Loyal

Lead and integrate technical CMC operations from early development through commercialization, ensuring scientific rigor, risk management, and manufacturing readiness for drug products. | PhD in Chemical Engineering or related field, 12+ years in biopharmaceutical CMC development with leadership in early-stage development through product launch, expertise in small molecules and oral solid dosage, and regulatory knowledge. | About Loyal Loyal is a clinical-stage veterinary medicine company developing drugs intended to extend the lifespan and healthspan of dogs. Our mission is to help dogs live longer, healthier lives. We’ve already achieved significant milestones on our path to earning FDA approval for the first lifespan extension drug for any species. We have three products in our pipeline and are on track for FDA conditional approval within the next year. Loyal is a well-funded startup in growth mode. Our team includes scientists, veterinarians, engineers, operators, and creatives. This role will play a key role in supporting our growth strategies. About the role We’re seeking an experienced Senior Director, Technical Operations to provide technical leadership across all CMC disciplines as we advance our programs from early development through commercialization — including preparations for upcoming product launch. This role serves as a cornerstone of our Technical Operations organization, ensuring connectivity, scientific rigor, and technical excellence across process, analytical, and formulation development, manufacturing, and supply. The ideal candidate holds a PhD in Chemical Engineering or a related discipline, brings deep expertise in small molecule and oral solid dosage development, has led early-stage CMC activities, and possesses a proven track record of launching commercial products. You’ll integrate and drive the technical aspects of CMC strategy — ensuring robust science, risk-based decision-making, and manufacturing readiness that support Loyal’s mission and future launches. This role reports to the Chief Technical Operations Officer and works closely with CMC functional leads and executive leadership. This role reports to the Chief Technical Operations Officer. Your daily work will include Provide technical leadership and integration across process, analytical, and formulation development, ensuring scientific rigor, data integrity, and seamless progression from early development through commercialization. Drive technical connectivity among CMC functions to maintain alignment, consistency, and robust science across all development stages. Lead technical risk assessment, mitigation, and decision-making, ensuring issues are identified, analyzed, and resolved through data-driven approaches. Partner with CMC functional leads and CDMOs to develop and refine scalable, robust, and reproducible processes for drug substance and oral solid dosage drug and finished products. Oversee technical readiness for key milestones including IND/IMPD, NDA/MAA, and commercial launch. Lead or contribute to CMC sections of regulatory submissions and represent Loyal in technical discussions with regulatory authorities. Collaborate closely with Quality, Regulatory, Clinical, and Commercial functions to ensure technical and operational alignment. Mentor and guide internal scientists and external partners to uphold a culture of technical excellence and accountability. About you PhD in Chemical Engineering or a closely related discipline, or equivalent industrial experience with deep technical expertise in process, analytical, and formulation development. 12+ years of experience in biopharmaceutical CMC development and manufacturing, with increasing technical leadership responsibilities. Proven experience leading early CMC development through successful product launch, including process validation and technology transfer. Experience with small molecules and oral solid dosage forms strongly preferred. Strong understanding of process and formulation design, scale-up, and control for both drug substance and drug product. Demonstrated success guiding CDMOs and cross-functional CMC teams through complex technical challenges. Comprehensive knowledge of global CMC regulatory expectations (FDA, EMA, ICH) and ability to translate technical findings into regulatory strategies. Excellent technical judgment with the ability to synthesize complex data into clear, sound decisions. Collaborative, pragmatic, and thrives in a fast-paced, matrixed, mission-driven biotech environment. Nice to have Experience building or scaling Technical Operations capabilities during the transition from development to commercialization. Familiarity with lifecycle management, continued process verification, and commercial supply optimization. Experience with veterinary or animal health manufacturing. Passion for Loyal’s mission to bring science-driven longevity therapeutics to dogs — and ultimately humans. Salary range: $230,000 - $280,000 Loyal benefits Full-coverage health insurance — medical, dental and vision — for you and your dependents $1,000 home office equipment stipend $1,200/year learning budget for books, courses, etc. $250/month wellness budget for gym, cleaners, spa, food, etc. All 3-day weekends are turned into 4-day weekends 🎉 Unlimited vacation and paid holidays Paw-ternity leave — adopt a dog and get a day off with your new family member 🐶 Competitive salary Company equity options grant for new hires Loyal is founded and led by a first-gen female CEO and is proud to be an equal opportunity employer. We do not discriminate against applicants based on gender, race or color, ethnicity or national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, or any other applicable characteristics protected by law. Our values Lean into moonshots We don’t settle for incremental change. We have the bravery to take risks and shoot for the impact we want to have. Opportunity is at the intersection We lean into combining disciplines, expertises, and perspectives not normally adjacent. We design our organization to facilitate cross-pollination and cross-collaboration. We reject silos. Expertise without ego Titles do not determine who has a voice. We work on hard technical problems and have a ton of fun while at it. Learning by doing Our path is novel and many things we are doing have never been done before. We lean into MVPs and are open to unexpected outcomes. Lead with context We value leading with context. We equip people with the context and background necessary to make their own decisions and act in the best interest of Loyal. We empower teams to succeed. Empathy and respect for all life Our patients are not just numbers. Our work is intentional, thoughtful, and guided by respect for life. We take our responsibility to pets and pet parents seriously.

