Loyal

Leading and unifying development programs, ensuring regulatory alignment, and mentoring teams. | Proven executive leadership in biotech or animal pharma, experience leading programs from candidate to NDA/BLA approval, and ability to operate at both strategic and tactical levels. | About Loyal Loyal is a clinical-stage veterinary medicine company developing longevity drugs for dogs. Our mission is to help dogs live longer, healthier lives. We're pioneering a new category of veterinary prescription drugs that proactively and preventatively target the underlying drivers of aging, delaying the onset of disease and preserving quality of life as dogs age. We've already made significant progress in our mission to develop the first FDA-approved drugs to extend canine lifespan: as of early 2026 we've completed two of three major FDA review sections for our lead program, LOY-002, and are targeting submission of the third and final section later this year. Loyal is a well-funded startup with teams of scientists, veterinarians, engineers, operators, and creatives. You'll help us continue on our path of earning FDA approval for the first lifespan extension medicine for any species — and change what's possible for the dogs we love. About the role You will be responsible for advancing Loyal’s portfolio – from program establishment through regulatory approval. In addition to directly supervising Product Leaders & Regulatory Affairs, you will provide matrix support to clinical & CMC functions. You will report to the CEO and serve on the executive team of Loyal. Your daily work will include Program Leadership: Provide the unifying voice for all development programs. Identify resource/communication gaps. Demand cross-functional exchange and integration. Ensure clarity on program status/timeline across the company. Mentor/coach Program Leaders (who serve as mini-CEOs of individual programs). Regulatory affairs (including CMC): Ensure cross-functional alignment on regulatory strategy. Own filings, meetings & communications with regulatory agencies (CVM is the initial & sole focus). Provide regulatory perspectives to clinical, research, CMC & commercial functions based on prior experience with regulatory agencies. Assess & incorporate (if appropriate) advisor feedback into regulatory & CMC strategy. Mentor/coach regulatory affairs team members. Matrix leadership support for clinical/vet research, CMC and commercial functions Work closely with Chief Veterinarian, Chief Technical Operations Officer & Chief Commercial Officer to integrate respective activities into overall program goals. About you Proven track record as an executive leader in a small (~50-200 FTE) biotech company; prior animal pharma experience not essential Have led programs from candidate nomination through NDA/BLA approval Can readily flex between board-level strategy & daily operational issues: serve as a visionary but also DELIGHTED to dig deep into raw data Comfortable with 180-degree turns in (data-driven) strategic or tactical plans Unifier, but also able to disagree (without being overly disagreeable) Look forward to thriving (learning) in a Silicon Valley-style, Gen Z-predominant work environment Salary Range: $300,000 - $400,000 Loyal benefits Full-coverage health insurance — medical, dental and vision — for you and your dependents $1,000 home office equipment stipend $1,200/year learning budget for books, courses, etc. $250/month wellness budget for gym, cleaners, spa, food, etc. All 3-day weekends are turned into 4-day weekends 🎉 Unlimited vacation and paid holidays Paw-ternity leave — adopt a dog and get a day off with your new family member 🐶 Competitive salary Company equity options grant for new hires Loyal is founded and led by a first-gen female CEO and is proud to be an equal opportunity employer. We do not discriminate against applicants based on gender, race or color, ethnicity or national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, or any other applicable characteristics protected by law. Our values Lean into moonshots We don’t settle for incremental change. We have the bravery to take risks and shoot for the impact we want to have. Opportunity is at the intersection We lean into combining disciplines, expertises, and perspectives not normally adjacent. We design our organization to facilitate cross-pollination and cross-collaboration. We reject silos. Expertise without ego Titles do not determine who has a voice. We work on hard technical problems and have a ton of fun while at it. Learning by doing Our path is novel and many things we are doing have never been done before. We lean into MVPs and are open to unexpected outcomes. Lead with context We value leading with context. We equip people with the context and background necessary to make their own decisions and act in the best interest of Loyal. We empower teams to succeed. Empathy and respect for all life Our patients are not just numbers. Our work is intentional, thoughtful, and guided by respect for life. We take our responsibility to pets and pet parents seriously.

