Nuvalent, Inc.

Develop and execute thought leader engagement strategies, manage stakeholder relationships, and support brand launch initiatives in oncology. | Extensive leadership in global organizations, strong communication skills, and experience in fundraising and strategic planning; specific oncology or biopharma experience is not evident. | The Company: With deep expertise in chemistry, Nuvalent is working to create selective medicines designed with the goal to address the needs of patients with cancer. Nuvalent is an exciting early-stage company, bringing together experienced scientists and industry veterans with a proven track record in drug discovery, oncology drug development, and company building. The Role: Reporting to the Senior Director, Thought Leader Strategy & Partnerships, the Director, Thought Leader Liaison will be a pivotal partner in Nuvalent’s growing Commercial organization. This individual will spearhead the execution of the thought leader engagement as the company prepares for the market launch of Zidesamtinib and Neladalkib. The Director will be a pivotal member of the Commercial and Marketing teams. This role will provide guidance on thought leader relationships and partnerships ensuring alignment with brand objectives and coordinating end to end relationships for the Commercial organization. This individual will also support the execution of brand strategies to ensure launch readiness. Responsibilities: Develop and execute a comprehensive Commercial engagement strategy for lung cancer thought leaders, including academic researchers, digital opinion leaders, and other key influencers. Collaborate with internal teams to implement commercial strategies and manage interactions with key accounts, ensuring alignment with Nuvalent’s business goals. Capture valuable therapeutic and competitive insights from Thought Leaders and other key stakeholders to guide impactful field insights integration that shapes positioning, messaging, and stakeholder engagement strategies Work closely with the Senior Director, Thought Leader Strategy to aggregate insights and determine implications to the brand and disseminate as part of the Insights Team. Work closely with internal teams to execute commercial launch strategies, managing interactions with Thought Leaders throughout the process. Identify and engage promotional speakers to represent Nuvalent at regional and national events. Identify and nominate promotional speakers for the brand Speaker Bureau. Cultivate and maintain strong, trusting relationships with Thought Leaders, ensuring they are well-informed about Nuvalent’s activities, portfolio, and strategic direction. Partner with Legal and Compliance teams to enforce guidelines and processes for compliant customer engagement. Serve as a point of coordination, facilitating connectivity across internal stakeholders in collaboration efforts to become a preferred industry partner. Co-lead and execute Commercial Advisory Boards in partnership with Head, Thought Leader Strategy and internal cross-functional collaborators Execute the Thought Leader Engagement Congress strategy. Support brand initiatives with KOL needs (ie. KOL videos, Peer to Peer programs, Product theaters) Compliantly support Field needs to include, but not limited to: KOL introductions, speaker bureau nominations, KOL expert panels at sales meetings Competencies Include: Foster a culture of empowerment, collaboration, and a focus on patient impact. Strong scientific and clinical orientation, comfortable with data, and ability to distill complex clinical information into business implications and credible narrative with internal and external stakeholders. Exceptional communication and influence skills, with the ability to inspire confidence and work successfully with varied stakeholders including the Brand Team and Product Development Team. Proficient in multichannel marketing directed towards HCPs and patients, including digital, media, peer-to-peer, congresses, and personal promotion tactics. Drives for results and nurtures a performance-based culture of continuous improvement, addressing concerns and conflict proactively. Characteristics include being entrepreneurial, collaborative, and an energetic initiative-taker with strong interpersonal and analytical skills. Qualifications: Bachelor’s degree. Advanced degree preferable 10+ years biopharma experience including oncology launch experience 5+ years as a Thought Leader Liaison in Oncology 5+ years of commercial oncology experience in the U.S. market, with expertise in sales, marketing, or related functions. Demonstrated ability to manage multiple projects simultaneously, prioritize effectively, and communicate across all organizational levels. Proven track record of recruiting, onboarding, managing, coaching, and retaining top talent, with strong leadership and mentorship skills. Strong understanding of analytics and operations tools/technologies. Excellent written and verbal communication skills, including presentation abilities. Willingness to travel up to 50% domestically Preferred Qualifications: Experience in Lung cancer is highly preferrable Prior Thought Leader Liaison engagement and/or scientific exchange in Lung Cancer Additional Information: Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages. The targeted salary range below reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors. The range will be reviewed regularly and is subject to change. Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more. Annual Salary Range $216,000—$252,000 USD Nuvalent provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. Nuvalent is aware that many companies are dealing with fraudulent job postings on third-party employment search sites and/or individual(s) or entities claiming to be employees of such companies. Those involved are offering fraudulent employment opportunities to applicants, often asking for sensitive personal and financial information, and using such information for criminal activities. Please be advised that all legitimate correspondence from a Nuvalent employee will come from "@nuvalent.com" email accounts. Automated system response emails from our Greenhouse applicant tracking system come from a “no-reply@greenhouse.io” email address. There are no variations of these email addresses and Nuvalent would not request personal and/or financial information via email. Job opportunities would only be extended after a completed job application is submitted by a candidate and a thorough interview process including 1:1 and/or group interviews via phone, video conferencing and/or in-person. If you believe you have been contacted by anyone misrepresenting themselves as an employee of Nuvalent, please contact Nuvalent at 857-357-7000. Thank you.

