. This individual will drive high-priority projects for the Development organization, facilitate effective prioritization and decision-making, and serve as a thought-partner and executor for senior leaders in the Clinical Development organization (e.g., Pipeline Delivery & Clinical Operations, Clinical Research, Quantitative Sciences). As a partner to senior leaders Clinical Development, this role requires a highly resourceful person with strong emotional intelligence, self-motivation, proven cross-functional collaboration abilities, and the ability to manage ambiguity and thrive in a fast-paced environment. Key Responsibilities Enable a strong connection between the week-to-week operations of the Development and the long-term enterprise strategic roadmap Support R&D senior leaders in identifying, scoping, organizing, leading execution, and monitoring progress on priority initiatives (e.g., accelerating cycle times and speed to market) Contribute to above-asset and portfolio-wide analyses and initiatives such as disease area strategies, portfolio scenario planning and portfolio prioritization, strategic resource planning and management, etc. Drive corporate planning deliverables (annual goal setting, annual investment planning, long-range planning) via thought-partnership with senior leaders, delivering analyses, and running a tight process in coordination with other expertise areas (e.g., Finance) Facilitate effective decision-making and follow-through on actions, e.g., for pipeline Governance meetings and priority initiatives steering committees Be a trusted thought-partner and problem-solving partner with senior R&D Leaders and the Executive Director, R&D Strategy, Operations, & Portfolio Prepare analyses, gather and structure data, structure ambiguous problems, and distill into executive-level communications Qualifications Bachelor’s degree in scientific or business discipline; MBA or PhD preferred 10+ years of experience, 7 of which in the biotechnology, pharmaceutical, and/or management consulting or professional services, with experience in Clinical Development and R&D Experience working on high-visibility projects with frequent engagement with senior stakeholders Excellent problem solving and execution skills Ability to manage ambiguity and multitask Strong project management and matrix working skills Ability to build trust and effective working relationships with colleagues across functional groups and levels of seniority (including senior executives) Strong written and oral communication skills Ability to influence without authority Energized by working in a highly entrepreneurial biotech environment Intellectual curiosity, adaptability, and desire to learn and continually build skills U.S. Pay Range $236,100.00 - $319,500.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Leading strategic engagement and contracting with target key accounts to drive growth, revenue, and joint value creation for Alnylam. | Minimum 7 years of B2B selling experience in life sciences, with account management experience in health systems or hospitals, and strong scientific communication skills. | Overview The Strategic Account Lead (SAL) role leads strategic engagement and contracting with target key accounts in order to drive growth, revenue, and joint value creation for Alnylam and the customer by enabling and optimizing access to Alnylam products and driving innovation for patients and health care providers. Key Responsibilities The Strategic Account Lead (SAL) will provide innovative, influential account engagement to shape and deliver the strategy for Alnylam Strategic Accounts in order to achieve access, create value and deliver profitable growth for Alnylam. Lead the development and execution of the comprehensive account strategy for target accounts to bring the best of Alnylam to the customer and to maximize profitability, revenue growth and market share for Alnylam Analyze and synthesize information from multiple sources to identify and prioritize business opportunities across the account by applying relevant frameworks and analytical methods Work with the Alnylam Leadership Team to co-develop and agree on strategies, programs objectives and KPIs for target regional accounts aligned with organizational and brand priorities and the wider business strategy Support the account team with the prioritization of solutions, programs and specific pull-through tactics to ensure sustainable growth and mutual value creation Anticipate likely market and customer developments, identify third party influence factors and shape the account strategy accordingly Partner with target healthcare systems and organized customers to foster innovation in care through the adoption of Alnylam’s products Engage senior level stakeholders to influence policies, decisions and perceptions to enable patients to effectively navigate the treatment journey and ensure appropriate use of Alnylam products Facilitate the introduction of new products and indications with institutional stakeholders by ensuring adequate budget allocation at the strategic account level Leverage a range of strategies and tactics to maximize the level and quality of access for Alnylam products Identify programs to partner with the Organized Customer to enhance the system of care and clinical decision making Provide insights, education and information about scientific, clinical and technological innovation Facilitate strategic partnership with account stakeholders to create mutual value for Alnylam and customers and deliver strategic goals Identify and maintain strong relationships with senior business stakeholders (Chief, VP, Director) in target accounts to support access for Alnylam’s products across