Support the CEO in strategic, operational, and communication tasks to enhance organizational effectiveness. | Requires biotech or life sciences background, top-tier writing skills, first-principles thinking, and early-career experience. | About Loyal Loyal is a clinical-stage veterinary medicine company developing longevity drugs for dogs. Our mission is to help dogs live longer, healthier lives. We're pioneering a new category of veterinary prescription drugs that proactively and preventatively target the underlying drivers of aging, delaying the onset of disease and preserving quality of life as dogs age. We've already made significant progress in our mission to develop the first FDA-approved drugs to extend canine lifespan: as of early 2026 we've completed two of three major FDA review sections for our lead program, LOY-002, and are targeting submission of the third and final section later this year. Loyal is a well-funded startup with teams of scientists, veterinarians, engineers, operators, and creatives. You'll help us continue on our path of earning FDA approval for the first lifespan extension medicine for any species — and change what's possible for the dogs we love. About the role We’re seeking an experienced Operations Generalist in the Office of the CEO. We’re looking for an Operations Generalist to work directly with our Founder/CEO Celine to multiply her capacity and execute whatever is the highest priority that month - strategy, operations, special projects, comms, fundraising, and building new functions from scratch. This role is for someone who is hungry, has an exceptional writing bar, thinks in first principles, and is comfortable jumping into messy, ambiguous work and turning it into crisp decisions and execution. You must be willing to work with the CEOs schedule (usually calls and team meetings during the day, and IC work in the evenings). You must have an extremely low ego, be extremely organized, autonomous, and high growth. This is a great role for an early-career individual who wants to accelerate their growth, perhaps to become a founder themselves in a couple of years or another operator role. You must be willing to do all manners of work, from administrative to strategic leadership. This is not an executive or leadership role. What you’ll do Be the CEO’s force multiplier: your number one job is to make Celine a better CEO for the team, company, and mission. Research: you’ll set up Celine for success in partnership calls, meetings, interviews, conferences, regulatory interactions, etc. Problem solving sprints: you’ll run on diverse problems across the organization. Board + investor execution: draft board decks, memos, and investor updates with clarity and strong narrative. CEO comms: prepare internal comms—All Paws decks, workshops, leadership updates, and key messages. Fundraising support: shadow and support Celine across fundraising workstreams (including the unglamorous but critical parts). Triage + admin support: manage CEO to-dos and priorities, collaborate tightly with the EA, and handle selective email triage/writing. What we’re looking for Early career: you are likely in the first three to five years of your post-academic career. Bio background required (biotech, life sciences, pharma, or adjacent). You can speak to the intersection of biological sciences and business. Top-tier writer: you can produce CEO-ready decks/memos/emails that are crisp, structured, and persuasive. First-principles thinker: you reason from facts, ask the right questions, and avoid cargo-cult processes. 0 →1 operator: you can stand up “v1” quickly and iterate fast based on feedback. You proactively seek out feedback and can handle it with ease and depersonalization. Strong judgment + ownership: you know what matters, what can wait, and when to escalate. Influence without authority: you can drive outcomes across teams through relationships, clarity, and follow-through. High EQ: you can read a room, represent the CEO well, and create healthy discomfort when needed. Comfort with numbers: solid quantitative reasoning (models, spreadsheets, pressure-testing assumptions). Highly organized: you can track many parallel threads without dropping balls. You are extremely reliable and will not need micromanagement (and will likely resent any attempt at it). Salary Range: $100,000 - $150,000 Loyal benefits Full-coverage health insurance — medical, dental and vision — for you and your dependents $1,000 home office equipment stipend $1,200/year learning budget for books, courses, etc. $250/month wellness budget for gym, cleaners, spa, food, etc. All 3-day weekends are turned into 4-day weekends 🎉 Unlimited vacation and paid holidays Paw-ternity leave — adopt a dog and get a day off with your new family member 🐶 Competitive salary Company equity options grant for new hires Loyal is founded and led by a first-gen female CEO and is proud to be an equal opportunity employer. We do not discriminate against applicants based on gender, race or color, ethnicity or national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, or any other applicable characteristics protected by law. Our values Lean into moonshots We don’t settle for incremental change. We have the bravery to take risks and shoot for the impact we want to have. Opportunity is at the intersection We lean into combining disciplines, expertises, and perspectives not normally adjacent. We design our organization to facilitate cross-pollination and cross-collaboration. We reject silos. Expertise without ego Titles do not determine who has a voice. We work on hard technical problems and have a ton of fun while at it. Learning by doing Our path is novel and many things we are doing have never been done before. We lean into MVPs and are open to unexpected outcomes. Lead with context We value leading with context. We equip people with the context and background necessary to make their own decisions and act in the best interest of Loyal. We empower teams to succeed. Empathy and respect for all life Our patients are not just numbers. Our work is intentional, thoughtful, and guided by respect for life. We take our responsibility to pets and pet parents seriously.

