Day One Biopharmaceuticals

Oversee daily office operations, manage vendor relationships, and coordinate employee engagement activities. | Requires 3-5 years in facilities or workplace operations, experience with safety programs, and event coordination, which are not reflected in your profile. | FACILITIES & WORKPLACE OPERATIONS MANAGER At Day One, we are focused on advancing first- or best-in-class medicines for childhood and adult diseases with equal intensity. We were founded to address the lack of new therapies resulting from the traditional drug development model, that has left children with cancer and their families waiting too long for new, life-changing treatments. Our aim is to accelerate better, targeted treatments so patients of any age can look forward from ‘day one’ to the future they’ve envisioned. POSITION SUMMARY: We are seeking a proactive and highly organized Facilities & Workplace Operations Manager to oversee the day-to-day operations of our Brisbane office. This role is critical to ensuring our teams have a welcoming, efficient, and engaging workplace that supports productivity while building community and connection that reflects our company culture. The ideal candidate brings strong operational experience with a creative spirit to host fun and engaging corporate events, and a passion for creating seamless employee experiences – beginning from their first day onboarding to company-wide events to daily office operations. Reports to Senior Director, People Operations. This role is based in the Brisbane Office and candidates must be able to commute to the Brisbane office with regular in-office days to support the day-to-day operations in the office and ad-hoc in-office events and activities. ESSENTIAL DUTIES AND RESPONSIBILITIES: Facilities & Workplace Operations Oversee day-to-day office management, including lunch and snack programs, office supplies, mail and packages, equipment, kitchen, storage and shared spaces to ensure a safe, functional and well-organized work environment Manage relationships with building management, maintenance and external vendors to coordinate office maintenance, repairs, space planning and workplace improvement requests Support office moves, expansions, seating plans and workspace optimization Establish office operational and best practices procedures, and manage related communications Oversee and manage facilities budgets, including related facilities contracts and service agreements with external vendors Develop process efficiency and scalability as business needs evolve Workplace Safety & Compliance Lead workplace safety programs, including annual Safety Month, safety and emergency preparedness, safety protocols, emergency evacuation procedures, and ergonomic assessments Conduct periodic safety reviews to ensure compliance with workplace safety programs and guidelines Maintain documentation required for safety programs and building compliance Employee Experience & Culture Plan and execute virtual, onsite and offsite corporate events, including social and learning events, All Hands, celebrations and other employee engagement activities Manage event logistics, including catering, AV, space setup, vendor coordination and budget management Partner with key stakeholders on culture-building initiatives, swag programs, employee experience and recognition programs to foster connection and engagement to support our remote hybrid work model Partner with cross-functional stakeholders to facilitate seamless new hire onboarding experiences Partner with Corporate Communications to develop and maintain relevant employee communications related to policy rollouts and other internal programs Provide support for other People Team programs and initiatives, as needed QUALIFICATIONS Bachelor’s degree, or equivalent work experience 3-5 years of experience in facilities management, workplace operations, office management and/or a related field Familiarity with workplace safety programs, compliance regulations, and emergency response planning Demonstrated experience in coordinating corporate events, workplace activities and culture building initiatives Experience with supporting onboarding and other employee lifecycle processes Strong project planning experience to drive project deliverables and execution Strong organizational and problem-solving skills with ability to manage multiple priorities simultaneously Strong leadership, communication and interpersonal skills to partner with people at all levels to drive decision making, effective partnership and execution Proactive and resourceful with a strong ownership and accountability mindset Ability to adapt to changing priorities and evolving business needs while maintaining consistency and work quality Proficiency with office technologies, workplace and project management tools Experience in Biotech preferred The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. INTERVIEW INTEGRITY At Day One, we expect each candidate to engage authentically, representing their true qualifications and experiences. As part of our screening process, we will conduct several interviews and background verification. This ensures candidates have the skills they claim and align with our values. We are excited to learn more about you and to create a genuine experience for everyone. COMPENSATION AND BENEFITS The salary range for this position is $128,000 - $140,000. Day One considers a range of factors when determining base compensation. These considerations mean actual compensation will vary. Please visit https://www.dayonebio.com/benefits to see our competitive benefits. DISCLAIMER Day One Biopharmaceuticals is committed to providing an environment of mutual respect where equal employment opportunities are available to all applicants without regard to race, color, religion, sex, pregnancy (including childbirth and related medical conditions), national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information (including characteristics and testing), military and veteran status, and any other characteristic protected by applicable law. We are unable to sponsor or take over sponsorship of any applicant work visas at this time. Recruitment & Staffing Agencies: Day One Biopharmaceuticals does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Day One Biopharmaceuticals or its employees is strictly prohibited unless contacted directly by Day One Biopharmaceutical’s internal HR team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Day One Biopharmaceuticals, and Day One Biopharmaceuticals will not owe any referral or other fees with respect thereto.