the company portfolio Strengthen the perception of Alnylam as a strategic partner by sharing insights and information to support patient identification and improving the delivery of care by establishing treatment pathways and protocols Provide clear direction to other field teams to identify and prioritize stakeholders within their target accounts Negotiate, review and agree contracts, incorporating solutions to strengthen partnerships with strategic account stakeholders Collaborate with other functional and business leaders to ensure adequate Voice of the Customer to inform strategic planning across all stakeholders and channels Support the delivery of account goals for National accounts, working closely with the Strategic Accounts Team Support the execution and pull through of contracting and initiatives with national organized customers to ensure value maximization Measure, report and communicate value delivered for national organized customers in order to strengthen customer partnership Share insights gathered through customer engagement Qualifications Bachelor’s degree, emphasis in Accounting, Marketing, Business Administration or equivalent work experience in business management, ideally complemented by an MBA Minimum 7 years of experience in B2B selling in a life sciences environment Previous account management experience with health systems and/or hospitals/ IDNs High level of confidence and capability to understand and communicate complex scientific concepts to a range of stakeholders, plus executive presence and communication skills to engage with a C-Suite audience Expertise and understanding of dynamic market access value models such as value-based propositions and budget impact and cost effectiveness models, etc Strong interpersonal skills including written and oral communication skills, ability to synthesize data, interpret and translate into compelling and clear commercial strategies and plans Demonstrated ability to successfully mobilize a cross-functional team, including interpersonal skills to foster collaboration and succeed in a highly matrixed environment by leading without direct authority Understanding of the IDN environment, including coverage and reimbursement, pricing and contracting, formulary management and health technology assessment Strong analytical skills and ability to think critically, challenge conclusions and underlying assumptions Ability to synthesize multi-source information (qualitative and quantitative) to develop strategic plans Knowledge of value based healthcare and outcome based models Executive presence and the ability to interact and negotiate with C-suite customers Highly proficient in Microsoft; Excel, Word, and PowerPoint Additional Preferred Experience Master’s degree: Master of Business Administration (MBA) preferred Active membership of relevant pharmaceutical associations would be beneficial #LI-ST1 #LI-Remote U.S. Pay Range $204,000.00 - $276,000.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Develop and execute program-level operational strategies for clinical development, ensuring cross-functional alignment, risk mitigation, and successful trial delivery. | Extensive experience in clinical research operations, leadership of outsourced teams, and strategic planning within biopharmaceutical or CRO environments. | The Director is accountable for the operational execution of the Clinical Development Plan (CDP). As a disease area thought partner, the Director is responsible for the development of the program-level operational strategy and ensuring cross-functional alignment, identifying, and resolving program-level risks that may impact timelines or budgets. The Director is also responsible for leading a team of Associate Directors, Sr. Managers, and Managers within the Global Trial Strategy & Operations (GTSO) Organization. The position is responsible for staff development, project assignments, workload distribution, resourcing, and prioritization. The Director directly influences departmental planning and strategy, resource allocation and management, functional communication activities, alignment of goals with organizational and trial objectives. This position ensures common operational issues/challenges are identified proactively across trials and programs and are addressed through operational risk mitigation, including proposals for alternative solutions. Summary of Key Responsibilities: Responsible for the development of the program-level operational strategy and ensuring alignment across functions, e.g., E2E connectivity across functions, share lessons learned for program-level consistency, and monitor KPIs to track program-level success). Accountable for the delivery of the operational strategy in alignment with the Clinical Development Plan, ensuring alignment with the business goals and trial delivery objectives (including resourcing, budget, and change control, partnering with CDST sub-teams, timeline creation). Accountable for representing assigned programs at cross-functional and executive governance forums, presenting operational strategy, risks, and trade-offs, and driving timely, data-informed decisions to enable successful program execution. Attend CDST and function as a strategic partner with program management for the execution across all trials in the program. Attend Leadership Team meetings as required/ requested to provide study updates or as a back-up for senior GTSO leaders. Lead operational scenario planning and mitigate program level risk that may Impact timelines/ budget, ensure appropriate quality oversight, and appropriately escalate Issues to CDST, Quality and functional leadership. Ability to effectively communicate the operational strategy and defend the