BeiGene

Provide legal support for global R&D activities, including regulatory, contractual, and risk management, while leading and mentoring a legal team. | 15+ years in legal roles with a focus on biotech/pharma, in-house experience, deep knowledge of R&D legal landscape, and leadership skills. | BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. General Description: BeOne Medicines is seeking a highly experienced R&D attorney with deep experience to provide comprehensive legal support for the global R&D function. As a key member of both the Legal and R&D leadership teams, you will play a pivotal role in navigating the complex legal landscape associated with research and development in the biotech sector. This role will be a critical addition to the company, providing legal guidance, regulatory support, and risk management expertise to propel our oncology and inflammation & immunology research and development programs forward. The ideal candidate will possess a deep understanding of biotech and pharmaceutical law, intellectual property, and regulatory compliance, particularly as it pertains to R&D. As the Leader of the R&D Legal function this role will support all facets of R&D including Regulatory, Research, Development, Clinical Operations, Safety and Pharmacology. Position is a remote role based in the US. Essential Functions of the Job: • Provide comprehensive legal support to the global R&D function, ensuring effective risk management and compliance with applicable laws and regulations. • Partner with R&D leaders to shape and implement strategies that align with the company’s objectives and mission. • Advise on regulatory matters affecting R&D, including clinical trials, product and companion diagnostics development, and submissions to regulatory authorities (e.g., FDA, EMA, CDE). • Stay current on developments in laws and regulations affecting the biotech industry and advise internal stakeholders accordingly. • Negotiate and draft a wide variety of agreements related to R&D, including collaboration agreements, licensing agreements, and clinical trial agreements. • Ensure that contracts are compliant with legal standards and aligned with the company’s strategic goals. • Collaborate closely with other departments to provide integrated legal support and guidance. • Serve as a key advisor and stakeholder to promote a culture of compliance and ethical conduct in R&D programs. • Build, lead, and mentor a high-performing legal team, fostering a collaborative and results-oriented environment. • Identify and evaluate potential legal risks associated with R&D activities and develop strategies to mitigate these risks. • Prepare and present legal analyses and recommendations to the executive team and Board of Directors. Qualifications: • 15+ years of relevant legal experience, which includes a focus on pharmaceutical, biotech, or related life science matters/clients, 5+ years of which should be in-house with a biotech/pharma company. • A U.S. law degree (J.D.) and current “good standing” admission to at least one U.S. state bar. • An ability to support global working hours. • Must have demonstrable mastery of human subject research protection laws; Federal Food, Drug and Cosmetic Act and related regulations; US and global privacy laws; US fraud & abuse laws; and other applicable federal and state laws governing the research and development of human therapeutics. • Must have significant experience involving clinical development programs, data sharing arrangements, clinical supply arrangements, companion diagnostic developments, complex research collaborations and consortia. Mandarin is a plus. • Proven knowledge of biotech law, regulatory requirements, and intellectual property issues in the context of drug development. • Strong negotiation and communication skills, with the ability to influence cross-functional stakeholders and drive legal initiatives. • Experience managing a legal team and providing strategic direction. • Exceptional analytical and problem-solving abilities, with a proactive approach to risk management. • Ability to approach complex problems with a creative and growth mindset, able to navigate risks by providing mitigation strategies and pragmatic solutions. • Experience with AI and digital health is helpful though not required, but a willingness to learn is a must. • Excellent verbal and written communication skills, awareness and ability to engage with others in a global ecosystem, along with a confidence for advising VP-level leadership and swiftly responding to and de-escalating as needed • Excellent judgment and superior business partnering skills, and the organizational savvy to effectively collaborate with and influence multidisciplinary global colleagues and external partners. • Ability to deliver clear, concise and practical advice and mitigation strategies regarding challenging legal issues to legal and non-legal colleagues, including senior management. • Ability to prioritize and work with agility across multiple projects. • Aptitude and interest to learn the scientific/technical side of the business. Supervisory Responsibilities: • Manage a global team Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Salary Range: $340,100.00 - $430,100.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com. BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 11,000 colleagues spans six continents. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn, X (formerly known as Twitter), Facebook and Instagram. For more information, please visit the link to explore job opportunities in China Mainland. China Mainland Job Posting At BeOne, how we work is just as important as the work we do. Below are our Values that determine the decisions we make and how we do things. Patients First Driving Excellence Bold Ingenuity Collaborative Spirit

Designing and governing enterprise data models to support analytics, AI, and regulatory compliance across R&D functions. | Requires 8+ years in strategic data modeling/architecture, deep pharma R&D expertise, and leadership skills, which do not match your legal and compliance experience. | BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. The Senior Manager R&D Data Modeler is responsible for designing, governing, and evolving enterprise data models that enable scalable analytics, AI, and regulatory-compliant data products across the R&D organization. This role combines hands-on data modeling expertise with cross-functional leadership, ensuring that conceptual, logical, and physical data models are accurate, extensible, and aligned with business and technology strategy. The Senior Manager R&D Data Modeler serves as a subject-matter expert across Research, Clinical, Safety, Regulatory, and related domains, partnering closely with data engineering, analytics, and governance teams to translate complex requirements into high-quality, production-ready and AI-ready data products. Essential Functions of the job: Strategic Data Architecture Define the enterprise modeling roadmap—aligning data architecture with long-term R&D objectives. Lead the design of advanced conceptual and logical frameworks that span Research, Clinical, Safety, Regulatory, and beyond. Advocate for modular, micro-service–friendly physical models to accelerate self-service analytics and AI. Ensure data models support downstream analytics, reporting, machine learning, and operational use cases. Governance & Tooling Define and enforce enterprise modeling standards, naming conventions, and design guidelines. Develop and oversee governance frameworks that institutionalize regulatory compliance, traceability, and auditability (GxP, FAIR principles and regulatory compliance at scale). Contribute to metadata, lineage, and data catalog initiatives by ensuring models are well-documented and discoverable. Evaluate emerging modeling paradigms (graph, knowledge-graph, metadata-driven) and pilot proof-of-concepts. Usage of and driving enterprise adoption of metadata repositories, lineage platforms, and model-driven development, leveraging AI models and tools. Cross-Functional Leadership Chair architecture councils and data governance boards to harmonize modeling standards across functions and to ensure consistency across domains and platforms. Collaborate with GTS/IT, and business sponsors to align priorities and deliverables related to modeling initiatives and data-product innovation. Thought Leadership & Mentorship Publish best-practice frameworks, reference architectures, and reusable design patterns to accelerate delivery. Mentor lead modelers and senior analysts—cultivating a center of excellence for data modeling and information management. Represent R&D data architecture at industry forums and conferences. Supervisory Responsibilities: No Computer Skills: Microsoft Applications (Outlook, Word, Excel, PowerPoint, Project) Qualifications: Master’s or Ph.D. in Data Science, Computer Science, or related discipline. 8+ years of strategic data modeling/architecture experience in regulated environments, deep Pharma R&D expertise strongly preferred. Proven ability to define and drive enterprise-scale modeling standards and tool migrations. Expert knowledge of modern data platforms (cloud-native, hybrid, graph databases) and advanced integration patterns. Exceptional leadership, influencing, and cross-stakeholder collaboration skills. Travel: Minimal BeiGene Global Competencies When we exhibit our values of Patients First, Collaborative Spirit, Bold Ingenuity and Driving Excellence, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Salary Range: $141,700.00 - $186,700.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com. BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 11,000 colleagues spans six continents. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn, X (formerly known as Twitter), Facebook and Instagram. For more information, please visit the link to explore job opportunities in China Mainland. China Mainland Job Posting At BeOne, how we work is just as important as the work we do. Below are our Values that determine the decisions we make and how we do things. Patients First Driving Excellence Bold Ingenuity Collaborative Spirit

Lead global HEOR/RWE strategies and evidence generation activities supporting a biopharmaceutical oncology asset across its lifecycle. | Requires advanced degree in HEOR, Epidemiology, or related field, with 5+ years in biopharma, and experience in oncology, HTA, and JCA submissions. | BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. General Description: The Global HEOR/RWE Director will provide strategic leadership for HEOR and RWE activities supporting a novel BTK degrader program across development, launch readiness, and lifecycle management. This role is accountable for developing and executing integrated value evidence generation strategy to support value proposition, differentiation, medical, regulatory, commercial and reimbursement needs across key markets. Core deliverables include real-world evidence generation, JCA/HTA submissions, global value dossier and US AMCP dossier, and health economic models. The Director will serve as a key cross-functional partner to medical, commercial, clinical development, and regulatory to ensure aligned evidence generation. This position requires strong research expertise, strategic thinking with understanding of reimbursement systems, communication and presentation skills, and the ability to lead and drive results in a matrix environment. Essential Functions of the Job: Lead global HEOR/RWE strategy and evidence generation activities for the BTK degrader asset across product lifecycle, ensuring alignment with cross-functional objectives Develop and execute integrated value evidence generation plan, including disease burden, treatment patterns, comparative effectiveness, indirect comparisons, economic modeling, and patient-centered outcomes to demonstrate clinical and economic value Design and execute real-world evidence and comparative effectiveness studies using various real-world data sources including claims and electronic health records to support differentiation Collaborate with cross-functional partners on JCA/HTA submissions and lead key HEOR deliverables timely including indirect comparisons and economic modeling Lead development of Global Value Dossiers and US AMCP dossier to support reimbursement submissions and value communication Lead development of health economic models, including cost-effectiveness and budget impact analyses Drive scientific dissemination of HEOR/RWE evidence through abstracts, manuscripts, and congress presentations and omnichannel distributions Partner cross-functionally with Clinical Development, Biostatistics, Medical Affairs, Regulatory, Commercial, and Market Access teams to integrate HEOR insights into overall program strategy Manage external vendors and research partners, overseeing study design, project executions, deliverables, timelines, and budgets Provide strategic HEOR guidance to affiliates and regional teams to support local evidence needs Supervisory Responsibilities: This position may include matrix leadership and oversight of external vendors and consultants Education Required: Advanced degree in Health Economics Outcomes Research (HEOR), Epidemiology, Public Health, Biostatistics, or related discipline PhD with 5+ years or Master’s degree with 7+ years of related experience in biopharmaceutical industry or consulting Hematology/Oncology experience strongly preferred Computer Skills: Proficiency in Microsoft Office, familiarity with statistical software, HEOR modeling tools and AI preferred Other Qualifications: Strong understanding of market dynamics and reimbursement landscape, with experiences supporting HTA and/or JCA submissions Proven success leading and executing evidence generation strategy and HEOR deliverables Demonstrated research expertise in designing and conducting HEOR/RWE studies, including indirect comparison, economic models and comparative effectiveness studies, with success in data dissemination and communication Impactful communication and presentation skills, with the ability to translate complex data and engage diverse stakeholders Innovative thinking and creative mindset with applied AI understanding to enhance evidence generation and HEOR insights Highly organized and self-motivated with ability to effectively prioritize and manage multiple projects, determine and meet objectives, timelines, and budget Ability to work in a cross-functional matrix team environment and effectively communicate and collaborate relevant HEOR/RWE strategies and activities with internal and external stakeholders Travel: Up to 15–20% as needed Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Salary Range: $185,300.00 - $245,300.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com. BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 11,000 colleagues spans six continents. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn, X (formerly known as Twitter), Facebook and Instagram. For more information, please visit the link to explore job opportunities in China Mainland. China Mainland Job Posting At BeOne, how we work is just as important as the work we do. Below are our Values that determine the decisions we make and how we do things. Patients First Driving Excellence Bold Ingenuity Collaborative Spirit

