Sarepta Therapeutics

Support patients and caregivers through education, navigation, and community engagement related to Duchenne muscular dystrophy treatments. | Requires 10+ years in healthcare or related fields, with 3+ years supporting patients directly, and strong communication skills. | Why Sarepta? Why Now? The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold a leadership position in Duchenne muscular dystrophy (Duchenne) and are building a robust portfolio of programs across muscle, central nervous system, and cardiac diseases. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne. We're looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients. What Sarepta Offers At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas: • Physical and Emotional Wellness • Financial Wellness • Support for Caregivers For a full list of our comprehensive benefits, see our website: https://www.sarepta.com/join-us The Importance of the Role Reporting to the Executive Director, Patient Engagement Liaisons, the Patient Engagement Liaison (PEL) will serve as the primary point of contact for families during the treatment discovery phase for Elevidys, providing clear, compassionate education to support informed treatment discussions with their care team. As a PEL your role involves supporting patients and caregivers interested in learning about a treatment option for Duchenne Muscular Dystrophy (DMD). This field-based position provides educational assistance to patients and caregivers considering or undergoing therapy. Key responsibilities include supporting the Duchenne community at events, collaborating with patients, families, and serving as a trusted, educational resource for patients and caregivers during the treatment consideration phase. This role is dedicated to providing an educational forum for families to learn more about Elevidys, helping them understand the therapy, available educational resources, and the broader support ecosystem. The PEL acts as a bridge between the patient community and Sarepta, ensuring families receive accurate, compassionate, and timely information to support informed decision-making. As a PEL you will work with various internal teams to meet local territory needs. The Opportunity to Make a Difference • Provide education and ongoing support to patients, caregivers, and the DMD community including Elevidys product information, dosing and administration, and other needed education • Connect patients and caregivers to relevant support programs, advocacy and community organizations • Help families navigate available options and understand next steps in their pre-treatment journey • Be accessible to address the questions of Caregivers and Patients • Create awareness and educate through local advocacy and programming, including coordinating patient programs and education at conferences • Respond promptly to patient and caregiver questions and concerns, providing resources to resolve issues, while ensuring compliance with HIPAA and patient privacy policies • Relay insights from the patient and caregiver community to internal stakeholders to help improve education and support programs More about You • Bachelor's degree plus 10 years of experience in healthcare, life sciences, social work, public health, or a related field • 3+ years of field-based experience in patient advocacy, patient support, healthcare education, or a related role • Experience directly supporting patients is required • Ability to speak empathetically and connect with patients and families facing challenging medical diagnoses • Strong communication skills including public speaking and presentation experience • Ability to explain complex information clearly and compassionately • Demonstrated ability to effectively collaborate with case managers and account managers, handle difficult patient cases, and respond promptly to patients • Overnight travel may be required. This position requires significant driving of either a company-provided or personal vehicle as well as prolonged periods of sitting, both of which are part of the essential duties and responsibilities of the role. This position will require approximately 20-50% travel, including some overnights and weekends. Preferred • Experience in neuromuscular diseases, rare diseases or gene therapy • Bi-lingual English/Spanish preferred • Experience working with patient advocacy organizations What Now? We're always looking for solution-oriented, critical thinkers. So, if you're comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply. #LI-Hybrid #LI-CM1 This position is hybrid, you will be expected to work on site at one of Sarepta's facilities in the United States and/or attend Company-sponsored in-person events from time to time. The targeted salary range for this position is $160,800 - $201,000 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta's compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity. Candidates must be authorized to work in the U.S. Sarepta Therapeutics offers a competitive compensation and benefit package. Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.