operational plan and costs associated to CDST, leadership and at governance meetings as appropriate. Lead and ensure inspection readiness for the program Provide leadership during Health Authority inspections and on the identification of risks and mitigation plans at the program level for key issues. Provide operational leadership and support to the Associate Directors Build a knowledgeable and skilled team with competencies and capabilities to successfully set up and deliver clinical trials Oversee resource allocation Promote strong collaboration across cross-functional teams Setting objectives in alignment with company, program, and departmental objectives. Ensure Staff training on procedures and systems associated with their roles Develop a team that consistently achieves strong results through nurturing individual growth, effectively managing performance, and providing guidance Effectively discusses and presents study data across the Company and with development partners; collaborates with clinical development and scientists, medical writers, and investigators to write, present and/or publish data. Participates in, reviews, and provides direction on CRO and vendor outsourcing strategy, and key performance indicators (KPIs) ensuring vendor/ CRO partners consistently deliver high quality data to support regulatory requirements. High Engagement with Peer group to ensure lessons learned and best practice sharing across TAs Key Skills: Must have experience leading/managing externally outsourced, cross-functional teams. Experience in and knowledge of the pharmaceutical development process Clinical Research operational knowledge and deep experience across multiple phases of studies (1-4). Must have the ability to manage all aspects of execution of a clinical trial Excellent decision-making, analytical and strong financial management skills are essential to this position Strong project planning/management, communication and presentation skills Must possess excellent leadership skills and proven ability to foster team productivity and cohesiveness Experience leading without authority and in multifunctional matrixed and global environments Operate and execute with limited supervision Willingness and proven ability to work flexibly, stepping outside of immediate role responsibilities and wearing multiple hats where needed. Confident and has the professional competence to win respect and gain credibility at all levels within and outside the Company, and capable of successfully representing the Company externally. Strategic Thinking: General knowledge of all major aspects of drug discovery and development along with effective departmental leadership to be an effective problem solver for complex problems. Qualifications: BSc/ BA degree required - Advanced degree preferred. Minimum 10+ years previous experience gained with a CRO and/or biopharmaceutical company Minimum 5+ years prior line management experience or 5 years matrixed leadership experience required Ability to travel 10-15%. #LI-AL1 U.S. Pay Range $196,600.00 - $266,000.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Support and evaluate biotech business development initiatives through financial analysis, modeling, and strategic insights, leading a team and influencing senior stakeholders. | Minimum 10+ years in biotech or pharma finance, strong financial modeling skills, experience supporting R&D or business development functions, and ability to communicate complex financial data effectively. | Overview: Alnylam Pharmaceuticals is seeking a Director of Business Development FP&A to serve as a senior, finance-focused partner within the Business Development Finance organization. This role is intended for a highly analytical, enterprise-minded finance professional who leads through rigorous analysis and sound financial judgment, supports external growth and enterprise initiatives, and provides disciplined decision support across a large, global biotech organization. The role includes oversight and development of one direct report and is best suited for candidates seeking continued growth within Finance. Key Responsibilities Business Development Support & Evaluations: Lead and execute financial evaluations in support of the Business Development organization, including valuation modeling, scenario and sensitivity analyses, and comparable transaction benchmarking Deliver hands-on financial analyses for potential and existing alliances and partnerships to support strategic reviews, business cases, and long-range planning Oversee, review, and coach one direct report, ensuring high-quality financial models, sound assumptions, and consistent analytical standards Serve on deal teams, providing valuation, diligence, and analytical support throughout the transaction lifecycle while maintaining independent financial judgment Review term sheets and contracts, advising on financial aspects and key provisions, and coordinate input from Accounting, Tax, Treasury, and other finance functions to ensure a comprehensive and consistent financial perspective Strategic Projects supporting the Enterprise: Partner with senior leaders across R&D, Technical Operations, and Commercial to translate complex business questions into financial frameworks and decision-ready analyses Lead and execute finance-led strategic analyses for the Executive Leadership Team (ELT), delivering clear, data-driven insights to support enterprise strategic and operational decisions Synthesize analyses into actionable, finance-grounded recommendations that inform strategic planning, capital allocation, and operational improvement initiatives Team Enablement & Modeling Excellence: Directly manage and develop one finance professional, providing