Lead the design, scaling, and adoption of AI-driven solutions across Commercial and Medical Affairs functions, translating enterprise AI strategy into scalable platforms and measurable outcomes. | Requires a PhD or Master's in AI, Data Science, or related field with 10+ years in data analysis, AI, or analytics, and experience leading complex AI initiatives, preferably in regulated industries like healthcare or pharma. | BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. General Description: BeOne Medicines is seeking a Senior Director, Innovation & AI to lead the design, scaling, and adoption of AI-driven solutions across Commercial and Medical Affairs functions. Reporting to the Vice President, Global Commercial & Medical Affairs technology, this role serves as a critical bridge between enterprise AI strategy and real-world execution, translating vision into scalable platforms, high-impact use cases, and measurable business outcomes for Commercial and Medical Affairs. The Senior Director will own a portfolio of AI initiatives, guiding multiple teams and programs that leverage advanced analytics, generative AI, Retrieval-Augmented Generation (RAG), and agentic AI approaches to improve decision-making, operational efficiency, and patient-centric innovation. This leader will partner closely with business, medical, and technology stakeholders across the globe to ensure AI capabilities are embedded into day-to-day workflows and strategic planning. This role requires a strong blend of business acumen, technical depth, strategic thinking, and people leadership, with accountability for delivery, adoption, and value realization of AI solutions aligned to BeOne’s business priorities. Strategic Partnership & Business Enablement Act as a senior thought partner to Commercial and Medical functional leaders, identifying opportunities where AI can materially improve performance, insight generation, and patient engagement. Guide teams in converting complex data and AI outputs into clear, actionable insights for senior leadership and business stakeholders. Drive adoption of AI-driven tools by embedding them into workflows, processes, and decision forums. Support global and regional teams by aligning AI initiatives across geographies while accounting for local needs and regulatory considerations. AI Solution Leadership & Delivery for Commercial & Medical Affairs functions Create a strategic roadmap for high value, high impact AI capabilities and lead execution for measurable outcomes. Translate enterprise AI strategy into prioritized roadmaps, ensuring timely delivery of high-impact, production-ready solutions. Oversee the evaluation, refinement, and performance monitoring of AI models to ensure accuracy, scalability, and sustained business value. Ensure AI solutions are designed with security, compliance, and responsible AI principles embedded from inception. Lead the design, development, and scaling of AI-driven platforms and solutions, including generative AI, RAG pipelines, and agentic AI systems, to support Commercial, Medical, and cross-functional decision-making and process automation. Portfolio & Program Management Own and manage a portfolio of AI and innovation initiatives, balancing near-term impact with longer-term capability building. Establish clear success metrics and governance mechanisms to track value realization, adoption, and ROI of AI investments. Coordinate dependencies across data, engineering, analytics, and business teams to ensure cohesive execution. Team Leadership & Capability Building Lead and mentor multiple teams of data scientists, AI engineers, as well as a matrix team of other technology functions to deliver AI solutions in the platforms they own. Set technical and delivery standards, fostering a culture of high-quality execution, experimentation, and continuous learning. Partner with the VP, AI & Innovation on roadmap, platforms, governance, and capability scaling. Partner with other Technology function leads to enable execution utilizing the rich data and enablement in Technology platforms. Innovation & External Awareness Stay abreast of emerging AI methodologies, tools, and platforms, assessing their relevance to BeOne’s business and scientific needs. Contribute to innovation strategy by piloting new approaches and transitioning successful concepts into scaled solutions. Collaborate with external partners, vendors, and internal centers of excellence as needed to accelerate delivery. Education Required: Master’s or PhD in AI, Engineering, Data Science, Statistics, Computer Science, or a related quantitative field. Qualifications: Experience Master’s or PhD in AI, Engineering, Data Science, Statistics, Computer Science, or a related quantitative field with 10+ years of experience in data analysis, AI, advanced analytics, data science, or related disciplines, including consulting experience, with demonstrated progression into leadership roles. Experience operating in regulated industries (life sciences, healthcare, pharma preferred). Proven experience leading complex, cross-functional AI initiatives from concept through enterprise-scale deployment. Technical & Analytical Expertise Strong analytical skills with the ability to work with complex datasets, interpret trends, and translate analytical outputs into clear business insights. Strong working knowledge of generative AI, Retrieval-Augmented Generation (RAG), and agentic AI approaches. Experience guiding teams using NLP, machine learning, deep learning, and predictive analytics across structured and unstructured data. Familiarity with modern AI and data platforms (e.g., cloud environments, Databricks, Snowflake, vector databases, AI orchestration frameworks). Ability to evaluate AI architectures and trade-offs without needing to be the primary hands-on developer. Leadership & Business Acumen Strong business acumen and deep understanding of commercial market data, with the ability to translate business needs and market insights into scalable AI-enabled solutions that drive measurable commercial impact. Demonstrated ability to translate complex AI concepts into business-relevant insights and recommendations. Strong stakeholder management and influencing skills across senior business, medical, and technology leaders. Experience leading teams, setting direction, and driving accountability for outcomes. Excellent communication and executive storytelling skills. Travel: Estimated 10-15%, primarily for key planning sessions, workshops, or major launch initiatives. Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Salary Range: $207,800.00 - $277,800.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com. BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 11,000 colleagues spans six continents. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn, X (formerly known as Twitter), Facebook and Instagram. For more information, please visit the link to explore job opportunities in China Mainland. China Mainland Job Posting At BeOne, how we work is just as important as the work we do. Below are our Values that determine the decisions we make and how we do things. Patients First Driving Excellence Bold Ingenuity Collaborative Spirit

Transform complex data into actionable insights to support pharmacovigilance and regulatory decisions, develop dashboards, and collaborate with stakeholders. | Advanced degree in Data Science, Statistics, or related field; 6+ years in data analytics, with experience in pharma or healthcare; proficiency in Python, R, and data visualization tools; experience with AI/ML frameworks and cloud platforms. | BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. We are seeking an experienced professional to contribute to our safety and regulatory data analytics initiatives. This role is responsible for transforming data into actionable insights that will drive business decisions, enhance patient outcomes, and optimize product development. The role will serve as a key partner to drive data-driven operation and decisions with the clinical development stakeholders. Essential Functions of the Job Data Analytics & Interpretation: Contribute to the analytics strategy and roadmap by collaborating with business stakeholders across portfolio Deliver analytics dashboards or tools that support pharmacovigilance (safety signal detection, integrated safety review, risk evaluation and safety operation using clinical trial, real-world and post-marketing surveillance data) and regulatory affairs (submission times, response tracking, etc.) that align with business functional goals Utilize advanced analytics, machine learning, and artificial intelligence techniques to identify trends, patterns, and opportunities within complex datasets, directly applying these capabilities to address business challenges. Ensure the accuracy, integrity, and security of data to meet compliance standards and regulatory requirements. Stakeholder Engagement: Translate business questions from study teams into well-structured analyses with actionable recommendations. Understand the business and the organizations, become familiar with business process, leveraging a strong business acumen Act as a key point of contact and partner to product managers and business functions to define KPIs, OKRs, metrics pertaining to pharmacovigilance and regulatory affairs, develop and implement role-based dashboards or analytical tools to track business operations, performance and suggest data-driven next best actions. Innovation and Continuous Improvement: Stay abreast of industry trends, emerging technologies, and best practices in data analytics and insights to drive innovation within the organization. Hands-on experience in implementation and operationalizing AI/ML solutions in business context, technically proficient in various algorithms and models Identify and improve processes continuously, explore the opportunities of doing things differently and smartly Qualifications: Master’s or PhD in Data Science, Statistics, Computer Science, Life Sciences, or a related field 6+ years of experience in data science, analytics, insights, or related fields, with at least 2+ years in the pharmaceutical industry Excellent communication and presentation skills, with the ability to convey complex data insights to non-technical stakeholders Strong interpersonal skills and the ability to lead cross-functional teams and influence at all levels of the organization Strong capability of prioritizing and handling multitasks, executing quickly Be able to work under pressure Exceptional analytical, problem-solving, and critical-thinking skills Self-motivated, hands-on, disciplined and proactive person with great team-work spirit and strong accountability Computer Skills: Familiar with clinical systems, e.g., EDC, Argus, CTMS, IRT and other systems Hands-on experience with AI/ML frameworks and libraries to develop algorithms in business context. Familiarity with LLMs and Agentic AI is a strong plus Experience with data visualization tools (e.g., Spotfire, PowerBI) and familiarity with cloud platforms Strong proficiency in data analysis tools and programming languages (such as Python and R) Familiarity with Databricks is a plus Education Required: Master’s or PhD in Data Science, Statistics, Computer Science, Life Sciences, or a related field BeOne Global Competencies: When we exhibit our values of Patients First, Collaborative Spirit, Bold Ingenuity and Driving Excellence, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Salary Range: $121,400.00 - $161,400.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com. BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 11,000 colleagues spans six continents. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn, X (formerly known as Twitter), Facebook and Instagram. For more information, please visit the link to explore job opportunities in China Mainland. China Mainland Job Posting At BeOne, how we work is just as important as the work we do. Below are our Values that determine the decisions we make and how we do things. Patients First Driving Excellence Bold Ingenuity Collaborative Spirit