Lead and oversee analytical development and QC lifecycle for small-molecule pharmaceuticals, ensuring regulatory compliance and strategic alignment. | Requires 18+ years in pharmaceutical analytical development and QC, with leadership experience, deep regulatory knowledge, and expertise in GMP operations. | Job Description: • Set and execute the global analytical development and quality control strategy aligned with Loyal’s corporate and CMC objectives. • Own the end-to-end analytical and QC lifecycle from early development through commercialization, including commercial QC readiness, product release, stability programs, and post-approval lifecycle management. • Serve as the accountable executive for GMP analytical and QC operations, ensuring inspection-ready systems and sustained regulatory compliance. • Act as a senior CMC leader on cross-functional program teams, influencing development strategy, timelines, and investment decisions. • Lead the development, validation, transfer, and lifecycle management of analytical methods and control strategies, with immediate focus on small-molecule oral solid dosage products, while supporting additional modalities as the pipeline evolves. • Lead cross-functional identification and lifecycle management of CQAs, specifications, and control strategies. • Establish and oversee commercial QC operations, including governance of external GMP testing laboratories and service providers. • Provide executive oversight of deviations, investigations, OOS/OOT events, and CAPAs related to analytical and QC activities. • Serve as a senior analytical subject-matter expert in interactions with FDA Center for Veterinary Medicine (CVM) and other global animal health regulatory agencies, including regulatory submissions, responses, and inspections. • Select, manage, and govern external analytical laboratories, CDMOs (as applicable), and other partners to ensure technical performance, compliance, and cost effectiveness. • Build, scale, and lead a high-performing QC and analytical development organization, including hiring, mentoring, and developing senior technical leaders. • Establish operating models that balance internal capabilities with strategic outsourcing to support a growing and commercial portfolio. • Manage resource planning, aligning analytical and QC investments with pipeline priorities and long-term business objectives. Requirements: • Ph.D., M.S., or B.S. in Analytical Chemistry, Chemistry, or a related scientific discipline. • 18+ years of progressive experience in analytical development and quality control for pharmaceutical products, with deep expertise in small-molecule oral solid dosage forms. • Demonstrated experience spanning early development, clinical programs, commercial launch, and post-approval lifecycle management. • Proven success building and leading analytical and/or QC organizations, including hiring, mentoring, and developing senior technical leaders. • Extensive experience with analytical method development, phase-appropriate validation, method transfer, and GMP QC operations. • Strong knowledge of animal health regulatory requirements, including FDA CVM and relevant global guidelines (e.g., VICH; ICH as applicable), with direct experience supporting regulatory submissions and inspections. • Track record of effective oversight of external GMP testing laboratories and analytical service providers, including governance, performance management, and quality issue resolution. • Strategic mindset with the ability to translate scientific and regulatory complexity into clear, actionable business recommendations. • Comfortable operating in a fast-paced, growth-stage environment, balancing hands-on technical leadership with executive-level decision-making. • Excellent communication and influencing skills, with the ability to engage credibly with executive leadership, regulators, and external partners. Benefits: • Full-coverage health insurance — medical, dental and vision — for you and your dependents • $1,000 home office equipment stipend • $1,200/year learning budget for books, courses, etc. • $250/month wellness budget for gym, cleaners, spa, food, etc. • All 3-day weekends are turned into 4-day weekends 🎉 • Unlimited vacation and paid holidays • Paw-ternity leave — adopt a dog and get a day off with your new family member 🐶 • Competitive salary • Company equity options grant for new hires