coaching, technical guidance, and performance feedback Contribute to the development and continuous improvement of tools, templates, and best practices that elevate analytical rigor and consistency across the Finance organization Qualifications Basic Requirements: Bachelor’s Degree in Finance or other degrees with quantitative focus (e.g. Statistics, Economics, Mathematics) required. MBA, CFA, or equivalent strongly preferred. A minimum of 10+ years of progressive experience in Finance within biotech, pharma, or life sciences Strong business acumen with experience supporting R&D, portfolio, or business development functions Strong understanding of financial models, valuations, and business proposals Ability to manage multiple priorities and deliver high-quality work under tight timelines Demonstrated ability to influence and communicate effectively with senior stakeholders in a matrixed environment Demonstrated ability to translate complex financial information and assumptions into effective presentations Important Knowledge & Skills: Advanced financial modeling and valuation skills — ability to build and interpret discounted cash flow (DCF), NPV, IRR, and scenario-based models for BD and strategic decisions Strong intellectual curiosity and initiative – proactively identifying opportunities for optimization or insight generation Strong collaboration skills, with an ability to inspire and motivate teams Excellent analytical, strategic planning, and problem-solving skills Thrives in a fast-paced, matrixed environment where priorities shift and collaboration is key Attention to detail and high standards of analytical accuracy under tight timelines Ability to influence and build relationships at all levels of the organization #LI-MH1 #LI-Hybrid U.S. Pay Range $195,500.00 - $264,500.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Support and evaluate business development initiatives through financial analysis, modeling, and strategic insights, while managing a team and influencing senior stakeholders. | Extensive experience in finance, biotech, or pharma, with strong modeling skills, leadership abilities, and the capacity to support enterprise-level strategic decisions. | Overview Alnylam Pharmaceuticals is seeking a Director of Business Development FP&A to serve as a senior, finance-focused partner within the Business Development Finance organization. This role is intended for a highly analytical, enterprise-minded finance professional who leads through rigorous analysis and sound financial judgment, supports external growth and enterprise initiatives, and provides disciplined decision support across a large, global biotech organization. The role includes oversight and development of one direct report and is best suited for candidates seeking continued growth within Finance. Key Responsibilities Business Development Support & Evaluations: • Lead and execute financial evaluations in support of the Business Development organization, including valuation modeling, scenario and sensitivity analyses, and comparable transaction benchmarking • Deliver hands-on financial analyses for potential and existing alliances and partnerships to support strategic reviews, business cases, and long-range planning • Oversee, review, and coach one direct report, ensuring high-quality financial models, sound assumptions, and consistent analytical standards • Serve on deal teams, providing valuation, diligence, and analytical support throughout the transaction lifecycle while maintaining independent financial judgment • Review term sheets and contracts, advising on financial aspects and key provisions, and coordinate input from Accounting, Tax, Treasury, and other finance functions to ensure a comprehensive and consistent financial perspective Strategic Projects Supporting The Enterprise • Partner with senior leaders across R&D, Technical Operations, and Commercial to translate complex business questions into financial frameworks and decision-ready analyses • Lead and execute finance-led strategic analyses for the Executive Leadership Team (ELT), delivering clear, data-driven insights to support enterprise strategic and operational decisions • Synthesize analyses into actionable, finance-grounded recommendations that inform strategic planning, capital allocation, and operational improvement initiatives Team Enablement & Modeling Excellence • Directly manage and develop one finance professional, providing coaching, technical guidance, and performance feedback • Contribute to the development and continuous improvement of tools, templates, and best practices that elevate analytical rigor and consistency across the Finance organization Qualifications Basic Requirements: • Bachelor’s Degree in Finance or other degrees with quantitative focus (e.g. Statistics, Economics, Mathematics) required. MBA, CFA, or equivalent strongly preferred. • A minimum of 10+ years of progressive experience in Finance within biotech, pharma, or life sciences • Strong business acumen with experience supporting R&D, portfolio, or business development functions • Strong understanding of financial models, valuations, and business proposals • Ability to manage multiple priorities and deliver high-quality work under tight timelines • Demonstrated ability to influence and communicate effectively with senior stakeholders in a matrixed environment • Demonstrated ability to translate complex financial information and assumptions into effective presentations Important Knowledge & Skills • Advanced financial modeling and valuation skills — ability to build and interpret discounted cash flow (DCF), NPV, IRR, and scenario-based models for BD and strategic decisions • Strong intellectual curiosity and initiative – proactively identifying opportunities for optimization or insight generation • Strong collaboration skills, with an ability to inspire and motivate teams • Excellent analytical, strategic planning, and problem-solving skills • Thrives in a fast-paced, matrixed environment where priorities shift and collaboration is key • Attention to detail and high standards of analytical accuracy under tight timelines • Ability to influence and build relationships at all levels of the organization U.S. Pay Range $195,500.00 - $264,500.