Lead clinical development programs, oversee study execution, and support regulatory interactions for oncology therapeutics. | Advanced degree (MD, PhD, PharmD) with 8+ years in biotech/pharma, expertise in oncology, translational medicine, and global clinical development experience. | BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. The Executive Director, Clinical Development will lead clinical development of at least one high impact project, determining the most expeditious path to progress for patients, and charting a course for the next wave of multifunctional assets at BeOne. Reporting to the VP of Clinical Development, the candidate will support BeOne Medicine’s clinical and medical assets by successful execution of clinical development programs and deliverables in partnership across the organization; with external vendors; and with external academicians and collaboration partners. As a leader in the organization, the incumbent will be accountable to jointly develop clinical program strategy and help assure that activities are executed within expected scope, budget, and timelines. The incumbent will play a key role in the establishment and growth of Clinical Research functions to assure best-in-class global capabilities and execution. Specifically, the incumbent will work closely with colleagues in clinical development, program leadership, biometrics, clinical operations, safety/pharmacovigilance, regulatory, molecular diagnostics, and translational research. Key Roles and Responsibilities: Key contributor in Clinical Development strategy, planning, and leading presentations to various internal governance committees Provide leadership and clinical oversight for all assigned studies and programs, including at least one ground-breaking early phase project with clinical applications across tumor types, and one mature project with substantial ongoing registrational activities Seamless transition of drug candidates from research to early clinical development Effective integration of in-licensed drug candidates into clinical development portfolio Effective development of assets according to stringent criteria Effective transition of assets from early to late clinical development Significant contribution and oversight of clinical development activities in support of worldwide Health Authority interactions Engagement with KOL’s and Collaborators Training of clinical team and other functional teams, as appropriate Assessment of Investigator Initiated and Collaborator Research program Essential Functions of the Job: Facilitate generation of, author, update, and/or review key documents Protocol concepts, synopses, protocols, and amendments Informed consent documents Investigator Brochures Clinical Study reports Abstracts, posters, and manuscripts Clinical sections of INDs (and equivalent applications), NDAs (and equivalent applications), Annual Reports, and Developmental Safety Update Reports Clinical sections of Health Authority Briefing Documents, Orphan Drug applications, and annual reports Risk/Benefit analysis for applicable documents Clinical Development Plans Partner with clinical operations and other functional areas for the successful implementation and execution of clinical studies Provide scientific expertise for selection of investigator and vendors Train BeOne colleagues, CRO staff, and study site staff on the therapeutic area, molecule, and/or clinical protocol Provide scientific and medical support throughout conduct of a clinical trial; respond to clinical questions from sites, IRBs/IECs, Health Authorities, and CROs Review, query, and analyze clinical trial data Interpret and present clinical trial data both internally and externally Represent a clinical study or development program on one or more teams or sub-teams Create clinical study or program-related slide decks for internal and external use Build and maintain opinion leader/investigator networks; organize and present at key opinion leader advisory boards and investigator meetings Understand competitive clinical development landscape, contribute to or perform therapeutic area/indication competitor research and adjust strategy accordingly Identify strategic and incremental organizational resource needs re: People, Process, and Technology Build strong relationships with internal experts Identify continuous process improvement opportunities Identify incremental organizational resource needs – staff, budget, and systems Develop, track, execute, and report on goals and objectives Support budget planning and management Be accountable for compliant business practices Education and Experience Required: Advanced degree in a relevant scientific or clinical discipline (e.g. MD, PhD, or PharmD) with a minimum of 8+ years of experience and success within biotech/pharmaceutical industry and/or equivalent experience in academia Professional knowledge and skills working in oncology therapeutics across solid tumor types is required Proficiency in translational medicine is required Strategic leader with demonstrated success building, managing, and developing individuals and teams Working knowledge of applicable International Compliance guidelines and regulations is expected Experience working in a global environment is required Experience with the development and support of related SOP’s and policies is expected Experience with partnerships and strategic alliances is expected Extensive history of participation in filing activities leading to global approvals is preferred Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Salary Range: $329,700.00 - $409,700.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com. BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 11,000 colleagues spans six continents. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn, X (formerly known as Twitter), Facebook and Instagram. For more information, please visit the link to explore job opportunities in China Mainland. China Mainland Job Posting At BeOne, how we work is just as important as the work we do. Below are our Values that determine the decisions we make and how we do things. Patients First Driving Excellence Bold Ingenuity Collaborative Spirit

Lead enterprise CRM and digital ecosystem strategy, architecture, content management, and global operations. | Over 18 years in CRM, digital transformation, and enterprise platform leadership, with senior experience in regulated environments, and expertise in pharma or life sciences digital ecosystems. | BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. General Description: BeOne Medicine is seeking an Executive Director, CRM Strategy & Digital Excellence to define and lead the evolution of CRM and digital enablement across Commercial and Medical Affairs globally. This role is responsible for shaping an enterprise-grade CRM and digital engagement and content infrastructure that transforms customer engagement, drives insight-led decision-making, and ensures scalable, compliant, and future-ready digital capabilities. Reporting to the VP, Global Commercial & Medical Affairs Technology, the Executive Director will own the end-to-end CRM and digital ecosystem, spanning CRM platforms, digital and web technologies, content and MLR platforms, data and integration foundations, operational excellence, and innovation. This leader will partner closely with Commercial, Medical, Market Access, Data, Compliance, Legal, and IT leadership to ensure CRM and digital platforms operate as a unified, intelligent engagement layer within BeOne's modular technology stack. Essential Functions of the Job: Enterprise CRM & Digital Strategy: • Define and drive BeOne's CRM and Digital Engagement North Star, encompassing CRM, web, content, and omnichannel engagement platforms. • Develop and execute a multi-year roadmap spanning CRM capabilities, digital and web infrastructure, content platforms, integration architecture, and experience modernization. • Position CRM and digital platforms as systems of intelligence and execution, tightly integrated with analytics, marketing automation, and AI capabilities. • Serve as a strategic advisor to senior Commercial and Medical leadership, ensuring digital investments deliver measurable business outcomes. Digital Infrastructure, Web & Platform Excellence: • Own the CRM, digital, and web platform architecture, ensuring scalability, resilience, interoperability, and compliance across global markets. • Provide executive oversight for web technologies supporting HCP, patient, and institutional engagement (e.g., CMS platforms, microsites, portals), ensuring alignment with CRM and omnichannel strategies. • Establish standards for digital infrastructure, including: • Cloud platforms and environments • Integration layers (APIs, middleware, event-based architectures) • Identity, consent, and access management • Content delivery and experience layers • Ensure architectural alignment across CRM, web, marketing automation, analytics, and enterprise data platforms. • Drive modernization initiatives while maintaining operational stability and regulatory compliance. Content, MLR & Digital Asset Enablement: • Own the digital content and MLR ecosystem, ensuring seamless integration between CRM, marketing, web, and field engagement platforms. • Provide strategic oversight for MLR platforms and workflows, enabling efficient content creation, review, approval, versioning, and reuse. • Establish enterprise standards for content tagging, taxonomy, and metadata, enabling: • Intelligent content reuse across channels • Personalization and next-best-action use cases • Accurate tracking, reporting, and compliance • Partner with Commercial, Medical, Legal, and Compliance teams to ensure content processes are scalable, compliant, and audit-ready. • Enable AI-driven content discovery, recommendation, and orchestration through structured metadata and taxonomy frameworks. Global CRM & Digital Operations: • Lead the CRM & Digital Center of Excellence (CoE), encompassing CRM, web, content platforms, and supporting infrastructure. • Establish and enforce global standards for configuration, release management, validation, and change control across CRM and digital platforms. • Oversee vendor strategy across CRM, web, MLR, CMS, and digital experience platforms. • Monitor platform performance, adoption, and user experience; drive continuous improvement initiatives. Data, Insights & Compliance Enablement: • Partner with Data Management, Analytics, and AI teams to ensure CRM, web, and content data quality and governance. • Embed compliance-by-design across CRM, web, and content workflows, including consent, activity tracking, auditability, and promotional compliance. • Ensure digital platforms support trusted reporting, analytics, and AI-driven engagement use cases. • Champion KPI-driven governance across CRM and digital platforms, measuring adoption, engagement effectiveness, and ROI. User Experience, Adoption & Change: • Lead enterprise change management for CRM, web, and digital platforms across field and headquarters teams. • Oversee global training and enablement programs spanning CRM usage, digital content workflows, and omnichannel execution. • Drive user-centric and field-first design, simplifying workflows, surfacing insights, and automating manual tasks. • Establish continuous feedback loops between users, business stakeholders, and technology teams. Innovation & Future Readiness: • Introduce and scale AI-enabled CRM and digital capabilities, including next-best-action, intelligent content recommendations, and omnichannel orchestration. • Partner with Innovation & AI teams to pilot and industrialize emerging digital and AI capabilities. • Explore integration with patient, institutional, and ecosystem platforms to enable a 360° stakeholder view. • Stay ahead of emerging trends in CRM, web, content management, and digital engagement. Required Education: • Bachelor's degree in Business, Life Sciences, Engineering, or Information Technology required. • Advanced degree (MBA, MS, or equivalent) strongly preferred, with focus on Digital Transformation, Commercial Excellence, or Data Strategy. Qualifications: • BA/BS degree with 18+ years of progressive experience in CRM, Commercial Operations, Digital Strategy, or Enterprise Platforms within life sciences. • 7 + years in senior leadership roles, owning global CRM and/or digital platform portfolios. • Proven track record leading large-scale, global CRM and digital transformations in regulated environments. Domain & Technology Expertise: • Deep understanding of pharmaceutical commercial and medical engagement models. • Expertise with CRM platforms (Salesforce Health Cloud, Veeva CRM, or equivalent). • Strong knowledge of digital infrastructure and integration patterns (APIs, middleware, cloud platforms). • Familiarity with AI-driven CRM use cases, omnichannel engagement, and analytics integration. • Solid grounding in data privacy, security, and compliance (GDPR, HIPAA, Sunshine, etc.). Leadership & Transformation Skills: • Executive-level stakeholder management and influencing capabilities. • Demonstrated success leading cross-functional, global teams and Centers of Excellence. • Strong governance, vendor management, and financial oversight experience. • Ability to balance innovation, risk management, and operational rigor. • Clear, compelling communicator with strong executive presence. Supervisory Responsibilities: • Yes Computer Skills: • PC, including MS Office Suite Travel: • 20-30% Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. • Fosters Teamwork • Provides and Solicits Honest and Actionable Feedback • Self-Awareness • Acts Inclusively • Demonstrates Initiative • Entrepreneurial Mindset • Continuous Learning • Embraces Change • Results-Oriented • Analytical Thinking/Data Analysis • Financial Excellence • Communicates with Clarity Salary Range: $267,400.00 - $347,400.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com.