Lead and validate SAS programming for clinical trial data analysis, ensuring regulatory compliance and collaboration with CROs. | Master's in a scientific/medical field, 8+ years SAS experience in clinical trials, oncology experience, familiarity with CDISC standards, and regulatory guidelines. | The Company: With deep expertise in chemistry, Nuvalent is working to create selective medicines designed with the goal to address the needs of patients with cancer. Nuvalent is an exciting early-stage company, bringing together experienced scientists and industry veterans with a proven track record in drug discovery, oncology drug development, and company building. The Role: Reporting to the Senior Director, Statistical Programming, the Associate Director, Statistical Programming will be responsible for implementing statistical analyses using SAS and performing quality review of SAS programs and deliverables for in-house analyses as well as out-sourced programming deliverables. This individual will also perform programming analyses to generate ad-hoc requests for publications and presentations. This is a remote position that will work closely with Biostatistics, Data Management, Clinical Operations, Regulatory, Global Pharmacovigilance, and other related disciplines, as well as CROs. Responsibilities: Function as lead programmer to produce and/or validate tables, listings, figures, and analysis datasets in response to regulatory requests, publication requests, and ad-hoc analyses; write specifications to describe programming needs. Develop/review TFL shells, SDTM and ADaM specifications in collaboration with biostatisticians and other clinical development colleagues. Work closely with Data Management and Biostatistics to ensure final databases, analyses, and reports are accurate. Partner with or oversee CROs or Programming vendors to perform the tasks described above. Ensure the proper collection, management, and documentation of clinical trial data according to regulatory requirements. Manages project timelines and schedules of specific phases of projects and collaborates with internal personnel and outside customer representatives. Identify problems and develop global tools that increase the efficiency and capacity of the Statistical Programming group (e.g., macros or graphical user interface applications). Competencies Include: Adaptability/Flexibility – The ability to adapt to working effectively within a variety of situations; adapts enthusiastically to organizational change and to changes in job demands. Communication and Teamwork – Ability to effectively express ideas in written and oral context; to work co-operatively with others; genuine desire to be a part of a team and contribute to organizational and team goals. Problem Solving – Ability to understand a situation or problem by breaking it down into smaller pieces using a systematic approach and to identify patterns and connections between situations that are not obviously related. Relationship Building – Builds productive working relationships and effectively communicates across a diverse spectrum of people. Organizational and results orientation – Ability to plan and handle multiple responsibilities simultaneously and still meet high quality and timeliness standards under pressure. Qualifications: Master’s Degree in statistics, mathematics, computer science, or related scientific/medical field. 8+ years of (SAS) statistical programming experience in a clinical trial setting (industry/CRO). Advanced SAS programming skills - procedures and options commonly used in clinical trials. reporting, including Macro language, BASE SAS, SAS/STAT, and SAS/GRAPH, validation/QC, experience generating listings, tables, figures. Hands-on knowledge of CDISC SDTM and ADaM models and transforming raw data into these standards. In-depth understanding of CDISC standards including SDTM and ADaM models and extensive experience of their implementation in clinical trials. Familiar with regulatory guidelines (FDA, EMA, ICH) related to clinical trials, statistics and data handling in clinical development setting, and advanced knowledge of submission requirements and standards. Experience with outsourcing programming activities and overseeing services provided by CROs and contractors. Advanced understanding of statistical concepts in support of clinical data analysis. Advanced knowledge of programming standards and processes. Oncology experience is required. Skilled at performing quality control checks of SAS code and outputs produced by other Statistical Programmers. Annual Salary Range $180,000—$210,000 USD Nuvalent provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. Nuvalent is aware that many companies are dealing with fraudulent job postings on third-party employment search sites and/or individual(s) or entities claiming to be employees of such companies. Those involved are offering fraudulent employment opportunities to applicants, often asking for sensitive personal and financial information, and using such information for criminal activities. Please be advised that all legitimate correspondence from a Nuvalent employee will come from "@nuvalent.com" email accounts. Automated system response emails from our Greenhouse applicant tracking system come from a “no-reply@greenhouse.io” email address. There are no variations of these email addresses and Nuvalent would not request personal and/or financial information via email. Job opportunities would only be extended after a completed job application is submitted by a candidate and a thorough interview process including 1:1 and/or group interviews via phone, video conferencing and/or in-person. If you believe you have been contacted by anyone misrepresenting themselves as an employee of Nuvalent, please contact Nuvalent at 857-357-7000. Thank you.