Assist in developing and optimizing high throughput workflows for bioprocess development using automated systems. | Current undergraduate or graduate student in a related scientific discipline with an interest in bioprocessing, automation, and laboratory research; experience with lab automation and proteins is a plus. | Why Sarepta? Why Now? The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold a leadership position in Duchenne muscular dystrophy (Duchenne) and are building a robust portfolio of programs across muscle, central nervous system, and cardiac diseases. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne. We’re looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients. What Sarepta Offers At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. The Importance of the Role The Intern, High Throughput Process Automation, will play a key role in advancing Sarepta’s high throughput workflows that support upstream, downstream, and analytical development within the Early Research & Process Development (ERPD) organization. This internship represents an exceptional opportunity for a student interested in biotech R&D to gain hands on experience with advanced automation technologies, including Tecan Fluent liquid handling systems, automated tangential flow filtration platforms, and high throughput purification modalities. The intern will work in a highly collaborative, cross functional environment, and will contribute to activities that directly impact Sarepta’s ability to generate critical research materials (Fabs, mAbs, proteins, and other biologics) for internal chemistry and biology partners. They will also play a key role in process development efforts for early-stage research programs. This role offers scientific mentorship, including support from team members experienced in academic and industry training. The Opportunity to Make a Difference In this role, the intern will have the opportunity to: Develop, test, and optimize workflows for the Autopulse automated tangential flow filtration instrument, enabling efficient buffer exchange and concentration of multiple therapeutic modalities (Fab, Mab, proteins, and oligo conjugates). Perform experimental design, execution, and data analysis to establish high-quality TFF workflows following ERPD pipeline updates. Support downstream process development efforts using Tecan Fluent systems in both RoboColumn and batch filter plate formats to generate critical purification data for upstream and downstream development teams. Set up, execute, and troubleshoot high throughput purification experiments to accelerate development timelines across ERPD. Collaborate closely with upstream, downstream, and analytical development groups, gaining exposure to multiple scientific disciplines and technologies. Document experimental execution and results to enhance team knowledge sharing and process reliability. Contribute to continuous improvement initiatives by identifying opportunities to improve workflow efficiency, automation robustness, and interteam collaboration. More about You Current undergraduate or graduate student in Chemical Engineering, Bioengineering, Biochemistry, Biotechnology, Biology, or related scientific discipline. Strong interest in laboratory research, bioprocess development, or automation enabled experimentation. Comfort working with complex instrumentation and a willingness to learn new automated systems and workflows. Strong analytical, problem-solving, and documentation skills. Ability to thrive in a collaborative team environment and communicate effectively with peers and mentors. Demonstrated curiosity, attention to detail, and motivation to improve laboratory processes. Preferred Qualifications Prior hands on experience with laboratory automation, liquid handlers (e.g., Tecan), or filtration systems is a plus. Experience working with proteins, antibodies, or viral vectors in an academic or industry setting. Familiarity with chromatography, filtration, or other downstream purification techniques. Program Timeline This application is for a 12-week summer internship program that will start on May 18th and conclude on August 7th, 2026. What Now? We’re always looking for solution-oriented, critical thinkers. So, if you’re comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply. #LI-OnsiteBlank This position requires work on site at one of Sarepta’s facilities in the United States. The targeted salary range for this position is $21 - $26 per hour depending upon years of education completed and nature of role. Candidates must be authorized to work in the U.S. Sarepta Therapeutics offers a competitive compensation and benefit package. Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify. Sarepta is on an urgent mission: engineer precision genetic medicine for rare diseases that devastate lives and cut futures short. We hold a leadership position in Duchenne muscular dystrophy (Duchenne) and are building a robust portfolio of programs across muscle, central nervous system, and cardiac diseases. Our deep pipeline is driven by our multi-platform technologies in siRNA, RNA and gene therapy. For more information, please visit www.sarepta.com or follow us on Twitter, LinkedIn, Instagram and Facebook.