Lead program management activities to drive FDA approval timelines, coordinate cross-functional teams, manage risks and escalations, and communicate status to executives. | 10+ years pharmaceutical or life science experience, bachelor's degree in science/engineering/health, strong program management skills, and ability to lead and coach teams. | About Loyal Loyal is a clinical-stage veterinary medicine company developing drugs intended to extend the lifespan and healthspan of dogs. Our mission is to help dogs live longer, healthier lives. We've already achieved significant milestones on our path to earning FDA approval for the first lifespan extension drug for any species. We have three products in our pipeline and are on track for FDA conditional approval within the next year. Loyal is a well-funded startup in growth mode. Our team includes scientists, veterinarians, engineers, operators, and creatives. This role will play a key role in supporting our growth strategies. About The Role The Senior Director, Program Manager will play a pivotal role in bringing one of our longevity drug pipelines through FDA approval and expanding Loyal's portfolio. You will be the go-to point of contact for all program-related activities, lead the program team in formulating strategies that align with corporate goals, and lead efforts in building and scaling the program management/project management infrastructure. You will work closely with the senior executive team. This role is for someone looking to leverage their knowledge of program management to help transform Loyal into a commercial enterprise. The ideal candidate is a highly collaborative team player and requires strategic leadership, strong interpersonal and communication skills, and a willingness to learn multiple disciplines. You will report to our Chief R&D Officer. Your daily work will include: • Serve as the program spokesperson. • Own program timeline, understand dependencies, and ensure alignment with regulatory requirements. • Lead cross-functional discussions to ensure timely and proactive discussions around risks, status, opportunities, and mitigation/acceleration strategies. • Work closely with functional leads to ensure team projects are completed on time, within budget, and maintain quality standards. • Escalate program issues that can impact timelines or cost. Lead discussions with functional leads to develop solutions and propose mitigation strategies to the executive team. • Collaborate with functional leadership to assign best-aligned SME for project needs and set clear goals/objectives for each project team member. • Lead and coach teams to break down silos, encourage collaboration, and ensure the program strategy aligns with broader company initiatives. • Create presentations, memos, and dashboards to communicate program status to general, technical, or executive audiences. About you: • Bachelor's degree required with a specialization in science, engineering, or health related field; advanced degree is a plus not required. PMP, or other project management certification is a plus but not required. • 10+ yrs of experience in the pharmaceutical industry or life science field. • Knowledgeable in discovery, preclinical development, clinical trial activities, CMC & commercialization. • Enjoy thinking creatively, anticipating challenges, and developing innovative solutions to complex problems. • Effective, concise verbal and written communication style, from general to executive audiences. • Highly collaborative individual who fosters open communication and possesses strong interpersonal skills. • Ability to take initiative and execute on time-sensitive needs. • Enjoys & has a successful track record in coaching/mentoring new PMs. Salary range: $200,000 - $240,000 Loyal benefits: • Full-coverage health insurance — medical, dental and vision — for you and your dependents • $1,000 home office equipment stipend • $1,200/year learning budget for books, courses, etc. • $250/month wellness budget for gym, cleaners, spa, food, etc. • All 3-day weekends are turned into 4-day weekends 🎉 • Unlimited vacation and paid holidays • Paw-ternity leave — adopt a dog and get a day off with your new family member 🐶 • Competitive salary • Company equity options grant for new hires Loyal is founded and led by a first-gen female CEO and is proud to be an equal opportunity employer. We do not discriminate against applicants based on gender, race or color, ethnicity or national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, or any other applicable characteristics protected by law. Our values Lean into moonshots We don't settle for incremental change. We have the bravery to take risks and shoot for the impact we want to have. Opportunity is at the intersection We lean into combining disciplines, expertises, and perspectives not normally adjacent. We design our organization to facilitate cross-pollination and cross-collaboration. We reject silos. Expertise without ego Titles do not determine who has a voice. We work on hard technical problems and have a ton of fun while at it. Learning by doing Our path is novel and many things we are doing have never been done before. We lean into MVPs and are open to unexpected outcomes. Lead with context We value leading with context. We equip people with the context and background necessary to make their own decisions and act in the best interest of Loyal. We empower teams to succeed. Empathy and respect for all life Our patients are not just numbers. Our work is intentional, thoughtful, and guided by respect for life. We take our responsibility to pets and pet parents seriously.