Designs engaging, scalable learning experiences for global quality initiatives, translating complex regulatory content into learner-friendly materials, and continuously evaluating training effectiveness. | Requires 7+ years of instructional design experience with GXP and quality systems, managerial experience, and proficiency with learning technologies. | BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. General Description: The Instructional Designer, Global Quality plays a pivotal role in shaping how quality principles, compliance expectations, and continuous improvement mindsets are learned, applied, and sustained across the organization. Combining deep expertise in Quality Management Systems (QMS) with advanced knowledge of adult learning theory, cognitive psychology, and behavioral science, this role designs engaging, scalable, and high-impact learning experiences that directly support global quality excellence. By transforming complex regulatory concepts into clear, learner-centered training, the Instructional Designer ensures that employees at all levels develop the behaviors, capabilities, and confidence needed to maintain a strong culture of quality worldwide. This position partners closely with global quality leaders, subject matter experts, and regional training teams to create innovative multi-modal learning solutions—including eLearning, instructor-led training, simulations, microlearning, and performance support tools—that drive measurable performance outcomes. Through the integration of learning science and behavior-change models, the Instructional Designer fosters continuous learning, promotes proactive problem-solving, and enhances operational readiness. This role not only delivers impactful training but also continuously evaluates and improves learning effectiveness to ensure alignment with corporate quality strategies, regulatory requirements, and organizational goals. Essential Functions of the Job: Lead the Full Instructional Design Lifecycle Conduct needs analysis, design learning objectives, develop instructional content, and evaluate effectiveness using measurable performance outcomes. Ensure learning solutions are engaging, compliant, and aligned with both global quality standards and business priorities. Design High-Impact QMS Learning Experiences Develop engaging and scalable learning solutions for global quality initiatives, including GxP compliance, deviation management, CAPA, document control, change management, and inspection readiness. Create high-quality learning experiences, including instructor-led training (ILT), virtual ILT (vILT), eLearning, hands-on skill labs, simulations, and performance support tools. Apply adult learning theory, cognitive load management, and instructional design best practices to create effective and efficient learning interventions. Integrate Learning Science and Behavior Change Models Leverage models such as Social Cognitive Theory and the Transtheoretical Model of Behavior Change to promote skill transfer, accountability, and sustained performance improvement. Embed growth mindset principles into QMS training to encourage proactive problem-solving and continuous learning. Streamline workflows to improve efficiency, scalability, and learner experience. Collaborate Across Global Quality and Learning Teams Partner with subject matter experts (SMEs), global quality leaders, and regional training coordinators to translate complex regulatory content into learner-friendly materials. Ensure alignment with corporate quality strategies, learning technologies, and regulatory expectations. Develop and Deliver Multi-Modal Learning Content Prepare and deliver train-the-trainer sessions to ensure regional and functional trainers can deliver content with consistency and impact. Support the scalability and sustainability of global learning programs. Incorporate storytelling, scenario-based learning, and microlearning techniques to enhance knowledge retention and real-world application. Collaborate with L&D leaders, instructional designers, trainers, and HR teams to align learning technology with business needs. Evaluate and Continuously Improve Training Effectiveness Use learning analytics and feedback to measure comprehension, confidence, and behavior change. Apply data insights to refine instructional strategies and improve overall learning outcomes and operational impact. Education and Experience Required: Bachelor’s degree and 7+ years of Instructional Design, adult Learning and GXP Training Curriculum experience required Master’s degree and 5+ years of Instructional Design, adult Learning and GXP Training Curriculum experience required Supervisory Responsibilities: 3 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources. Computer Skills: Experience with mobile learning solutions, knowledge or LMS and LXP platforms. Proficient in Microsoft, Articulate suite, Synthesia, Vyond, Cognota, Degreed, WalkMe Other Qualifications: Travel: Up to 20% Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Salary Range: $133,200.00 - $178,200.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com. BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 11,000 colleagues spans six continents. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn, X (formerly known as Twitter), Facebook and Instagram. For more information, please visit the link to explore job opportunities in China Mainland. China Mainland Job Posting At BeOne, how we work is just as important as the work we do. Below are our Values that determine the decisions we make and how we do things. Patients First Driving Excellence Bold Ingenuity Collaborative Spirit

Support and execute digital Quality Systems strategy, lead system lifecycle management, and collaborate across functions to ensure compliance and process optimization. | 7+ years in Life Science or related fields, experience with enterprise system implementations, and understanding of GxP regulations. | BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. General Description: The Senior Manager, Digital Quality Management Systems Business Analyst position is responsible for supporting and executing the strategy, implementation, and lifecycle management of digital Quality Systems. This role serves as a key liaison between Quality, IT, and business stakeholders, ensuring that technology solutions are aligned with business requirements, business goals, and industry best practices. The role balances traditional Quality Management System (QMS) responsibilities with cross-functional project leadership, system ownership, and process optimization to drive GxP compliance and enhance digital maturity. Essential Functions of the Job: Serve as the business System Owner for assigned Quality GxP digital systems (e.g., eQMS, QualityDocs, etc). Lead and manage full lifecycle of system implementations and enhancements. Gather and translate complex business needs into functional and technical requirements. Drive process mapping, continuous improvement, and digital transformation initiatives across Quality. Collaborate with cross-functional teams including QA, IT, Regulatory, Clinical, and external vendors to align systems with business strategy. Develop and maintain strong relationships with business process owners and ensure systems meet evolving needs. Plan and lead UAT, training, and change management activities for new system features or implementations. Manage project scope, timeline, resources, budgets, and risks, escalating issues as needed. Ensure ongoing system compliance with applicable GxP, FDA, EMA, and ISO standards. Prepare and deliver high-quality project updates, stakeholder communications, and system documentation. Oversee the governance, configuration, and administration of digital quality tools such as Veeva QMS, ensuring alignment with organizational policies and compliance standards while optimizing system functionality to enhance user experience and operational efficiency. Develop and implement master data management practices to ensure data accuracy, consistency, and integrity across digital quality tools, facilitating informed decision-making and compliance with regulatory requirements. Perform other duties, as assigned. Education and Experience Required: Bachelor’s degree and 7+ years of Life Science, Engineering, Information Systems, or related experience in a regulated life sciences environment required of Master’s degree and 5+ years of Life Science, Engineering, Information Systems, or related experience in a regulated life sciences environment preferred Supervisory Responsibilities: N/A Computer Skills: Proficient in Microsoft Office, Smartsheet, Teams, and project management tools (e.g., JIRA, MS Project). Other Qualifications: 7+ years of related experience in Quality Systems, project management, and business analysis Strong understanding of GxP requirements, Quality System Regulations (QSR), and validation practices. Proven experience managing enterprise system implementations (e.g., Veeva Vault, SAP, etc.). Experience in business administration for Veeva QMS. Skilled in process modeling, requirements gathering, risk assessment, and stakeholder facilitation. Excellent interpersonal, communication, and organizational skills. Lean Six Sigma or Agile certification preferred. Travel: Up to 15% Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Salary Range: $133,200.00 - $178,200.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com. BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 11,000 colleagues spans six continents. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn, X (formerly known as Twitter), Facebook and Instagram. For more information, please visit the link to explore job opportunities in China Mainland. China Mainland Job Posting At BeOne, how we work is just as important as the work we do. Below are our Values that determine the decisions we make and how we do things. Patients First Driving Excellence Bold Ingenuity Collaborative Spirit