Oversee clinical trial operations, manage vendors and CROs, and ensure compliance with regulations within a clinical research setting. | Experience in clinical research, study management, and team leadership, with knowledge of FDA/EU regulations and GCP guidelines. | Why Sarepta? Why Now? The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold a leadership position in Duchenne muscular dystrophy (Duchenne) and are building a robust portfolio of programs across muscle, central nervous system, and cardiac diseases. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne. We’re looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients. What Sarepta Offers At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas: Physical and Emotional Wellness Financial Wellness Support for Caregivers For a full list of our comprehensive benefits, see our website: https://www.sarepta.com/join-us The Importance of the Role The Associate Director, Clinical Operations Lead, is responsible for the planning, implementation, conduct, and oversight of clinical operations for assigned studies or program. This individual is expected to provide leadership as well as line management within Development Operations and guidance with regards to operational deliverables. The AD COL may lead complex studies with the support of one or more Clinical Operations Leads (COLs) and/or may be responsible for project oversight across studies within a program. The Opportunity to Make a Difference Serve as the subject matter expert within clinical operations for the planning and execution of studies across all phases May lead complex studies with the support of one or more COLs, or may provide project oversight to one or more studies on a large program Oversees Clinical Research Organizations (CROs), vendors and consultants involved with the clinical trials Serves as the point of contact for protocol execution May lead the Clinical Trial Team (CTT) and/or may participate in the program Clinical Sub Team May support the Clinical Operations Program Lead (COPL) to operationalize and execute the Clinical Development Plan (CDP) Oversees junior team members and ensures alignment with any supporting COLs assigned to studies Establishes study timelines in line with company goals and ensures accurate tracking and reporting of study metrics and progress through completion of study dashboards Works cross-functionally to ensure clinical program timelines and goals are met and risks are appropriately escalated to the COPL Ensures trial adherence to ICH/GCP/Federal and local regulations and company specific SOPs Develops, reviews and/or consults on reports and clinical trial documents such as informed consent, clinical protocols, Investigator Brochure, yearly updates to the regulatory authorities and status updates Responsible for communication and escalation of study related issues to the COPL Provides enrollment forecasting to internal stakeholder, such as Clinical Supply, at agreed upon frequency Conducts routine completeness checks of the Trial Master File (TMF) to ensure compliance with ICH/GCP and company SOPs as well as ensuring all appropriate documents are filed, or delegates activity with oversight Participates and responds to Quality Assurance and/or regulatory authority inspection audits In conjunction with CRO and appropriate internal stakeholders, facilitates the development of trial budgets and execution of clinical trial agreements and other relevant documents Manages the clinical trial budget and provides financial reporting and projections to Finance Leads creation of scope of work and budgets and escalates vendor performance issues to COPL and Procurement as necessary May serve as an escalation point for more clinical operations team study team members internally and with vendors Assume leadership role in operational improvement initiatives (e.g., SOP development, training etc.) Up to ~4 direct reports consisting of CTAs, COLs, Sr. COLs More about You Experience in management of CROs, vendors and consultants Documented training, knowledge, and application of current FDA/EU Regulations, GCP and ICH guidelines for patient registries and studies Experience developing trial plans including site management, risk mitigation strategies, trial budgets and program-level budgets Proficient written and verbal communication skills Ability to collaborate effectively with the study team, cross-functional team members and external partners (including investigator and site staff) using collaborative negotiation skills Strong computer skills including knowledge of Excel, Word, PowerPoint, Outlook and MS Project Position may require some travel Bachelor’s degree in health sciences or related field Minimum of 7+ years’ experience in clinical research with at least 5 years’ experience in study management with strong experience with study phases I-IV, global trials, and with complex trial designs Program-level experience preferred. Rare disease study management is recommended. • Line management experience required What Now? We’re always looking for solution-oriented, critical thinkers. So, if you’re comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply. #LI-Hybrid Blank This position is hybrid, you will be expected to work on site at one of Sarepta’s facilities in the United States and/or attend Company-sponsored in-person events from time to time. The targeted salary range for this position is $160,800 - $201,000 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta’s compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity. Candidates must be authorized to work in the U.S. Sarepta Therapeutics offers a competitive compensation and benefit package. Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify. Sarepta is on an urgent mission: engineer precision genetic medicine for rare diseases that devastate lives and cut futures short. We hold a leadership position in Duchenne muscular dystrophy (Duchenne) and are building a robust portfolio of programs across muscle, central nervous system, and cardiac diseases. Our deep pipeline is driven by our multi-platform technologies in siRNA, RNA and gene therapy. For more information, please visit www.sarepta.com or follow us on Twitter, LinkedIn, Instagram and Facebook.