Lead program management activities to drive FDA approval timelines, coordinate cross-functional teams, manage risks and escalations, and communicate status to executives. | 10+ years pharmaceutical or life science experience, bachelor's degree in science/engineering/health, strong program management skills, and ability to lead and coach teams. | About Loyal Loyal is a clinical-stage veterinary medicine company developing drugs intended to extend the lifespan and healthspan of dogs. Our mission is to help dogs live longer, healthier lives. We've already achieved significant milestones on our path to earning FDA approval for the first lifespan extension drug for any species. We have three products in our pipeline and are on track for FDA conditional approval within the next year. Loyal is a well-funded startup in growth mode. Our team includes scientists, veterinarians, engineers, operators, and creatives. This role will play a key role in supporting our growth strategies. About The Role The Senior Director, Program Manager will play a pivotal role in bringing one of our longevity drug pipelines through FDA approval and expanding Loyal's portfolio. You will be the go-to point of contact for all program-related activities, lead the program team in formulating strategies that align with corporate goals, and lead efforts in building and scaling the program management/project management infrastructure. You will work closely with the senior executive team. This role is for someone looking to leverage their knowledge of program management to help transform Loyal into a commercial enterprise. The ideal candidate is a highly collaborative team player and requires strategic leadership, strong interpersonal and communication skills, and a willingness to learn multiple disciplines. You will report to our Chief R&D Officer. Your daily work will include: • Serve as the program spokesperson. • Own program timeline, understand dependencies, and ensure alignment with regulatory requirements. • Lead cross-functional discussions to ensure timely and proactive discussions around risks, status, opportunities, and mitigation/acceleration strategies. • Work closely with functional leads to ensure team projects are completed on time, within budget, and maintain quality standards. • Escalate program issues that can impact timelines or cost. Lead discussions with functional leads to develop solutions and propose mitigation strategies to the executive team. • Collaborate with functional leadership to assign best-aligned SME for project needs and set clear goals/objectives for each project team member. • Lead and coach teams to break down silos, encourage collaboration, and ensure the program strategy aligns with broader company initiatives. • Create presentations, memos, and dashboards to communicate program status to general, technical, or executive audiences. About you: • Bachelor's degree required with a specialization in science, engineering, or health related field; advanced degree is a plus not required. PMP, or other project management certification is a plus but not required. • 10+ yrs of experience in the pharmaceutical industry or life science field. • Knowledgeable in discovery, preclinical development, clinical trial activities, CMC & commercialization. • Enjoy thinking creatively, anticipating challenges, and developing innovative solutions to complex problems. • Effective, concise verbal and written communication style, from general to executive audiences. • Highly collaborative individual who fosters open communication and possesses strong interpersonal skills. • Ability to take initiative and execute on time-sensitive needs. • Enjoys & has a successful track record in coaching/mentoring new PMs. Salary range: $200,000 - $240,000 Loyal benefits: • Full-coverage health insurance — medical, dental and vision — for you and your dependents • $1,000 home office equipment stipend • $1,200/year learning budget for books, courses, etc. • $250/month wellness budget for gym, cleaners, spa, food, etc. • All 3-day weekends are turned into 4-day weekends 🎉 • Unlimited vacation and paid holidays • Paw-ternity leave — adopt a dog and get a day off with your new family member 🐶 • Competitive salary • Company equity options grant for new hires Loyal is founded and led by a first-gen female CEO and is proud to be an equal opportunity employer. We do not discriminate against applicants based on gender, race or color, ethnicity or national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, or any other applicable characteristics protected by law. Our values Lean into moonshots We don't settle for incremental change. We have the bravery to take risks and shoot for the impact we want to have. Opportunity is at the intersection We lean into combining disciplines, expertises, and perspectives not normally adjacent. We design our organization to facilitate cross-pollination and cross-collaboration. We reject silos. Expertise without ego Titles do not determine who has a voice. We work on hard technical problems and have a ton of fun while at it. Learning by doing Our path is novel and many things we are doing have never been done before. We lean into MVPs and are open to unexpected outcomes. Lead with context We value leading with context. We equip people with the context and background necessary to make their own decisions and act in the best interest of Loyal. We empower teams to succeed. Empathy and respect for all life Our patients are not just numbers. Our work is intentional, thoughtful, and guided by respect for life. We take our responsibility to pets and pet parents seriously.