Designing and enabling systems, frameworks, and leadership behaviors to improve organizational effectiveness and decision-making. | Over 10 years of experience in organizational development or enterprise leadership, with strong facilitation skills and systems thinking. | DIRECTOR, ORGANIZATIONAL DEVELOPMENT At Day One, we are focused on advancing first- or best-in-class medicines for childhood and adult diseases with equal intensity. We were founded to address the lack of new therapies resulting from the traditional drug development model, that has left children with cancer and their families waiting too long for new, life-changing treatments. Our aim is to accelerate better, targeted treatments so patients of any age can look forward from ‘day one’ to the future they’ve envisioned. POSITION SUMMARY: Reporting to the VP, People Business Partners, you will work across all levels of the organization, from executives, functional leaders, product teams, to intact teams, helping leaders move from functional excellence to enterprise effectiveness. You are a builder, a facilitator, and a quiet force for clarity. Strong preference for candidates in San Francisco Bay Area or Greater Boston area who can work a hybrid schedule with regular in-office days. The Opportunity The Director of Organizational Development is an enterprise capability builder. This role designs and enables the systems, frameworks, and leadership behaviors that allow Day One to operate as a cohesive, decision-capable organization, especially as complexity increases across functions, product teams, and stages of development. This is not a traditional training role. There are no standard curricula to manage and no classrooms to run. Instead, this role focuses on: Strengthening enterprise mindset Improving decision quality and speed Enabling effective cross-functional leadership Supporting the evolution of product team–centric ways of working We are building a company designed for decisions that matter: scientific, clinical, and commercial choices made with rigor, speed, and shared accountability. As we scale, success depends not just on what we decide—but how we decide, together. This role exists to help make that “how” intentional. ESSENTIAL DUTIES AND RESPONSIBILITIES: How This Role Fits This role is intentionally complementary to the HR Business Partner role. The HRBP partners deeply with leaders on people strategy, talent, rewards, and leadership decisions. The Director of Organizational Development builds the operating system that helps those leaders and teams think, decide, and work together effectively. You will collaborate closely, frequently, and with mutual respect, with each role distinct, synergistic, and essential. What You Will Do Enterprise Capability & Decision-Making Design and implement decision-making frameworks that improve clarity, accountability, and speed across the enterprise. Help leaders navigate complex trade-offs by introducing shared language, decision rights, and escalation paths. Enable enterprise-level thinking to help leaders optimize for Day One, not just their function or team. Organizational Effectiveness & Ways of Working Build and evolve operating models that support cross-functional collaboration (e.g Product teams, sub-teams, MLR, etc). Partner with teams to clarify roles, interfaces, and expectations as the organization scales. Diagnose organizational friction points and facilitate practical, human-centered interventions. Leadership & Culture Enablement Translate Day One’s values and leadership expectations into observable behaviors and practices. Design leadership tools, playbooks, and forums that reinforce enterprise mindset and accountability. Support leaders through moments of growth, change, and ambiguity with grounded, thoughtful guidance. Product Team Enablement (Supportive, Not Owning) Serve as a strategic resource to product teams and leaders operating within the product team primacy model. Support the development of team charters, decision forums, and collaboration norms. Help leaders reflect on and enhance how product teams function without taking ownership of or policing execution. Facilitation & Strategic Intervention Facilitate leadership sessions, team resets, and cross-functional