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Manage and optimize relationships with key healthcare accounts to drive revenue and strategic partnerships. | Minimum 10 years in life sciences, 5 years in account management with health systems or payors, and strong communication skills. | Overview Reporting to the Site of Care National Director, the Strategic Account Lead, Site of Care will optimize access to Alnylam products through strategic engagement and contracting with key Alternate Site of Care accounts. This position requires a professional who can leverage their technical expertise and experience to drive growth, revenue and joint value creation for Alnylam and the customer through innovation for patients and health care providers. A key component of this role is the ability to establish and deepen customer relationships through quality interactions at targeted strategic accounts. As such, extensive knowledge of ‘buy and bill’ products and prior experience with high-touch, specialty products is essential. The successful candidate must be passionate about science and deeply motivated by the quest of delivering value to patients with the long-term success of the company in mind. They will work collaboratively with both internal and external stakeholders to execute strategic imperatives. Key Responsibilities Execute the comprehensive account strategy for key accounts to bring the best of Alnylam to the customer and to maximize profitability, revenue growth and market share for Alnylam Analyze and synthesize information from multiple sources to identify and prioritize business opportunities and potential risk across the accounts by applying relevant frameworks and analytical methods Work with the National Strategic Account Director and provide insights that inform strategies, program objectives and KPIs for target accounts that are aligned with organizational and customer priorities Anticipate and communicate likely or transpiring market and customer developments, identify third party influence factors and shape the account engagement strategy accordingly Create and foster strong relationships and perception of Alnylam as a strategic partner with senior business stakeholders (C- and D-Suite) in target accounts, including PE-backed groups, to create mutual value, support access and deliver on strategic goals for Alnylam’s products across the company portfolio Ensure consistent, best-in-class site of care strategic account management practices across all customer engagements Negotiate, manage and pull-through agreements that incorporate solutions to strengthen partnerships between Alnylam and strategic accounts Collaborate with Commercial Leadership (Sales, Marketing, market Access, Distribution and Operations) colleagues to ensure adequate Voice of the Customer in addition to own insights to influence strategic planning across stakeholders that encourages innovation and improves service delivery Provide clear engagement direction to other field teams as they work with strategic accounts Manage the ongoing contractual agreements and relationships with strategic accounts to strengthen partnerships and unlock new business opportunities Oversee the execution of quarterly business reviews, strategic planning sessions, and long-term roadmap development with key accounts Qualifications Bachelor’s degree required, emphasis in business management; Master’s degree preferred Minimum 10 years’ of experience in the life sciences environment Minimum 5 years’ previous account management experience with health systems or alternate sites of care C- and D-Suite or payors High level of confidence, exceptional written and oral communication skills and executive presence required to engage with a C-Suite audience Strong knowledge of the US payer landscape, value-based care and outcome-based models Demonstrated ability to successfully mobilize cross-functional partners, including interpersonal skills to foster collaboration and succeed by leading without direct authority Deep understanding of both medical benefit and pharmacy benefit Strong analytical skills, able to synthesize multi-source information for strategic planning and ability to think critically, challenge conclusions and underlying assumptions Self-starter who is enthusiastic about rare disease and Alnylam’s core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people Highly proficient in Microsoft Office Suite Ability to travel up to 75% Should live near a mid-sized to major airport #LI-ST1 U.S. Pay Range $204,000.00 - $276,000.