Oversee business strategy and operational management for a global R&D technology organization, including process optimization, data governance, and team leadership. | Extensive experience in business strategy and operations within data, digital, and IT organizations, with strong technical expertise in cloud/SaaS environments, data principles, and governance. | BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. BeOne is a global biopharmaceutical company dedicated to the discovery and development of innovative drug therapies for the treatment of cancer. The Global Technology Solutions (GTS) organization is responsible for data, digital, technology & AI infrastructure, platforms, systems, and services that provide the foundation, maturity, governance, and innovation needed to serve patients around the world. At BeOne we believe that access to life-changing medicine sees no borders, and GTS makes this possible by delivering a cloud-based backbone and SaaS systems for efficient delivery, growth, and maintenance, while positioning our staff to demonstrate their domain, technical, and governance expertise as partners of the BeOne global team. General Description: The Executive Director, Strategy & Business Operations, Global R&D Technology Solutions is responsible for the overall business strategy & operational management of the processes, programs, governance bodies and capability areas that the Global R&D Technology Solutions organization needs for successful delivery of its business outcomes. As a member of the GRDTS Leadership Team, the Executive Director is an active contributor to developing and executing GRDTS’ business strategy & defining, developing & operationalizing key capability areas. A successful candidate is a dynamic leader and business relationship manager who brings deep end-to-end R&D domain knowledge, advanced skills in operations management & strategy with technical expertise in foundational FAIR data principles, technology platforms, cloud/SaaS environments, products and tools. Strong experience in cloud/SaaS environments, ability to manage multiple projects across different functions in a global, geographically diverse environment, and building and sustaining teams in times of ambiguity are all critical success factors for this role. An ideal candidate will adapt communication cadences and problem-solving skills to accommodate customers, partners, and team members, exercise diplomacy and effective influence to reach consensus, and build strong stakeholder relationships. Essential Functions of the job: Strategy & Business Operations Leader for the GRDTS organization Business Strategy & Operational Plan Development: Consult with the GRDTS LT to understand R&D’s functional strategy, priorities, and unmet data/technology/process needs and create a business strategy and an operational plan for the GRDTS organization to successfully deliver on its annual goals. Establish Key Performance Indicators (KPIs) and success metrics to track progress against enterprise goals and ensure the strategy remains adaptable to shifting market conditions. Process Optimization & Innovation: Define, design and stand-up a process optimization capability area within GRDTS. Capability remit will include assessment of new & existing workflows to design optimized processes by leveraging automation, data, digital, technology tools, ML, AI, and Generative AI. Establish a continuous improvement framework and conduct ROI analysis on automation initiatives to ensure technology investments deliver tangible productivity gains. FAIR Data & Ontology: Partner with R&D and Business Partner teams within GRDTS to implement comprehensive FAIR data, technology & methods strategies (Findable, Accessible, Interoperable, Reusable). Lead the conceptualization, design, development & implementation of anontology framework including roles, permissions, workflows, and standards for the creation, management, evolution, and use of ontologies across the organization, including oversight of the following components: End-to-end design, development, and management of domain-specific ontologies Key concepts, terms, and relationships Translation of the conceptual model from SMEs into a formal, machine-readable ontology language (like OWL or RDF). Working as a bridge between domain knowledge and technical implementation. Ensuring the ontology is accurate, up-to-date, and aligns with an upper ontology as necessary. Ensuring the ontology can be effectively used across different systems and applications. Selection and use of appropriate technology and tools (e.g., ontology editors, graph databases, specific software development kits) to support the ontology's lifecycle. Technology Governance: Coordinate the activities of governance bodies responsible for the alignment of technical investments with business priorities. Integrate risk management, security compliance, and vendor assessment into the governance process to mitigate technical debt and ensure a scalable infrastructure. Portfolio & Budget Management: Direct the organization’s program portfolio and financial budget, including resource capacity planning and financial forecasting. Design and implement a Total Cost of Ownership (TCO) framework to capture and model the full lifecycle costs—including acquisition, implementation, cloud consumption, and maintenance. Establish TCO tracking and auditing mechanisms to monitor variance and ensure financial transparency across all organizational investments. Organizational Communications: Develop and execute a comprehensive internal communication strategy to ensure information, services, products, processes etc. from GRDTS & other GTS organizations are shared effectively with R&D stakeholders and GRDTS team members. Author newsletters and executive announcements tailored to diverse stakeholders and implement feedback loops to measure and improve communication effectiveness. Vendor Management: Identify, evaluate, and manage strategic technology vendors who provide cutting-edge scientific software and / or AI/ML capabilities, as needed. GRDTS Leadership: Team Leadership & Talent Development: Lead, mentor, and manage a high-performing GRDTS team focused on business strategy, operations, portfolio management, process optimization & ontologies. Operational Excellence, Compliance & Governance: Ensure all systems and data platforms adhere to relevant pharmaceutical industry regulations and internal GTS security policies. Liaise with computer system vendors, IT partners, audit, and compliance to coordinate system implementation and change activities Ensure team is trained in and embeds CSV, compliance, and health authority requirements into operational activities. Manage the GRDTS portfolio's budget, resource allocation, and project prioritization process to maximize return on investment. Collaboration & Data Foundation: Collaborate with other GRDTS business partners on standards and best practices. Lead and support Global Technology Solutions (GTS) initiatives to support its growth and maturity. Engage with peers to define, sponsor, and execute continuous improvements. Supervisory Responsibilities: Lead, mentor, and manage a high-performing GRDTS team dedicated to business strategy, operations, portfolio management, process optimization & ontologies. Other Qualifications: 14+ years of professional experience in business strategy & operations in a data, digital & information technology organization with direct oversight and experience in R&D function-related data & technologies in the Pharmaceutical, Biotechnology, and/or Medical Device industries Strong experience in data & analytic methods and technologies Business relationship management acumen and demonstrable success as a change agent leading or contributing to significant transformational initiatives in organizations. Strong experience with software lifecycle methodologies, 21CFR Part 11 compliance, and GxP computer systems validation (CSV). Accomplished in building and development of people and teams, comfortable working with a broad cross section of people in direct and matrixed relationships Proficient in various project management disciplines (i.e., Agile, Scrum, Kanban, Lean etc.) Travel: Some travel expected as part of assigned duties Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Salary Range: $267,400.00 - $347,400.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com. BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 11,000 colleagues spans six continents. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn, X (formerly known as Twitter), Facebook and Instagram. For more information, please visit the link to explore job opportunities in China Mainland. China Mainland Job Posting At BeOne, how we work is just as important as the work we do. Below are our Values that determine the decisions we make and how we do things. Patients First Driving Excellence Bold Ingenuity Collaborative Spirit

Lead global quality initiatives, ensure product quality standards, and foster expertise in emerging quality technologies within a regulated industry. | Extensive experience in quality sciences, regulatory requirements, and leadership in quality investigations and risk management, with a preference for advanced degrees and managerial experience. | BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. General Description: The Product Quality Lead, as part of the Quality Sciences and Knowledge Management organization, will play a critical role in advancing global quality initiatives, ensuring the highest standards of product quality, and fostering expertise in emerging quality technologies. This position will contribute to quality risk management, knowledge-sharing strategies, and the development of technical training programs to strengthen compliance, operational excellence, and innovation. The PQL will support cross-functional collaboration, drive process improvements and enhance the organization's approach to quality governance. This individual will collaborate across functions and sites to drive continuous improvement, ensure regulatory compliance, and build a robust knowledge-sharing and risk management culture. Represent the Quality Organization at platform level through participation in molecule level governance meetings and forums. Serve as a Subject Matter Expert (SME) and Facilitator for quality risk assessment, investigations, change control, and resolution of complex quality issues including review of regulatory CMC submission content Manage Product Quality Network teams responsible for deliverables for multiple late-phase clinical or commercial programs Collaborate with R&D, manufacturing (CMC) and regulatory teams to ensure quality considerations are embedded in new product development and lifecycle management. Advise on CMC strategies and quality risk management for commercialization including strategies for in process controls, specifications, stability, and comparability Contribute to product quality performance monitoring, identifying trends and driving improvements. Lead or participate in cross-functional teams to improve quality systems and address systemic challenges. Support the development and implementation of Quality Risk Management (QRM) frameworks, ensuring compliance with regulatory requirements (e.g., ICH Q9). Support regulatory inspections and audits, ensuring alignment with global quality standards and best practices. Actively mentoring new and existing team members to develop core Product Quality skills and leadership skills Understanding and responding to the impact of emerging scientific/technical trends and their implications for BeOne / BeiGene Products. Perform other related responsibilities as assigned. Education/Experience Required: Bachelor’s degree and 8+ years of experience in quality sciences, quality systems, or related fields within a regulated industry (e.g., pharmaceuticals, biotechnology, medical devices). Master’s degree and 10+ years experience preferred Supervisory Responsibilities: 5 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources. Computer Skills: Strong PC literacy required; MS Office skills (Outlook, Word, Excel, PowerPoint). Experience in statistical modeling software (Mintab, JMP, Tableau, SciLab Other Qualifications: Advanced degree in life sciences, quality management, or related field Extensive experience in leading quality investigations, quality risk management, and implementing new technologies. Expertise in quality systems, regulatory requirements (e.g., FDA, EMA), and risk management frameworks (e.g., ICH Q9). Strong leadership and problem-solving skills, with the ability to manage complexity and ambiguity. Experience in developing and delivering global training programs ad fostering SME networks. Proficiency in quality tools and methodologies (e.g., root cause analysis, Lean, Six Sigma). Ability to communicate complex information clearly and effectively across business functions Travel: Up to 20% Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Salary Range: $172,000.00 - $232,000.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com. BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 11,000 colleagues spans six continents. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn, X (formerly known as Twitter), Facebook and Instagram. For more information, please visit the link to explore job opportunities in China Mainland. China Mainland Job Posting At BeOne, how we work is just as important as the work we do. Below are our Values that determine the decisions we make and how we do things. Patients First Driving Excellence Bold Ingenuity Collaborative Spirit