Lead veterinary marketing and education strategies to drive awareness and adoption of veterinary longevity drugs, manage a small team, and build partnerships within the veterinary community. | 8+ years in marketing or clinical education within animal health or related life sciences, proven success in veterinary community engagement, digital marketing expertise, leadership experience, and willingness to travel. | About Loyal Loyal is a clinical-stage veterinary medicine company developing drugs intended to extend the lifespan and healthspan of dogs. Our mission is to help dogs live longer, healthier lives. We’ve already achieved significant milestones on our path to earning FDA approval for the first lifespan extension drug for any species. We have three products in our pipeline and are on track for FDA conditional approval within the next year. Loyal is a well-funded startup in growth mode. Our team includes scientists, veterinarians, engineers, operators, and creatives. This role will play a key role in supporting our growth strategies. About the role We’re seeking an experienced Head of Veterinary Marketing to lead our efforts to drive awareness, education, and adoption of LOY-002 and future pipeline drugs within the veterinary community. This leader will be responsible for equipping veterinary professionals with the knowledge and confidence they need to embrace longevity medicine and to prescribe our products. This role sits at the intersection of science, education, and marketing. You will own our veterinary marketing funnel from top to bottom. You will partner with our clinical team of veterinarians to develop and execute strategies that educate the veterinary community about aging as a modifiable risk factor for nearly all diseases that shorten dog lifespan, the anticipated clinical benefit of our product(s), safety, and the benefits of early adoption. You will develop content and strategies to nurture interest leading up to launch, as well as developing and executing our veterinary marketing plan for launch. You will be a key partner to our business development and sales teams, building the education-first foundation that ultimately converts early awareness into prescribing behavior. You will manage and grow a small but high-impact team responsible for veterinary continuing education content and strategy in partnership with our clinical team, events and conferences, and partnerships with key opinion leaders, influencers, and other industry groups. The successful candidate should be an excellent operator who can create structure and clarity out of ambiguity, and get things done quickly and excellently in a startup environment. You will be reporting to our Chief Commercial Officer. Key Responsibilities Be the voice of the veterinary industry in all things veterinary consumer-driven and commercial strategy Develop and execute a bespoke, veterinary education strategy to raise awareness of longevity medicine and LOY-002, in partnership with our clinical team Partner with clinical team to design and oversee CE programs (digital and live), ensuring content is scientifically rigorous, accessible, and engaging to the particular audience Lead Loyal’s presence and CE initiatives at veterinary conferences, maximizing educational impact and brand visibility Build and manage partnerships with veterinary associations, schools, and thought leaders to amplify Loyal’s message and build credibility in the field ahead of launch Design education pathways that nurture early adopters and move them toward prescribing Drive the development of digital content and campaigns that extend reach and engagement beyond live events Manage and mentor the veterinary marketing team, ensuring alignment with broader goals Establish clear metrics for awareness, education engagement, and conversion, and report progress regularly to the leadership team Ensure all aspects of veterinary communication are compliant with regulatory guidance About You Veterinary industry expertise: You bring proven experience in animal health, veterinary education, or related fields, with a deep understanding of how to engage and influence the veterinary community Education-first marketer: You are passionate about educating professionals and building trust in new categories through clear, science-driven storytelling Digital fluency: You understand how to leverage modern digital marketing tools and platforms to scale education and engagement Builder mindset: You thrive in early-stage environments, are comfortable creating strategy and process from scratch, and are motivated by the opportunity to launch a new category Leadership: You have experience managing and growing small teams and are skilled at balancing high-level strategy with hands-on execution Collaborative spirit: You work cross-functionally with scientists, clinicians, product teams, and other commercial leaders, and excel at building relationships with external partners Qualifications 8+ years of marketing, clinical education or communications experience within the animal health, pharmaceutical, or life sciences sectors; animal health strongly preferred Demonstrated success driving awareness and education initiatives within the veterinary community Experience with digital marketing platforms, audience segmentation, and driving marketing-qualified leads Excellent communication, presentation, and story-telling skills Willingness to travel to conferences, events, and partner sites as needed Salary Range: $ Loyal Benefits: Full-coverage health insurance — medical, dental and vision — for you and your dependents $1,000 home office equipment stipend $1,200/year learning budget for books, courses, etc. $250/month wellness budget for gym, cleaners, spa, food, etc. All 3-day weekends are turned into 4-day weekends 🎉 Unlimited vacation and paid holidays Paw-ternity leave — adopt a dog and get a day off with your new family member 🐶 Annual company retreat at beautiful locations across the country (recently: Tahoe, Cape Cod) Competitive salary Company equity options grant for new hires Salary range: $180,000 - $220,000 Loyal is founded and led by a first-gen, female CEO and is proud to be an equal opportunity employer. We do not discriminate against applicants based on gender, race or color, ethnicity or national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, or any other applicable characteristics protected by law. Our Values Lean into moonshots | We do not settle for incremental change. We have the bravery to take risks and shoot for the impact we want to have. Opportunity is at the intersection | We lean into combining disciplines, expertises, and perspectives not normally adjacent. We design our organization to facilitate cross-pollination and cross-collaboration. We reject silos. Expertise without ego | Titles do not determine who has a voice. We work on hard, technical problems and have a ton of fun while at it. Learning by doing | Our path is novel and many things we are doing have never been done before. We lean into MVPs and are open to unexpected outcomes. Lead with context | We equip people with the context and background necessary to make their own decisions and act in the best interest of Loyal. We empower teams to succeed. Empathy and respect for all life | Our patients are not just numbers. Our work is intentional, thoughtful, and guided by respect for life. We take our responsibility to pets and pet parents seriously.