Support patient access strategies, educate healthcare providers, and resolve reimbursement barriers in oncology settings. | Extensive experience in oncology reimbursement, strong provider engagement skills, and knowledge of billing/coding for specialty drugs. | The Company: With deep expertise in chemistry, Nuvalent is working to create selective medicines designed with the goal to address the needs of patients with cancer. Nuvalent is an exciting early-stage company, bringing together experienced scientists and industry veterans with a proven track record in drug discovery, oncology drug development, and company building. The Role: Reporting to the Director, Patient Access Services, the Associate Director, Access & Reimbursement (ADAR) will be a critical member of the Market Access team to create patient impact by providing field access support and education to healthcare professionals (HCPs), helping to maximize patient access to products. This role will be an empowered and confident subject matter expert in supporting complex patient cases through understanding the payer landscape, customer engagement, and internal cross-functional collaboration. This role will support the patient access strategy and operations, working closely with the Patient Support (PS) team on patient cases and program oversight. We are seeking an innovative leader with deep expertise in new launches, specialty oncology access, healthcare staff engagement, and patient services. Responsibilities: Provides education to HCPs and their staff on payer-specific coverage criteria and documentation requirements to help address access and reimbursement barriers for prescriptions already in progress. Delivers guidance on access support, including processes, forms, payer-related coverage challenges, and the Nuvalent patient financial support programs. Educate HCP staff on patient support (PS) programs, resources, enrollment processes, and application updates so that they are informed on how to use our PS offerings & status of their patients. Proactively identify and help to resolve payer, account, and patient access barriers using data-driven insights, dashboards, and cross-functional collaboration. As the PS & payer landscape subject matter expert, coordinate with specialty pharmacy, PS operations, payer, market access, medical affairs, and other cross-functional colleagues to support patient access. Triage and resolve patient support related questions and access concerns escalated from field teams, ensuring timely and compliant resolution. Educate and inform regional field facing teams on PS programs, geographical payer nuances, access challenge trends, and program insights. Develop internal and external access tools & training materials. Develop patient access and reimbursement strategies with cross-functional teams, while monitoring regulatory, payer & industry trends, to proactively & compliantly address access challenges. Support oversight of patient support programs (financial assistance & non-commercial specialty pharmacy); ensuring accountability for positive customer impact & excellence. Coordinate regularly with PS operations teams on patient case updates and escalate as required. Competencies Include: Demonstrated passion for improving patient access and outcomes. Problem-Solving: Proactive approach to resolving complex access issues. Analytical Skills: Ability to interpret coverage trends & payer policies to identify barriers and implement solution-oriented strategies to optimize patient access. Business Acumen: In-depth understanding prior authorization, coding, billing, patient services, and specialty pharmacy processes. Provider Engagement: Building strong relationships with healthcare providers and office Highly responsive; ability to support escalations outside of local time zone working hours, as needed. Cross-Functional Collaboration: Partnering with sales, market access, patient services, and medical affairs. Foster a culture of empowerment, collaboration, and a focus on patient impact. Team Leadership: Proven leadership and conflict resolution skills. Encourage collaboration, innovation, and new ideas while integrating information from various sources. Clear Communication: Highly effective presentation, communication, emotional intelligence, and facilitation & interpersonal skills.Ability to explain complex reimbursement processes in simple terms. Process Improvement: Identifying opportunities to streamline reimbursement workflows. Adaptability: Managing evolving payer landscapes and policy changes. Qualifications: Bachelor's degree is required. 8+ years of biopharma experience, including. 