Lead global R&D technology strategy for Clinical Pharmacology & Development, overseeing data, digital, AI/ML platforms, and vendor management. | Over 14 years in data, digital & IT, with 7+ years in biotech/pharma, leadership experience, and expertise in AI/ML, GxP, and GxP-compliant systems. | BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. BeOne is a global biopharmaceutical company dedicated to the discovery and development of innovative drug therapies for the treatment of cancer. The Global Technology Solutions (GTS) organization is responsible for data, digital, technology & AI infrastructure, platforms, systems, and services that provide the foundation, maturity, governance, and innovation needed to serve patients around the world. At BeOne we believe that access to life-changing medicine sees no borders, and GTS makes this possible by delivering a cloud-based backbone and SaaS systems for efficient delivery, growth, and maintenance, while positioning our staff to demonstrate their domain, technical, and governance expertise as partners of the BeOne global team. General Description: The Executive Director, Global Clinical Pharmacology & Development Technology Solutions is the principal Global R&D Technology Solutions (GRDTS) leader and business partner to the BeOne Global Clinical Pharmacology & Development functions. The Global Business Partner and their team help define business objectives, engineer technical solutions, and build and maintain the portfolio of Clinical Pharmacology & Development solutions, while applying principles of innovation and efficiency. As a member of the GRDTS Leadership Team, the Executive Director is an active contributor to developing and executing BeOne’s R&D technology strategy, defining necessary technology investments, and driving transparency in prioritization and planning. The Executive Director and their team are responsible for ensuring the strategy is fully aligned with business needs, positioning GTS services to deliver and realize compelling business value. The Executive Director closely manages the landscape of data, technology, applications and solutions used by Clinical Pharmacology & Development and their functional portfolio of projects. They collaborate with other GTS R&D Business Partners to identify risks, interdependencies, and opportunities to inform financial responsibility, robust planning, and reliable execution, and partners with GTS Shared Services & Centers of Excellence (CoEs) to ensure adherence to BeOne’s technology architecture, security & compliance, and system and project life cycle governance. A successful candidate is a dynamic leader and business relationship manager who brings deep end-to-end biotech Clinical Pharmacology & Development domain knowledge with technical expertise in digital transformation, data science, analytics, AI, genAI, and integration tools and platforms. Strong experience in cloud/SaaS environments, ability to manage multiple projects across different functions in a global, geographically diverse environment, and building and sustaining teams in times of ambiguity are all critical success factors for this role. An ideal candidate will adapt communication cadences and problem-solving skills to accommodate customers, partners, and team members, exercise diplomacy and effective influence to reach consensus, and build strong stakeholder relationships. Essential Functions of the job: Data, Digital & Technology Business Partnership to the Clinical Pharmacology & Development Functions Strategic Alignment & Roadmap Development: Serve as the primary GTS strategic partner to the Clinical Pharmacology & Development functions to understand their scientific strategy, priorities, and unmet data/technology needs. Define and own the multi-year Data, Digital & Technology Roadmap for Clinical Pharmacology & Development, ensuring it directly enables key scientific milestones, accelerates discovery, and aligns with overall R&D strategy. Scientific Requirements & Solution Delivery: Translate complex scientific & technical into clear, documented, and prioritized data, digital & technology requirements and use cases. Oversee the end-to-end life-cycle management of technology solutions specific to Clinical Pharmacology & Development, including modelling & simulation platforms (eg. Certara Simcyp Simulator, InSilico Trials etc.), Pharmacovigilance (PV) & Safety Systems etc. AI/ML Strategy & Scientific Prioritization: Utilize AI/ML subject matter expertise to identify high-value AI/ML use cases across the Clinical Pharmacology & Development functions. Define the strategic prioritization framework for AI/ML projects, ensuring focus on initiatives with the highest impact. Oversee the process for monitoring & scientifically validating and benchmarking AI/ML models (both internal and external) to ensure their reliability and drive successful scientific adoption. Data Strategy, Governance & FAIR Principles: Drive the Clinical Pharmacology & Development Data Strategy, ensuring data generated both functions is FAIR (Findable, Accessible, Interoperable, Reusable) and is aligned to overall Global R&D Technology Solutions data & AI strategy. Design, develop & implement a strategy for all BeOne generated Clinical Pharmacology & Development data to be 'AI-ready’. Ensure Clinical Pharmacology & Development data governance alignment with BeOne Data Governance and enforce data governance, quality, and metadata standards within the Clinical Pharmacology & Development functions to ensure data integrity and reliability for critical decision-making. Vendor Management: Identify, evaluate, and manage strategic technology vendors who provide cutting-edge scientific software and / or AI/ML capabilities, as needed. GRDTS Leadership: Team Leadership & Talent Development: Lead, mentor, and manage a high-performing GRDTS team dedicated to the Clinical Pharmacology & Development functions. Foster a culture of innovation, accountability and drive professional development in areas like AI/ML, cloud computing, and advanced analytics. Data, Technology & AI/ML Infrastructure & Platform Development: Lead the design, implementation, management & maintenance of scalable Clinical Pharmacology & Development data, technology, AI/ML platform environments as needed. Ensure these platforms provide robust capabilities for data repository, management, analytics, ML/AI model training, version control, lineage tracking, and production deployment of models into Clinical Pharmacology & Development systems. Innovation & Digital Transformation: Manage an Innovation Pipeline or 'Proof of Concept' program for novel technologies, rapidly evaluating their potential value to Clinical Pharmacology & Development. Operational Excellence, Compliance & Governance: Ensure all Clinical Pharmacology & Development-related systems and data platforms adhere to relevant pharmaceutical industry regulations and internal GTS security policies. Liaise with computer system vendors, IT partners, audit, and compliance to coordinate system implementation and change activities Develop an organizational framework and operating model that support the current and future technology needs for Clinical Pharmacology & Development that comprises requirements management, solutioning, build, implementation, and administration (run) of global Clinical Pharmacology & Development platforms, master data, and system interfaces Ensure team is trained in and embeds CSV, compliance, and health authority requirements into operational activities. Manage the Clinical Pharmacology & Development technology portfolio's budget, resource allocation, and project prioritization process to maximize return on investment. Collaboration & Data Foundation: Act as the voice of Clinical Pharmacology & Development within the broader GTS organization, ensuring the domain's needs (HPC, large-scale storage) are prioritized. Collaborate with other business partners on standards and best practices. Lead and support Global Technology Solutions (GTS) initiatives to support its growth and maturity. Engage with peers to define, sponsor, and execute continuous improvements. Supervisory Responsibilities: Lead, mentor, and manage a high-performing GRDTS team dedicated to the Research function. Other Qualifications: 14+ years of professional experience in data, digital & information technology with direct oversight and experience in / for the Clinical Pharmacology & Development-related data & technologies in the Pharmaceutical, Biotechnology, and/or Medical Device industries 7+ years of proven leadership experience at a senior level, directing a team of multi-skilled direct reports and associate-level team members. 7+ years combined experience in design, deployment, support, and/or use of Clinical Pharmacology & Development function focused digital transformation of processes, platforms, systems, software, repositories including modelling & simulation platforms, Pharmacovigilance (PV) & Safety Systems etc. Strong experience in data & AI methods and technologies to support the Clinical Pharmacology & Development functions. Business relationship management acumen and demonstrable success as a change agent leading or contributing to significant transformational initiatives in organizations. Strong experience with software lifecycle methodologies, 21CFR Part 11 compliance, and GxP computer systems validation (CSV), ICH guidelines. Accomplished in building and development of people and teams, comfortable working with a broad cross section of people in direct and matrixed relationships Proficient in various project management disciplines (i.e., Agile, Scrum, Kanban, Lean etc.) Travel: Some travel expected as part of assigned duties Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Salary Range: $267,400.00 - $347,400.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com. BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 11,000 colleagues spans six continents. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn, X (formerly known as Twitter), Facebook and Instagram. For more information, please visit the link to explore job opportunities in China Mainland. China Mainland Job Posting At BeOne, how we work is just as important as the work we do. Below are our Values that determine the decisions we make and how we do things. Patients First Driving Excellence Bold Ingenuity Collaborative Spirit

Oversee clinical monitoring activities, manage CRA team performance, ensure compliance with regulations, and optimize trial processes. | Minimum 5 years in pharmaceutical or CRO industry, with 2+ years in people or project management, and a strong understanding of clinical trial processes and regulations. | BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. General Description: The Clinical Research Manager oversees clinical monitoring activities and the CRA team's performance to ensure they comply with ICH-GCP, local regulations, and company SOPs, and maintain quality across clinical trials. As a line manager, this role leads a team to achieve organizational goals and ensure high performance by providing guidance, support, and development opportunities while promoting a positive team culture. Essential Functions of the Job: • Team Resource Allocation & Performance - Allocate CRA resources and perform ongoing resource assessments to ensure a balanced workload for quality monitoring and to meet study deliverables. - Ensure CRAs have the required level of monitoring knowledge and skills to successfully perform required activities with high quality to meet study deliverables. - Is responsible for managing and addressing CRA performance and quality indicators in accordance with ICH-GCP, SOPs and local regulations. - Strengthen site relationships to enhance performance and uphold the company’s trial delivery reputation. • Quality and Compliance - Review monitoring quality and resolve issues to ensure compliance with regulatory guidelines, ICH-GCP Guidelines, and Good Clinical Practices. Effective September 01, 2025 - Support study/site milestone delivery in collaboration with cross-functional teams. - Responsible for execution of assessment visits and accompanied visits (where required) to assess ongoing CRA monitoring competency, identifying issues and developing resolution strategies. - Contribute to process optimization initiatives and manage risk escalation and resolution. - Support site audits/inspections/Site Compliance Visits (SCV) and ensure corrective action and follow-up for identified issues. • Expense Review and Management - Review and approve expenses related to CRA activities to ensure alignment with applicable policies and financially best local practices. - Identify opportunities for cost-saving and efficiency while maintaining quality and compliance standards. Supervisory Responsibilities: • Recruitment and Onboarding: Performs recruiting and hiring activities, along with onboarding new team members to ensure alignment with team objectives and culture. • Task Assignment: Assign tasks based on individual strengths and team objectives, ensuring optimal productivity. • Support and Resource Provision: Support team members by providing necessary resources to help them effectively perform their roles. • Communication and Collaboration: Encourage open communication and collaboration within the team and with other functions, including a point of contact for issue escalation and feedback where required. • Performance Evaluation: Conduct regular performance evaluations and provide constructive feedback to promote continuous improvement. • Mentoring and Development: Lead and mentor team members, fostering an environment of growth and development. • Issue Resolution: Address any personnel issues promptly and fairly to maintain a positive work environment. • Career Development Support: Support team members in identifying and pursuing professional development opportunities. Computer Skills: Proficient in Microsoft Word, Excel, PowerPoint and Outlook Other Qualifications: • Fluent in written and verbal English • Minimum 5 years of industry experience in the pharmaceutical or CRO or relevant field • Minimum 2 years of People management or project management experience in progressive clinical research within the biotech, pharmaceutical sector, CRO industry or relevant field is preferred Effective September 01, 2025 • Thorough understanding of the drug development process, including expert knowledge of international standards (ICH GCP) and health authority requirements • Understanding of all aspects of monitoring and trial execution, with previous experience as a CRA preferred • Excellent interpersonal skills, strong organizational and effective written and verbal communication skills. Demonstrated team leadership experience. Experience in Oncology is highly recommended. Travel: Be adaptable to business trips as required per business need; require valid driver’s license in applicable countries Education Required: Bachelor’s degree or higher in a scientific or healthcare discipline, and advanced degrees preferred. Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Salary Range: $118,600.00 - $158,600.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com. BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 11,000 colleagues spans six continents. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn, X (formerly known as Twitter), Facebook and Instagram. For more information, please visit the link to explore job opportunities in China Mainland. China Mainland Job Posting At BeOne, how we work is just as important as the work we do. Below are our Values that determine the decisions we make and how we do things. Patients First Driving Excellence Bold Ingenuity Collaborative Spirit