Lead veterinary marketing and education strategies to drive awareness and adoption of veterinary longevity drugs, manage a small team, and build partnerships within the veterinary community. | 8+ years in marketing or clinical education within animal health or related life sciences, proven success in veterinary community engagement, digital marketing expertise, leadership experience, and willingness to travel. | About Loyal Loyal is a clinical-stage veterinary medicine company developing drugs intended to extend the lifespan and healthspan of dogs. Our mission is to help dogs live longer, healthier lives. We’ve already achieved significant milestones on our path to earning FDA approval for the first lifespan extension drug for any species. We have three products in our pipeline and are on track for FDA conditional approval within the next year. Loyal is a well-funded startup in growth mode. Our team includes scientists, veterinarians, engineers, operators, and creatives. This role will play a key role in supporting our growth strategies. About the role We’re seeking an experienced Head of Veterinary Marketing to lead our efforts to drive awareness, education, and adoption of LOY-002 and future pipeline drugs within the veterinary community. This leader will be responsible for equipping veterinary professionals with the knowledge and confidence they need to embrace longevity medicine and to prescribe our products. This role sits at the intersection of science, education, and marketing. You will own our veterinary marketing funnel from top to bottom. You will partner with our clinical team of veterinarians to develop and execute strategies that educate the veterinary community about aging as a modifiable risk factor for nearly all diseases that shorten dog lifespan, the anticipated clinical benefit of our product(s), safety, and the benefits of early adoption. You will develop content and strategies to nurture interest leading up to launch, as well as developing and executing our veterinary marketing plan for launch. You will be a key partner to our business development and sales teams, building the education-first foundation that ultimately converts early awareness into prescribing behavior. You will manage and grow a small but high-impact team responsible for veterinary continuing education content and strategy in partnership with our clinical team, events and conferences, and partnerships with key opinion leaders, influencers, and other industry groups. The successful candidate should be an excellent operator who can create structure and clarity out of ambiguity, and get things done quickly and excellently in a startup environment. You will be reporting to our Chief Commercial Officer. Key Responsibilities Be the voice of the veterinary industry in all things veterinary consumer-driven and commercial strategy Develop and execute a bespoke, veterinary education strategy to raise awareness of longevity medicine and LOY-002, in partnership with our clinical team Partner with clinical team to design and oversee CE programs (digital and live), ensuring content is scientifically rigorous, accessible, and engaging to the particular audience Lead Loyal’s presence and CE initiatives at veterinary conferences, maximizing educational impact and brand visibility Build and manage partnerships with veterinary associations, schools, and thought leaders to amplify Loyal’s message and build credibility in the field ahead of launch Design education pathways that nurture early adopters and move them toward prescribing Drive the development of digital content and campaigns that extend reach and engagement beyond live events Manage and mentor the veterinary marketing team, ensuring alignment with broader goals Establish clear metrics for awareness, education engagement, and conversion, and report progress regularly to the leadership team Ensure all aspects of veterinary communication are compliant with regulatory guidance About You Veterinary industry expertise: You bring proven experience in animal health, veterinary education, or related fields, with a deep understanding of how to engage and influence the veterinary community Education-first marketer: You are passionate about educating professionals and building trust in new categories through clear, science-driven storytelling Digital fluency: You understand how to leverage modern digital marketing tools and platforms to scale education and engagement Builder mindset: You thrive in early-stage environments, are comfortable creating strategy and process from scratch, and are motivated by the opportunity to launch a new category Leadership: You have experience managing and growing small teams and are skilled at balancing high-level strategy with hands-on execution Collaborative spirit: You work cross-functionally with scientists, clinicians, product teams, and other commercial leaders, and excel at building relationships with external partners Qualifications 8+ years of marketing, clinical education or communications experience within the animal health, pharmaceutical, or life sciences sectors; animal health strongly preferred Demonstrated success driving awareness and education initiatives within the veterinary community Experience with digital marketing platforms, audience segmentation, and driving marketing-qualified leads Excellent communication, presentation, and story-telling skills Willingness to travel to conferences, events, and partner sites as needed Salary Range: $ Loyal Benefits: Full-coverage health insurance — medical, dental and vision — for you and your dependents $1,000 home office equipment stipend $1,200/year learning budget for books, courses, etc. $250/month wellness budget for gym, cleaners, spa, food, etc. All 3-day weekends are turned into 4-day weekends 🎉 Unlimited vacation and paid holidays Paw-ternity leave — adopt a dog and get a day off with your new family member 🐶 Annual company retreat at beautiful locations across the country (recently: Tahoe, Cape Cod) Competitive salary Company equity options grant for new hires Salary range: $180,000 - $220,000 Loyal is founded and led by a first-gen, female CEO and is proud to be an equal opportunity employer. We do not discriminate against applicants based on gender, race or color, ethnicity or national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, or any other applicable characteristics protected by law. Our Values Lean into moonshots | We do not settle for incremental change. We have the bravery to take risks and shoot for the impact we want to have. Opportunity is at the intersection | We lean into combining disciplines, expertises, and perspectives not normally adjacent. We design our organization to facilitate cross-pollination and cross-collaboration. We reject silos. Expertise without ego | Titles do not determine who has a voice. We work on hard, technical problems and have a ton of fun while at it. Learning by doing | Our path is novel and many things we are doing have never been done before. We lean into MVPs and are open to unexpected outcomes. Lead with context | We equip people with the context and background necessary to make their own decisions and act in the best interest of Loyal. We empower teams to succeed. Empathy and respect for all life | Our patients are not just numbers. Our work is intentional, thoughtful, and guided by respect for life. We take our responsibility to pets and pet parents seriously.