3+ years of oncology field reimbursement manager (FRM) / or access reimbursement manager (ARM) experience with established relationships at major oncology centers across the country. Extensive experience in oral / specialty oncology access, rare disease launch, program implementation, and payer navigation. Demonstrated excellence in customer engagement. Previous experience supporting HCP staff through complex reimbursement barriers, prior authorizations, appeals, and providing education. Knowledge of all national health insurers (commercial & government) including billing/coding. Highly organized, team player, excellent communicator, problem solver, and presenter. Able to work effectively & autonomously through ambiguity. All activities must comply with HIPAA, OIG, FDA regulations, and Nuvalent policies. This is a non-promotional role. Previous experience in a clinical role, NSCLC, Patient Services program oversight, & vendor management preferred. Prior Authorization Certified Specialist preferred. Willingness to travel domestically up to 20% (customer engagements, internal & vendor meetings). Additional Information: Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages. The targeted salary range below reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors. The range will be reviewed regularly and is subject to change. Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more. Annual Salary Range $185,000—$210,000 USD Nuvalent provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. Nuvalent is aware that many companies are dealing with fraudulent job postings on third-party employment search sites and/or individual(s) or entities claiming to be employees of such companies. Those involved are offering fraudulent employment opportunities to applicants, often asking for sensitive personal and financial information, and using such information for criminal activities. Please be advised that all legitimate correspondence from a Nuvalent employee will come from "@nuvalent.com" email accounts. Automated system response emails from our Greenhouse applicant tracking system come from a “no-reply@greenhouse.io” email address. There are no variations of these email addresses and Nuvalent would not request personal and/or financial information via email. Job opportunities would only be extended after a completed job application is submitted by a candidate and a thorough interview process including 1:1 and/or group interviews via phone, video conferencing and/or in-person. If you believe you have been contacted by anyone misrepresenting themselves as an employee of Nuvalent, please contact Nuvalent at 857-357-7000. Thank you.

Support financial planning, reporting, and analysis to enable sound business decisions in a biotech company. | Bachelor's in Finance or related field, 8+ years in financial reporting and analysis, experience supporting R&D and commercial teams, system savvy, strong communication skills. | The Company: With deep expertise in chemistry, Nuvalent is working to create selective medicines designed with the goal to address the needs of patients with cancer. Nuvalent is an exciting early-stage company, bringing together experienced scientists and industry veterans with a proven track record in drug discovery, oncology drug development, and company building. The Role: Reporting to the Vice President of Financial Planning & Analysis (FP&A), the Associate Director, FP&A will play a pivotal role in Nuvalent’s continued growth. The Associate Director, FP&A will be a hands-on key contributor to the financial planning and reporting process at Nuvalent. Working closely with stakeholders across the organization, this is a highly visible role that will be responsible for supporting the growing portfolio of Nuvalent’s discovery, development and pre-commercial programs by enabling effective financial forecasting, reporting and analysis of operating results to enable sound business decisions. The ideal candidate is a results-oriented, self-starter who is looking to join a rapidly growing company. Responsibilities: Partner closely with Finance & various business teams to provide effective planning and analysis; provide senior leadership & business partners with appropriate tools and analysis to establish goals and measure performance Manage budgeting, forecasting, and planning initiatives throughout the company, including monthly, quarterly, and annual financial reporting packages and budget to actual analysis Lead the design, build & implementation of internal performance management reporting us BI tools to ensure appropriate level of visibility to OPEX, headcount, purchase orders etc. Assessment of key stakeholder needs, training & change management is within the scope of this role Participate in the development and implementation of new processes to support the successful completion of timely and accurate forecasts and tracking of key investments and performance metrics Maintain Nuvalent’s financial planning systems, models & reporting to ensure they are both accurate and updated to reflect latest assumptions and changing business needs Contribute to the accounting monthly close process. Collaborate with cross-functional teams to meet monthly close timeline while adhering to internal controls Provide support to the department leaders across the organization, to increase transparency around key financial results and assumptions, including spending controls/limits and forecasting Provide input to presentations for the leadership team and the board of directors Ad-hoc financial projects as assigned Competencies Include: Strong interpersonal skills to collaborate, influence and build credibility with