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Lead and coordinate regulatory project management activities across global R&D product lifecycle, ensuring alignment, tracking submissions, facilitating meetings, and driving execution of submission strategies. | At least 6 years in regulatory affairs or project management in pharma/biotech, proficiency in project management tools, experience with global regulatory submissions, strong communication and organizational skills. | Lead regulatory-focused project management activities across the R&D product lifecycle, including global expansion. Develop and continuously optimize detailed regulatory project plans and timelines in close collaboration with the Global Regulatory Lead, Regulatory Operations, and sub-team leads. Identify and manage project interdependencies to ensure alignment across functions and understand critical path activities. Maintain real-time filing timelines and track key submissions/deliverables from investigational and marketing applications to registration. Interface with filing sub-teams to ensure mutual understanding and agreement on submission timelines and deliverables. Plan and facilitate cross-functional meetings/workshops (e.g., filing kick-off) to drive execution of submission strategies. Facilitate and co-lead critical filing team and sub-team meetings, ensuring follow-through on project deliverables and action items across the relevant expertise areas (e.g., nonclinical, CMC, clinical, regulatory functions). Ensure development of document reviewer/approver matrices and coordinate review cycles and roundtables aligned with submission timelines. Maintain comprehensive project dashboard(s) to communicate progress, risks, and key updates to teams and senior management. Proactively identify and escalate risks related to resources, timing, and deliverables as appropriate. Coordinate lessons learned sessions and facilitate implementation of feedback for process improvement Contribute to the development and refinement of best practices and standardized processes for key regulatory submissions. Bachelor's degree in life sciences, pharmacy, or related field preferred with at least 6 years' experience in regulatory affairs or project management within the pharmaceutical or biotech industry Demonstrated project management skills with strong ability to prioritize multiple projects. Formal project management training is a plus. Proficiency in project management tools (e.g., Smartsheet, MS Project) and content management systems. Experience with timeline visual tools (OnePager, Think-Cell, Office Timeline, or similar) is a plus. Experience managing global regulatory submissions for initial investigational and/or marketing applications, including response to health authority questions. Understanding of regulatory processes, requirements and experience in interpretation of Health Authority guidelines. Ability to work both independently and collaboratively within a matrixed, cross-functional environment, leveraging strong interpersonal skills to build effective partnerships across departments and levels. Excellent written and verbal communication skills, including negotiation skills. Excellent organizational and meeting management/facilitation skills. Ability to problem solve, identify bottlenecks, and escalate issues appropriately in a timely fashion. Detail-oriented with a strong sense of accountability and urgency.

Lead global clinical investigator site quality oversight by monitoring quality indicators, managing risks, ensuring compliance, supporting audits and inspections, and driving process improvements across clinical trial sites. | 6-8+ years in clinical research or quality assurance with strong knowledge of GCP regulations, quality metrics, auditing, risk management, and experience collaborating across clinical operations and quality teams. | Overview The Clinical Site Quality Oversight Lead supports the execution of quality oversight activities designed to monitor and drive improvements in clinical investigator site quality performance across programs. This position works closely with colleagues responsible for study management; Clinical Operations; Data Sciences Statistics and Epidemiology (DSSE); Clinical Research; etc. Collectively referred to as the Clinical Development Organization (CDO). The Sr. Manager, Clinical Quality Site Oversight Lead will partner and support the Alnylam CDO to ensure quality and compliance is established and maintained across clinical trial sites globally. This role will also work in close collaboration with with program/study GCP Program Leads, the R&D Quality Process Improvement team, as well as the Quality Analytics and Insights team. This role is laser focused on cross-program, global, investigator site quality and compliance. Key Responsibilities • Develop robust investigator site quality oversight, including establishment of site Key Quality Indicators (KQIs), to enable global, high-quality clinical trial execution. • Monitor risk signal detection, signal management, action planning, and action verification with the Risk Based Quality Management Team for site-level risks across clinical programs. • Monitor investigator site performance KQIs across clinical programs and studies (e.g., global and regional trends) and ensure timely escalation and action of identified issues and trends. • Monitor Investigator Site File (ISF) KQIs, ensuring compliance and readiness. Partner with TMF team to drive corrective/preventive actions at the process level to ensure inspection readiness at all times. • Utilizing site performance KQIs, Risk Signals, TMF KQIs: • Proactively identify site-specific (cross-program) quality issues or trends, ensure timely escalation, and effectively resolve emerging risks, in collaboration with GCP Program Leads, who manage study-specific compliance issues and risks. • In collaboration with the GCP QA Leads, identifying critical aspects and helping to develop the integrated Data Quality Plans (iDQP). • Support Investigator Meeting material, SIV materials, CRA training materials, as requested, and provde training or support to investigator sites in addressing queries pertaining to Quality. • Partner with Quality Analytics and Insights to develop Alnylam-facing dashboards via data integration or data shuttling from clinical trial systems to support