Lead and coordinate the U.S. Market Access department, developing strategic plans, collaborating across functions, and managing product commercialization and stakeholder engagement. | Extensive experience in pharmaceutical market access, leadership in cross-functional teams, and a strong understanding of healthcare landscape and commercialization. | BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. General Description: The Executive Director, Market Access Strategy, Evidence & Value will be a key leadership role and strategic leader within the U.S. Market Access department. The position is responsible for coordination across market access segments, department and cross functional collaborations with key internal stakeholders. The position will directly support the VP of Market Access and will help in the development and evolution of the market access strategic and tactical plan. The primary focus will be on market access strategic marketing, business insights, evidence generation and value messaging to help optimize in line and pipeline products across a broad array of market access stakeholders. Essential Functions: Partner with VP of Market Access to refine, enhance and evolve the market access strategic and tactical plan Support the VP Market Access to align the various department segment leaders, provide cross department and cross functional strategic and business insights internally Strategic partner to VP of Market Access regarding identification of industry trends, opportunities and challenges, providing cross segment, innovative, strategic recommendations and initiatives positioning BeOne as “best in market” market access department Lead and operate as the primary contact/liaison for market access regarding cross department collaborations and partnerships MA team leader for all new products, market access commercialization planning post early pipeline transition including distribution strategy/planning, department resourcing, reimbursement assessment/planning, National & Strategic accounts, payers and value and access planning Access, evaluate, advise, design and implement strategy/operations segment to assist and support the department needs Support and partner with VP of Market Access to constantly evaluate department performance and effectiveness, identify opportunities to optimize achieving KPI’s and maximizing results Present Market Access strategic updates, landscape assessments, department performances and ad hoc topics/projects to the CLT and leadership team Partner with VP of Market access to represent and lead segment annual budgeting, tracking spend, revising and enhancing processes and policies Triage requests and act as a liaison between the VP of Market Access and other segment leaders, and stakeholders to ensure consistent communication and involvement or decision-making at the proper time Collaborate with VP and segment leaders in the development of department goals and long-term operational plans Listen for and identify connection points and opportunities for agreement across organizations to bring the right stakeholders to the table and drive a coordinated approach Anticipate, identify and then facilitate resolution of issues between departments and across functional lines pertaining to projects, strategic priorities and team dynamics Drive consistent communication and collaboration within the Market Access function and across the organization Partner with field team leadership and team members on delivering key messages and identifying gaps and opportunities Establish and maintain a work environment that supports learning, respect, open communication, collaboration, integration, and teamwork Partner with VP of Market Access to oversee the design, organization and execution of leadership offsite events A trusted partner and experienced market access expert Strong understanding of biopharma Market Access, commercial functions and healthcare industry Excellent interpersonal communication skills Strong executive presence and exceptional presentation capabilities, ability to articulate complex, market access topics Judgement to surface critical business issues to the LT for discussion and decision Understands their role of "leading from behind" and leans into this Adaptable, strong listener, comfortable providing feedback Strong collaboration skills, with an ability to influence multiple stakeholders often without authority; build mutual trust, respect differences of culture and opinion, communicate openly and build consensus High emotional intelligence, relationship builder, empathetic, works well with different people types at all levels of the organization Excellent communication skills - clear verbal and written communicator, summarizes information succinctly, able to adapt communication to different audiences Outstanding time management and experience at performing in the context of a fast-paced biotech, multicultural, global organization, working across boundaries and leading through influence Strong project management skills - organized, disciplined, comfortable following up on actionable / holding people accountable, able to think ahead and catch problems before they arise Qualifications: Minimum of 10 years of related pharmaceutical market access experience with experience in market access, leadership and building cross functional collaborations Extensive, direct experience leading various market access functions including payer, patient support, distribution, national and strategic accounts, value and access Strong business acumen regarding market access commercialization, healthcare landscape and insights Previous experience planning, launching and commercializing new market access products Direct experience managing complex market access products in competitive marketplaces Excellent listening and organizational skills, ability to think strategically and execute tactically Excellent interpersonal, oral and written communication skills including ability to synthesize complex marketplace landscape dynamics, issues and opportunities Demonstrated track record of collaborating across organization to achieve target outcomes Ability to prioritize and manage multiple tasks and projects, and deliver effective results within defined timelines Education Required: Bachelor’s degree required, Master’s and/or other advanced degree preferred Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Salary Range: $283,700.00 - $363,700.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com. BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 11,000 colleagues spans six continents. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn, X (formerly known as Twitter), Facebook and Instagram. For more information, please visit the link to explore job opportunities in China Mainland. China Mainland Job Posting At BeOne, how we work is just as important as the work we do. Below are our Values that determine the decisions we make and how we do things. Patients First Driving Excellence Bold Ingenuity Collaborative Spirit

Leading safety strategies and oversight for a pharmaceutical franchise, ensuring regulatory compliance, and guiding safety data interpretation. | Requires MD with 10+ years in pharma/biotech, extensive pharmacovigilance experience, and leadership in global safety operations. | BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. The Executive Medical Director, Safety Franchise Area Lead will lead and oversee a team of Product Safety Physician Leads within the assigned franchise or disease area. This role is responsible for establishing strategic safety direction and ensuring consistent, high-quality execution of safety activities across all assigned molecules and medicines within the franchise. The Safety Franchise Area Lead has direct accountability for safety oversight of all compounds within the franchise or disease area and is responsible for shaping portfolio-level safety strategies, execution, and stakeholder engagement. This includes leading routine franchise- or disease area-wide safety activities, planning, and decision-making that require cross-functional coordination across multiple molecules and development programs. The Safety Franchise Area Lead represents Safety Science at the franchise committee and applicable governance forums, providing expert input on safety considerations to inform portfolio and development strategies. In addition, this role is expected to engage hands-on at the individual program level as needed and may directly serve as the Product Safety Lead for (a) specific program(s), providing direct safety leadership, expert guidance, and decision-making for specific programs through appropriate governance processes. Franchise/Disease Area Leadership Act as a safety technical reviewer for all relevant safety documents or clinical documents with safety content prepared by Product Safety Leads and supporting teams, providing strategic and medical leadership input. This includes but not limited to safety strategies and plans; Target Early Profile (TEP)/Target Product Profile (TPP), safety content of protocols; Investigator’s Brochure; Informed Consent Form; Safety Analysis Plan; clinical study reports; CCDS/product labels; Risk Management Plans; Summary of Clinical Safety and ISS; aggregate safety reports; Health Authority Request for Information/Queries; relevant safety communications (e.g., DIL/DHPC/DHCP letter), and scientific publications Evaluate the appropriateness of strategies to address safety issues and/or enquiries from internal and external stakeholders, review supporting data and drafted content, and manage communication or escalation in alignment with BeOne processes and standards Ensure a robust and independent safety position is established for all assets supported by the franchise/disease area, and that the impact of safety findings is systematically assessed through appropriate governance processes and stakeholder engagement with clear and appropriate medical interpretation of safety information Facilitate communication and functional alignment with the Safety Leadership Team and key functional partners Provide matrix leadership and drive consistent application of franchise-wide operational standards to maintain a robust safety support framework across all molecules and/or programs Lead routine franchise-level resource planning and utilization to ensure appropriate prioritization and coverage in line with business priorities as a direct/matrix manager Plan and coordinate the transition of assets across all phases of development and through the full product lifecycle, ensuring continuity of safety strategy, ongoing risk assessment, and consistent safety oversight from early development through post-marketing activities Accountable for overseeing and guiding the performance of Product Safety Leads, to ensure consistent delivery aligned with business strategies, required behaviors, quality standards, and defined processes Provide matrix leadership, mentoring, and strategic direction to Safety Science team members supporting the franchise/disease area Molecule-specific Contributions Governance Lead program-specific Safety Management Team meeting and/or provide oversight of all compounds within the franchise/disease area, ensuring accurate medical contextualization of safety data, quality presentation, and appropriate recommendation of actions across molecules/programs at SMT and Company Safety Committee (CSC) meetings Lead and/or oversee the communication of governance recommendations to clinical development/labeling /quality/other relevant stakeholders. Guide the development of content to address required actions, including the strategic implications and implementation across applicable molecules and programs Accountable for safety data content and provide strategic insights and medical leadership to Data Monitoring Committees (DMC)/Safety Monitoring Committees (SMC), including input on charters and participation in meetings as required across all molecules/programs within the franchise Issues Management Lead and manage escalation of potential issues to safety governance (SMT/CSC) or appropriate cross-functional governance, executes Crisis Management response plan, ensure internal notification and provide updates Lead safety issue/regulatory inquiry management, formulation of response strategy, comprehensive review and contextualization of data from all sources (e.g., CT, PM, non-clinical, literature, epidemiology, competitor safety profile labelling, etc.), risk management, and closure of recommendations, including the drafting, review, and approval of analysis/response documents Actively lead safety in regulatory interactions Guide and lead medical review of SAEs, provide immediate input to escalated cases, and determine and execute further escalation within BeOne as required per applicable processes Commercialization Support and Liaison with Other Functions Lead the development and execution of safety differentiation strategies for BeOne products, provide input into TPP, publications strategy (including review of abstract, manuscripts, and speaker presentations), contribute safety expertise to evaluation of potential in-licensing opportunities as requested Lead product liaison for BeOne functions (Legal, Bus Dev, Operations, Marketing, etc.), execute appropriate communication of safety data and interpretation to BeOne and external parties, globally, facilitates communication with country office medical directors as required Provide training to BeOne employees on product safety profiles/issues Trial Safety Support Accountable for safety data and responsible for providing guidance on safety endpoints, safety-related inclusion and exclusion criteria, schedule of assessment, and trial data capture; lead study and program-level data review and appropriate actions to address safety findings Accountable for defining the safety plan in protocols, the safety sections of the IB, ICF, and updates to trial documentation based on new safety data Actively develop the specification of anticipated safety-related statistical analyses for clinical trials, ensuring inclusion in the SAP with appropriate safety endpoints, analysis populations, and methodologies to support regulatory and program-level safety assessments Define safety data requirement and develop safety section of the clinical data management plan, supports the review and update of data management plan based on updates to integrated safety viewpoint during trial Accountable for the determination of safety data required for capture in CRFs during clinical trials, review and provide input to CRFs Lead the formulation safety criteria and review of study specific medical monitoring plans Accountable for the content of safety sections of the Development Safety Update Report (DSUR), including review and approval Participate in investigator meetings as needed, taking accountability for the product safety profile and all safety presentation content Developmental and Postmarketing Product Safety Monitoring and Surveillance Accountable for the development of Signal Detection Plan and analysis of SAEs by system, compound and TA to detect significant correlation/ causation Accountable for daily, weekly, and monthly review of SAEs and abnormal labs, protocol specific review of aggregate SAEs and specific analysis of aggregate CTDB (AE tables, shift tables, listings) Reviews and guides interpretation of safety findings as part of the monthly/quarterly signal detection review meeting and accountable for signal detection reports using internal and external data Accountable for output/summary report for inclusion into clinical, filing, and post-market reports Submission Filing Safety Support Proactively, reviews and interprets study safety data, supports Clinical Study Report narrative generation, leads the interpretation-based safety sections of reports, reviews draft report Accountable for drafting the safety sections of the Summary of Clinical Safety and ISS Leads 120-day update plans and activities Product Labeling Lead communication of CSC recommendations for labeling amendments, participates in Labeling Working Group meetings, leads communication of Safety outcomes to relevant stakeholders Contribute safety strategy and content for the development and update of Company core data sheet (CCDS) Provide safety insights to the development of Package Insert and Labeling Updates, develops labeling update impact summaries for use by RA, develops labeling prose text updates, based on internal aggregated reports Postmarketing Pharmacovigilance Actively leads PSUR/PBRER strategy, determines content and oversight, contributes to authoring of relevant sections and review of PSURs/PBRERs Actively leads the scope, strategy, and content of responses to HA assessment reports, contributes to authoring of relevant sections, reviews and manages approval of PSUR/PBRER responses to HAs Actively leads the definition of Risk Management Plan (RMP) drivers & content, reviews core RMP & local RMPs (or REMS) and leads execution of RMP elements, documentation of evidence of RMP execution, evaluates potential risks for evidence of risk confirmation and leads recommendations for RMP/REMS update Actively leads the development of safety Post Approval Commitments (PAC) proposals, facilitates the design of PAC proposed safety study, executes PAC studies Leads and manages the definition of events of interest, defines case follow-up needs Accountable for development and implementation of product launch plans Accountable for development of a publication plan, contributes to draft manuscripts/abstracts Contributes to and promotes the development of a global Pharmacoepidemiology (PE) strategy Process Excellence Actively leads the evaluation of current processes and assesses alignment with regulatory expectations, guidelines, mandates for regulatory inspections Actively leads and maintains an environment of continuous improvement within the team and contributes to continuous improvement initiatives across GPS Supervisory Responsibilities: Manage one or more franchises, including direct supervision of the Product Safety Physician Leads or other Safety Science team members supporting the respective franchise/disease area. Computer Skills: Intermediate knowledge working with a safety database for retrieval of safety information; Advanced knowledge of MedDRA; MS Office Suite: Advanced application capability with Excel, PowerPoint, and Word. Familiarity with data mining tools and exploratory analyses tools such as Spotfire. Other Qualifications: Prior matrix management team experience Prior experience as a product safety physician Pharmaceutical product development experience, including individual study design and filing plans Experienced in global regulatory requirements for pharmacovigilance Appropriate experience with Regulatory Agency and KOL interactions Travel: Less than 10% Education Required: MD (or internationally recognized equivalent) plus accredited residency, with 10+ years pharmaceutical/biotechnology industry experience in Clinical Research, Clinical Development with at least 6 years in pharmacovigilance. Accredited fellowship with 1-year clinical experience with patients in a relevant therapeutic area specialty, with significant knowledge of general medicine is preferred Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Salary Range: $328,000.00 - $408,000.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com. BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 11,000 colleagues spans six continents. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn, X (formerly known as Twitter), Facebook and Instagram. For more information, please visit the link to explore job opportunities in China Mainland. China Mainland Job Posting At BeOne, how we work is just as important as the work we do. Below are our Values that determine the decisions we make and how we do things. Patients First Driving Excellence Bold Ingenuity Collaborative Spirit