working sessions when alignment or clarity is needed. Use data, observation, and listening to inform recommendations and next steps. Balance structure with flexibility, knowing when to guide, when to challenge, and when to get out of the way! What Success Looks Like Within the first 12–18 months: Leaders make faster, clearer decisions with less rework and less organizational swirl. Teams operate with stronger enterprise mindset, prioritizing shared outcomes over local optimization. Cross-functional collaboration feels more intentional, less heroic. Product teams and leaders have practical tools to support how they work, not just more processes for the sake of process. The organization feels more aligned as it scales, without losing momentum or humanity. QUALIFICATIONS Who You Are You are thoughtful, grounded, and pragmatic. You bring: 10+ years of experience in organizational development, organizational effectiveness, or enterprise leadership enablement—ideally within biotech, pharma, healthcare, or complex matrixed environments. Demonstrated success building enterprise capabilities, not just programs. Strong facilitation skills and comfort working with senior leaders and intact teams. Systems thinking: you see patterns, incentives, and unintended consequences. Sound judgment and emotional intelligence; you know when to push and when to pause. Comfort operating through influence in a matrix, flexing style based on context and audience. What you are not: A traditional trainer A policy enforcer An empire builder You are here to make the organization better at doing the work that matters most. How We Work at Day One At Day One, how we show up matters. Patients first: decisions grounded in purpose and impact. Candor with care: honest conversations delivered with respect. Collaboration over hierarchy: progress through partnership. Inclusion and belonging: where diverse perspectives strengthen outcomes. Ownership: we do what we say we will do. You don’t need to be perfect. You do need to be thoughtful, accountable, and human. We take the mission seriously—and ourselves lightly. A well-placed metaphor is welcome if it helps people see more clearly. Why This Role Matters This is a rare opportunity to help shape how a growing biotech thinks, decides, and works—at a moment when those capabilities will determine long-term success. If you are energized by complexity, partnership, and building something durable (without needing the spotlight), this role may feel like home. The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. INTERVIEW INTEGRITY At Day One, we expect each candidate to engage authentically, representing their true qualifications and experiences. As part of our screening process, we will conduct several interviews and background verification. This ensures candidates have the skills they claim and align with our values. We are excited to learn more about you and to create a genuine experience for everyone. COMPENSATION AND BENEFITS The salary range for this position is $215,000 - $230,000. Day One considers a range of factors when determining base compensation. These considerations mean actual compensation will vary. Please visit https://www.dayonebio.com/benefits to see our competitive benefits. DISCLAIMER Day One Biopharmaceuticals is committed to providing an environment of mutual respect where equal employment opportunities are available to all applicants without regard to race, color, religion, sex, pregnancy (including childbirth and related medical conditions), national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information (including characteristics and testing), military and veteran status, and any other characteristic protected by applicable law. We are unable to sponsor or take over sponsorship of any applicant work visas at this time. Recruitment & Staffing Agencies: Day One Biopharmaceuticals does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Day One Biopharmaceuticals or its employees is strictly prohibited unless contacted directly by Day One Biopharmaceutical’s internal HR team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Day One Biopharmaceuticals, and Day One Biopharmaceuticals will not owe any referral or other fees with respect thereto.