business partners across the organization Passion for designing, implementing & streamlining systems, processes & reporting, with attention to detail & accuracy Thrive with constant change & continuous improvement, "rolling up sleeves", performing in a fast-paced, dynamic work environment Strong analytical skills coupled with ability to make recommendations for changes as needed High level of integrity and principles that embrace transparency and ethics Results orientated work ethic and a positive, can-do attitude Qualifications: Bachelor’s in Finance, Accounting or relevant degree, MBA preferred 8+ years of progressive financial reporting, planning and analysis experience in the pharmaceutical or biotechnology industry Prior experience supporting R&D and commercial organizations and/or teams is highly preferred System savvy, ideally with experience implementing or overseeing financial planning and reporting tools. Experience with NetSuite is a plus Strong communications skills and executive presence Excellent Excel, PowerPoint, and analytical skills Additional Information: Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages. The targeted salary range below reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors. The range will be reviewed regularly and is subject to change. Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more. Annual Salary Range $165,000—$200,000 USD Nuvalent provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. Nuvalent is aware that many companies are dealing with fraudulent job postings on third-party employment search sites and/or individual(s) or entities claiming to be employees of such companies. Those involved are offering fraudulent employment opportunities to applicants, often asking for sensitive personal and financial information, and using such information for criminal activities. Please be advised that all legitimate correspondence from a Nuvalent employee will come from "@nuvalent.com" email accounts. Automated system response emails from our Greenhouse applicant tracking system come from a “no-reply@greenhouse.io” email address. There are no variations of these email addresses and Nuvalent would not request personal and/or financial information via email. Job opportunities would only be extended after a completed job application is submitted by a candidate and a thorough interview process including 1:1 and/or group interviews via phone, video conferencing and/or in-person. If you believe you have been contacted by anyone misrepresenting themselves as an employee of Nuvalent, please contact Nuvalent at 857-357-7000. Thank you.

Lead U.S. and global HEOR strategy, oversee evidence generation, and collaborate across functions to support drug development and market access. | Requires a PhD or MD with 7-10+ years in pharma/biotech HEOR/RWE, oncology experience, and expertise in payer landscapes and modeling. | The Company: With deep expertise in chemistry, Nuvalent is working to create selective medicines designed with the goal to address the needs of patients with cancer. Nuvalent is an exciting early-stage company, bringing together experienced scientists and industry veterans with a proven track record in drug discovery, oncology drug development, and company building. Title: Director, Health Economics & Outcomes Research (HEOR) The Company: With deep expertise in chemistry, Nuvalent is creating selective medicines to address the needs of patients with cancer. Nuvalent is an exciting early-stage company, bringing together experienced scientists and industry veterans with a proven track record in drug discovery, oncology drug development, and company building. The Role: Reporting to the Senior Director, HEOR, the Director of Health Economics & Outcomes Research will lead U.S. and Global HEOR strategy for Nuvalent’s portfolio, shaping value evidence to enable optimal patient access and inform coverage, reimbursement, and utilization decisions. You will design and deliver HEOR/RWE studies, develop payer-facing economic/decision tools, support pre-, peri-, and post-launch planning, and foster cross-functional collaboration across Medical Affairs, Market Access, Regulatory, Commercial, Clinical Development, and Biostatistics. You’ll also play a visible role educating the organization on the evolving U.S. and Global HTA environment. This is an ideal opportunity for a scientifically strong, execution-oriented leader who enjoys pairing strategic planning with hands-on delivery in a fast-paced setting. Responsibilities: Strategy, Governance & Planning Lead the U.S. & Global HEOR strategy and integrated evidence planning for Nuvalent assets, aligned with Medical Affairs, Market Access, Regulatory, and Commercial priorities. Standardize and optimize data generation policies, processes, and SOPs to ensure quality, compliance, and scalability. Develop the annual HEOR tactical plan and budget; manage timelines, vendors, and scope to achieve defined objectives. Serve as the internal HEOR point of contact for evidence generation needs, services, and technologies; proactively represent payer/IDN evidence needs in cross-functional planning. Educate and upskill teams on HEOR, evidence-based medicine, U.S. reimbursement trends, and Global HTA dynamics. Evidence Generation & Publications Design, lead, and complete HEOR/RWE studies (e.g., observational studies, claims/EMR/registry