the quality oversight of items including but not limited to major and minor protocol deviations, open/aging monitoring issues, detections delays, and data entry timeliness. • Support site-facing template review and development and help facilitate associated process improvement initiatives to ensure robust quality practices are implemented globally. • Evaluate and risk assess regulatory intelligence communications to ensure implementation of local and regional GCP requirements (or equivalent) at a site level and from a process (cross-program) perspective in emerging markets/regions. • Support Investigator site audits, as requested, and trend on observations and risks for ongoing or upcoming audits. • Support site inspection preparation and management activities, as appropriate. For example, helping to identify key risks or data points and make recommendations on sites of interest. • Define and guide global strategy and governance for investigator site systems across studies. Oversee these site systems in alignment with ICH GCP E6(R3) requirements. Qualifications • Educated in life science (technology, biological science, pharmacy or other health related discipline preferred) or equivalent work experience including clinical research, regulatory or quality. • Minimum of 6-8 years of relevant experience • Experience in quality assurance, auditing, clinical research, monitoring, data management, pharmacy, laboratory, or other relevant area, including applicable GCP auditing. • Understanding of GCP regulations and guidance for FDA, MHRA, PMDA, and International agencies including ICH guidelines. • Experience with quality metrics, management of quality events (i.e. serious breach), assessment of GCP compliance, and the application of risk-based thinking. The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Develop and execute territory and account plans targeting healthcare providers to increase brand awareness and product adoption, manage relationships with physicians and internal stakeholders, and utilize resources to drive sales results. | Requires a 4-year degree, 1-3+ years biotech or specialty pharma sales experience, strong interpersonal and communication skills, basic data analysis ability, willingness to travel extensively, and valid driver's license. | Identify and/or target healthcare providers and accounts managing and treating patients with TTR amyloidosis to develop plans to increase brand awareness and product adoption. Continuously assesses sales opportunities and challenges within territory and accounts to maintain and grow their business. Effectively prioritizes and manages time, activities, and resources to optimize access to and development of accounts with the most sales potential. Builds and maintains relationships with physicians by maximizing their time through pre-call planning, leveraging insights to tailor a call plan, and conducting post-call analysis to continually refine and enhance their approach. Proactively builds effective working relationships with internal/external stakeholders; can drive agreement/decisions from multiple stakeholders; can read people's emotions and flex communication style. Adjusts their approach based on different stakeholder needs, concerns, or audience member to drive alignment and meet their work goals. Effectively communicates and closely collaborates with stakeholders across commercial, compliance, legal, market access, and patient care centers to help ensure access at site of care. Builds individual account plans for key accounts and physicians including how to approach those customers, achieve sales goals, and maximize sales results. Collaborates with key accounts and physicians to drive patient identification through market development and physician education; develop a territory strategy to retain customers. Effectively utilizes resources such as programs, in-services, and in office presentations to impact territory results. Demonstrates and upholds the highest standards of integrity and compliance. Additional responsibilities as required to support business needs and organizational priorities. 4-year degree from an accredited college or university required. B2B sales experience required. 1-3 years+ of progressive and successful business experience in biotech or the specialty pharmaceutical industry. Strong interpersonal skills with the ability to build relationships and rapport with internal teams and stakeholders. Basic understanding of data analysis tools and ability to interpret simple datasets. Willingness to learn and adapt to changing environments and new methodologies under supervision. A growth mindset with the ability to treat challenges as learning opportunities. Demonstrates adherence to all company policies, industry regulations, and ethical standards, ensuring compliant business practices at all times. Excellent communication and listening skills. Collaboration: Builds foundational relationships, seeks feedback, and adapts to new methods with guidance. Customer Focus: Engages customers with empathy, delivers approved messaging based on customer needs, and starts building trust with stakeholders. Execution: Completes tasks on time, tracks performance, and begins aligning business plans with team goals and emerging trends in their territory. Critical Thinking: Learns basic data analysis, identifies opportunities, and makes small decisions with support. Must be comfortable spending 60% of time traveling; some overnight travel required including travel to Boston, congresses and within large geographical territories. Driving is an essential duty of the job; candidates must have a valid driver's license to be considered and be insurable. Must live within assigned territory.