Serve as a senior HR advisor to R&D leadership, shaping organizational strategy, culture, and internal communications, while embedding inclusion and belonging. | 15+ years of senior HR leadership experience, deep expertise in total rewards and compensation, and experience partnering with scientific or biotech organizations at the executive level. | SENIOR DIRECTOR, STRATEGIC PEOPLE BUSINESS PARTNER At Day One, we are focused on advancing first- or best-in-class medicines for childhood and adult diseases with equal intensity. We were founded to address the lack of new therapies resulting from the traditional drug development model, that has left children with cancer and their families waiting too long for new, life-changing treatments. Our aim is to accelerate better, targeted treatments so patients of any age can look forward from ‘day one’ to the future they’ve envisioned. POSITION SUMMARY: This is a strategic, enterprise-level HR leadership role for an experienced executive who wants to be deeply embedded in the business, influencing decisions, shaping leaders, and building durable people systems, without the administrative drag or title inflation that often comes with senior HR roles. As the primary HR Business Partner to Research & Development, you will work directly with the Head of R&D and their leadership team, serving as a trusted advisor on organizational strategy, leadership effectiveness, talent, and culture. You will also play a critical enterprise role in shaping internal communications and total compensation strategy, two capabilities essential to Day One’s next phase of growth. This role reports to the VP, People Business Partners. This role is intentionally scoped for impact, influence, and trust, not empire-building. Strong preference for candidates in the Greater Boston area who can work a hybrid schedule with regular in-office days. ESSENTIAL DUTIES AND RESPONSIBILITIES: Strategic HR Partnership – R&D Serve as the senior HR advisor to the Head of R&D and his leadership team, partnering on strategy, org design, workforce planning, leadership development, and succession. Translate scientific and portfolio strategy into people and organizational plans that scale with rigor and flexibility. Coach senior leaders through complex decisions of growth, change, performance, and culture, grounded in sound judgment and business context. Act as a connective tissue between R&D and the broader enterprise, ensuring alignment without slowing momentum. Enterprise Internal Communications Partner closely with the Chief People Officer to design and mature a robust internal communications capability appropriate for a growing public biotech. Advise executives on clear, authentic communication during moments of change, growth, and ambiguity. Help leaders in crafting a clear story about the direction of Day One and how each employee plays a role in the mission. Culture, Values & Inclusion Serve as a visible steward of Day One’s culture and leadership expectations. Embed inclusion and belonging into talent, rewards, leadership behaviors, and decision-making—not as a program, but as a way of working. Model executive-level partnership grounded in trust, discretion, and accountability. QUALIFICATIONS 15+ years of senior HR leadership experience, ideally within Biotech, TechBio, or Healthcare. Sound judgment, emotional intelligence, and comfort navigating ambiguity. Demonstrated success partnering with R&D or scientific organizations at the executive level. Deep expertise in total rewards and compensation strategy, especially pay for performance, goal setting, and team performance. Strong business and financial acumen: you understand how people strategy enables pipeline execution and enterprise value. Executive presence paired with humility: you influence through credibility, not volume. A builder’s mindset: you enjoy creating structure, clarity, and trust where they matter most. How We Work at Day One At Day One, how we show up matters. Audacious Outcomes: We do what we say we will do. Urgency with Purpose: Decisions grounded in purpose and impact. Building Bridges, Not Silos: Progress through partnership. Inclusion and belonging: Where diverse perspectives strengthen outcomes and honest conversations are delivered with respect. You don’t need to be perfect. You do need to be thoughtful, accountable, and human. We take the mission seriously and ourselves lightly. A well-placed metaphor is welcome if it helps people see more clearly. Why This Role Is Different Direct partnership with R&D leadership at a critical inflection point Broad enterprise scope with real ownership (not advisory-only) Opportunity to shape culture, rewards, and leadership in a growing public biotech A chance to apply deep expertise where it truly matters—without unnecessary layers The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. INTERVIEW INTEGRITY At Day One, we expect each candidate to engage authentically, representing their true qualifications and experiences. As part of our screening process, we will conduct several interviews and background verification. This ensures candidates have the skills they claim and align with our values. We are excited to learn more about you and to create a genuine experience for everyone. COMPENSATION AND BENEFITS The salary range for this position is $260,000 - $280,000. Day One considers a range of factors when determining base compensation. These considerations mean actual compensation will vary. Please visit https://www.dayonebio.com/benefits to see our competitive benefits. DISCLAIMER Day One Biopharmaceuticals is committed to providing an environment of mutual respect where equal employment opportunities are available to all applicants without regard to race, color, religion, sex, pregnancy (including childbirth and related medical conditions), national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information (including characteristics and testing), military and veteran status, and any other characteristic protected by applicable law. We are unable to sponsor or take over sponsorship of any applicant work visas at this time. Recruitment & Staffing Agencies: Day One Biopharmaceuticals does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Day One Biopharmaceuticals or its employees is strictly prohibited unless contacted directly by Day One Biopharmaceutical’s internal HR team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Day One Biopharmaceuticals, and Day One Biopharmaceuticals will not owe any referral or other fees with respect thereto.