analyses, PRO development/validation, burden of illness, unmet need). Own research plans, protocols, budgets, and timelines; oversee analyses and author abstracts, posters, manuscripts, and internal reports. Partner with Clinical Development and Biostatistics/Evidence Generation to optimize study design, endpoints, data sources, and analyses. Collaborate with Medical Information/Scientific Communications to inform U.S./Global publication plans and ensure consistent, compliant value messaging. Economic & Decision-Support Tools Lead development of AMCP/Global dossiers, Budget Impact Models (BIMs), Cost-Effectiveness Analyses (CEA), ITCs/NMAs, Systematic Literature Reviews (SLRs), and payer pull-through materials. Support ICER assessments and responses (as applicable) and monitor HTA implications (e.g., NICE, CADTH, etc.) for brand strategy. External Engagement & Field Support Identify and collaborate with KOLs/COEs on study design, authorship, and advisory boards; conduct payer advisory boards to track evolving evidence requirements. Engage payers, IDNs, PBMs, specialty pharmacies, and other decision makers via compliant scientific exchange to inform evidence needs and communicate value. Provide field-based scientific/HEOR support and tools to Market Access and medical field teams. Cross-Functional Partnership & Launch Excellence Partner with Brand/Commercial and Market Access to shape value narratives and pull-through while maintaining scientific integrity and compliance. Contribute to or lead high-priority medical initiatives, integrated evidence planning workshops, advisory boards, and cross-functional launch planning across U.S. and Global teams. Maintain in-depth knowledge of the evolving healthcare environment and HTA to anticipate evidence needs and inform strategy. Competencies: Strategic & hands-on: Equally comfortable setting strategy and rolling up sleeves to deliver. Collaboration & influence: Builds trust and productive relationships with internal leaders and external stakeholders. Innovation & problem solving: Encourages new ideas; integrates evidence from multiple sources to drive decisions. Operational excellence: Creates scalable capabilities, processes, and procedures; manages ambiguity and complexity. Results orientation: Performance-driven; proactively addresses risks, conflicts, and tradeoffs to deliver on time and on budget. Executive communication: Translates complex science and economics into clear, business-relevant insights. Qualifications: Doctoral degree (PhD, PharmD, MD/DO). 7–10+ years of relevant pharma/biotech HEOR/RWE experience. Oncology experience (3+ years), preferably NSCLC; U.S. and Global launch experience. Demonstrated expertise with U.S. and Global RWD (claims, EMR, registries) and payer landscapes. Hands-on experience with HEOR modeling (BIM/CEA), observational methods, and PROs; familiarity with statistics. Proven ability to work independently and collaboratively in fast-paced, cross-functional environments and manage multiple complex projects. Outstanding communication and presentation skills, including executive-level briefings and external thought leader engagement. U.S.-based remote role with periodic travel for internal meetings, congresses, advisory boards, and select payer/KOL engagements (~10–20% domestic; occasional international as needed). Preferred Experience supporting ICER and engaging with Global HTA bodies (e.g., NICE, CADTH). Track record building departmental capabilities, SOPs, and scalable vendor/operational frameworks. Established relationships across payers/IDNs/PBMs and oncology KOLs/COEs. Knowledge of medical communications trends and best practices. Additional Information: Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with competitive total rewards packages. The targeted salary range below reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors. The range will be reviewed regularly and is subject to change. Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401(k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more. Nuvalent provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. Annual Salary Range $220,000—$250,000 USD Nuvalent provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. Nuvalent is aware that many companies are dealing with fraudulent job postings on third-party employment search sites and/or individual(s) or entities claiming to be employees of such companies. Those involved are offering fraudulent employment opportunities to applicants, often asking for sensitive personal and financial information, and using such information for criminal activities. Please be advised that all legitimate correspondence from a Nuvalent employee will come from "@nuvalent.com" email accounts. Automated system response emails from our Greenhouse applicant tracking system come from a “no-reply@greenhouse.io” email address. There are no variations of these email addresses and Nuvalent would not request personal and/or financial information via email. Job opportunities would only be extended after a completed job application is submitted by a candidate and a thorough interview process including 1:1 and/or group interviews via phone, video conferencing and/or in-person. If you believe you have been contacted by anyone misrepresenting themselves as an employee of Nuvalent, please contact Nuvalent at 857-357-7000. Thank you.

Lead publication and communication strategies, collaborate cross-functionally, and manage publication development and vendor relationships. | Requires an advanced scientific degree, 8+ years in pharma/biotech, 4+ years in publications, oncology experience, and strong project management skills. | Job Description: • Lead asset publication and communications strategy, planning, and execution • Collaborate cross-functionally on publication planning and execution • Partner with Clinical Development, Medical Affairs, Evidence Generation, and Brand teams to identify and prioritize data gaps and publication concepts • Co-lead Publication Planning Committee, including driving agendas, documenting meeting minutes, and managing action items • Manage approval of publication strategy and plans by the Publication Planning Committee and endorsement by PDT and LT • Oversee all aspects of publication development for abstracts, congress presentations, manuscripts, reviews, publication extenders, etc. • Critically review drafts and adjudicate comments • Drive development and updates of the asset scientific platform and lexicon in collaboration with cross-functional teams; ensure utilization to drive consistency across all related medical materials and channels • Support portfolio-wide publications as needed • Publication management platform oversight (eg, Datavision or similar platform) • Support data dissemination strategy and plans across various Medical Affairs initiatives, including content development, congress activities, and medical education initiatives. • Subject matter expert on disease state, competitive landscape, and publication benchmarks • Manage vendors, ensuring adherence to timelines, process, and publication best practices Requirements: • Advanced degree (PhD, PharmD, MD/DO, NP, PA-C or equivalent) in a relevant scientific discipline • 8+ years of experience in the pharmaceutical biotech or other relevant industries • 4 years of experience in publications • Demonstrated experience developing and executing publication strategy and plans • Oncology experience required; lung cancer experience strongly preferred • Experience managing medical communications vendors • In-depth knowledge of GPP and ICMJE criteria. • Strong project management skills, with high attention to detail and ability to prioritize and deliver multiple projects simultaneously. • Effective oral, written, and interpersonal skills required. Benefits: • medical, dental, and vision insurance • 401(k) retirement savings plan • generous paid time off (including a summer and winter company shutdown)

Support virtual engagement and data-driven outreach to healthcare professionals within a specified region, leveraging insights to optimize engagement strategies. | Minimum 5 years of healthcare or oncology-related experience, proficiency in data management and virtual communication tools, and strong interpersonal skills. | The Company With deep expertise in chemistry, Nuvalent is working to create selective medicines designed with the goal to address the needs of patients with cancer. Nuvalent is an exciting early-stage company, bringing together experienced scientists and industry veterans with a proven track record in drug discovery, oncology drug development, and company building. This role is remote / field-based, and candidates must live within the assigned region to effectively cover the geography. This region will cover the following states: AL, DC, DE, FL, GA, MD, MS, NC, PR, SC, VA The Role Reporting to the Senior Director of Precision Engagement, the Senior Precision Engagement Manager will play a key role along with our Regional Business Leaders and Oncology Account managers to impact primarily through virtual engagement across regionally prioritized HCPs and geographies through a blend of data-driven decision-making, brand promotion, and collaborative regional support. This role is designed for individuals who thrive in dynamic environments, are energized by data, and can balance strategic thinking with tactical execution. Responsibilities Brand Promotion and Virtual Engagement • Promote Nuvalent products virtually across a defined geography, prioritizing outreach to targeted HCPs. • In territory promotion as strategically applicable • Expand team reach by covering lower-potential HCPs that may not be addressed through traditional field roles. • Strategically support Regional Business Directors and Oncology Account Managers to maximize their field effectiveness through supplemental virtual interactions. Processing Data Intelligence to support patient finding • Synthesize multiple data streams to determine the relevance of data and triangulate data into possible lead generation • Ingest and filter broad data sets to identify relevant insights and quality leads for follow-up. • Continuously assess intelligence to prioritize accounts and deliver impactful engagement strategies. Provide Region support • Provide additional support for RBDs and OAMs by identifying regional opportunities and facilitating HCP access. • Engage in regional oversight activities including patient-following efforts, regional segmentation, and engagement gap assessments. Competencies Include • Drives for results- creates and nurtures a performance-based culture of continuous improvement, addressing concerns and conflict proactively. • Foster a culture of empowerment, collaboration, and a focus on patient impact. • Exceptional communication and influence skills, with the ability to inspire confidence and work successfully with varied stakeholders. • Characteristics include being entrepreneurial, collaborative, and an energetic self-starter with strong interpersonal and analytical skills. Loves the challenge of creating stories from data and sees ambiguity as an opportunity. • Believing meticulous details lead to better outcomes and acts with urgency even when the need isn’t apparent. • Digitally savvy and naturally inclined to explore and leverage digital tools. • Values achieved as a team and communicates clearly across multiple stakeholders. • Comfortable navigating cold outreach and virtual relationships in a compliant, professional manner. • Open-minded and curious, always striving to learn and improve. Qualifications • Bachelor’s degree required; advanced degree (MBA, PharmD, NP, MS, or related) preferred. • Minimum of 5 years of pharmaceutical sales (oncology preferred), health care triage, or direct patient care experience in oncology (lung cancer). • Strong analytical and interpersonal skills. • Experience and competence using virtual meeting platforms. • Proficiency managing data and insights in a CRM or patient record database/charts. • Ability to work outside traditional hours with evening and weekend hours to cover calls and engagements across time zones. • Travel expectations will be ~10%. • Demonstrated organizational skills to manage multiple projects simultaneously, prioritize projects effectively, and communicate with cross-functional partners • Strong written and verbal communication skills (including presentation skills) Additional Information Nuvalent is committed to fair and equitable compensation practices, aiming to provide employees with market-competitive total rewards packages. The targeted salary range below reflects what Nuvalent reasonably and in good faith expects to offer for this position at the time of posting, but the final salary determination may be within or outside this range based on various factors, including, but not limited to, experience, skills, education, and market factors. The range will be reviewed regularly and is subject to change. Nuvalent also offers a comprehensive benefit package to support our employees at each stage of their career, financial, health, and well-being journey, including medical, dental, and vision insurance, 401 (k) retirement savings plan, generous paid time off (including a summer and winter company shutdown), and much more. Annual Salary Range $195,000—$215,000 USD Nuvalent provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. Nuvalent is aware that many companies are dealing with fraudulent job postings on third-party employment search sites and/or individual(s) or entities claiming to be employees of such companies. Those involved are offering fraudulent employment opportunities to applicants, often asking for sensitive personal and financial information, and using such information for criminal activities. Please be advised that all legitimate correspondence from a Nuvalent employee will come from "@nuvalent.com" email accounts. Automated system response emails from our Greenhouse applicant tracking system come from a “no-reply@greenhouse.io” email address. There are no variations of these email addresses and Nuvalent would not request personal and/or financial information via email. Job opportunities would only be extended after a completed job application is submitted by a candidate and a thorough interview process including 1:1 and/or group interviews via phone, video conferencing and/or in-person. If you believe you have been contacted by anyone misrepresenting themselves as an employee of Nuvalent, please contact Nuvalent at 857-357-7000. Thank you.