Lead and manage global oncology clinical development projects, ensuring alignment with strategic goals, process optimization, and stakeholder communication. | Extensive experience in drug development or related industry, leadership in multicultural/global environments, and project management expertise, preferably with PMP certification. | BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. General Description: Lead and/or mentor the program management team for oncology clinical development lifecycle management. Develop and lead global product development strategies. Establish clear processes for team management and communication. Drive strategic team decision-making and delivery of team goals and objectives. Lead process improvement initiatives and optimize team efficiency, quality and performance. Collaborate with teams to deliver on commitments to the organization and to patients. Essential Functions of the job: Plan and execute projects in accordance with the global clinical development strategy. Facilitate alignment with key stakeholders and ensure communication across project teams. Develop, validate, and maintain project schedules within the enterprise project system. Plan, track, and manage project milestones, dependencies, and critical path. Lead and facilitate team planning sessions: develop team charter, define project scope, and ensure global cross-functional alignment. Implement good project and risk management practices. Manage process for project budget governance and oversight within oncology. Liaise with internal and external collaborators to deliver high quality work product, presentations, etc. Provide internal project management support to core and sub teams, as necessary. Coordinate team meeting schedules, prepare agendas and minutes, track action items and progress reports according to project management best practices. Lead process improvement initiatives, e.g., budget change control, program management dashboards and reports, risk management, etc. Assume additional responsibilities and leadership that are commensurate with experience and expertise such as independently providing alliance management for drug development partners, independently leading oversight steering committees. Required Experience: Bachelor’s degree with 10 + years’ overall experience in drug development or commercial within academia, consulting, pharmaceutical or biotechnology industry. Master’s Degree with 7 + years’ overall experience in drug development or commercial within academia, consulting, pharmaceutical or biotechnology industry. 3 + years in leadership roles as leader in a multicultural & international (global) portfolio environment is a plus Supervisory Responsibilities: TBD Computer Skills: Efficient in Microsoft Word, Excel, Project, and Outlook Other Qualifications: PMP certification a plus Travel: As Needed Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Salary Range: $178,700.00 - $238,700.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com. BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 11,000 colleagues spans six continents. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn, X (formerly known as Twitter), Facebook and Instagram. For more information, please visit the link to explore job opportunities in China Mainland. China Mainland Job Posting At BeOne, how we work is just as important as the work we do. Below are our Values that determine the decisions we make and how we do things. Patients First Driving Excellence Bold Ingenuity Collaborative Spirit

Oversee enterprise-wide performance, continuous improvement, governance, and change enablement across technology portfolios. | Extensive leadership in enterprise process excellence, experience with digital technology, and stakeholder management in regulated industries. | BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. General Description: The Executive Director, Operational Strategy Enablement is a senior leader responsible for enterprise-wide performance and value delivery across the technology portfolio. The role oversees three integrated pillars: (1) Process and Service Excellence (PSE) — continuous improvement of delivery and run operations using Lean/Agile, DevOps/SRE, ITIL 4, automation, and data-driven management; (2) Program and Portfolio Governance (PPG) outcomes-driven prioritization and governance of programs and projects across product, platform, infrastructure, security, and enterprise systems; (3) Adoption & Change Enablement (ACE) — human-centered change, training, and communications that ensure new platforms, processes, and tools are adopted and deliver measurable benefits. This leader partners closely with Enterprise Architecture, Global Business Partners, Infrastructure & Operations, Cybersecurity, Data/Analytics, and Finance/FinOps to improve reliability, speed, cost efficiency, risk posture, and customer experience—embedding excellence into the operating model and culture. Essential Functions of the Job: Process and Service Excellence (PSE) Continuous Improvement: Lead Lean/Six Sigma value stream mapping and kaizen across ideation → build → deploy → run → improve; remove bottlenecks and waste. Drive continuous improvement across IT operations using Lean, Six Sigma, and Agile methodologies. Establish metrics and KPIs to monitor performance, cost-efficiency, and service quality. Foster a culture of accountability, innovation, and customer-centricity. Operating Mechanisms: Stand up daily/weekly management routines, executive ops reviews, and OKR cadences; deliver dashboards linking operational metrics to business outcomes. Program and Portfolio Governance Oversee enterprise-wide project delivery through standardized frameworks and gated governance models. Align technology investments with strategic priorities and business outcomes. Collaborate with cross-functional teams to ensure timely execution and measurable value delivery. Adoption and Change Enablement Change Strategy: Establish OCM standards integrated from inception through sustainment for process and technology changes. Lead stakeholder analysis, readiness and impact assessments across engineers, SREs, platform teams, ops, and business partners; define role-based change journeys. Orchestrate multi-channel communications; deliver targeted enablement (hands-on labs, train-the-trainer, office hours); coordinate change agent networks. Define adoption KPIs (utilization, proficiency, satisfaction, support ticket deflection); implement reinforcement mechanisms and benefits sustainment plans. Embed OCM into Agile frameworks and portfolio governance to ensure behavioral change keeps pace with technology delivery. Education Required: Bachelor’s Degree in Business Administration, Computer Science, Engineering or equivalent (Masters degree preferred) Qualifications: BA?BS with 14+ years of progressive leadership in enterprise process excellence with a focus on digital technology. Lean Six Sigma Black Belt Proven experience in regulated industries (e.g., pharma, healthcare, finance) preferred. Strong business acumen and ability to translate strategy into execution. Exceptional communication, stakeholder management, and team-building skills. Travel: 15% or less Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Salary Range: $267,400.00 - $347,400.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com. BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 11,000 colleagues spans six continents. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn, X (formerly known as Twitter), Facebook and Instagram. For more information, please visit the link to explore job opportunities in China Mainland. China Mainland Job Posting At BeOne, how we work is just as important as the work we do. Below are our Values that determine the decisions we make and how we do things. Patients First Driving Excellence Bold Ingenuity Collaborative Spirit

Assist in designing, planning, and executing learning and development projects, managing LMS platforms, and supporting training sessions. | Currently pursuing a Bachelor's or Master's degree in a related field, with strong organizational, communication, and computer skills. | BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. Internship program dates: June 8 - August 21, 2026 Education Required: Rising junior, rising senior or graduate student working toward a Bachelor's or Master’s degree in Human Resources, Industrial-Organizational Psychology, Business Administration, or related field in progress. General Description/Scope of Responsibilities (Internship): BeOne’s Global Talent Development team focuses on the organization’s learning and development initiatives at all levels to drive organizational performance. In this role, the Talent Development Intern will have the opportunity to support two major projects: Development Week and BeOne’s Learning Month. Development Week is an organizational campaign highlighting the importance of continuous learning and personal growth at BeOne. Different functions within the organization will host virtual sessions in the areas of personal, professional, and technical development. BeOne’s virtual learning month will be the business’s opportunity to share function news, information, and updates with a global audience. and onboard users onto our new learning platforms. This individual will be responsible for assisting with designing, planning, coordinating and execution of both projects. The projects will provide valuable insight and exposure working globally, cross-functionally and within HR. In addition to the assigned projects, interns are given the opportunity to participate in activities that encourage networking with peers, managers, and employees. Essential Functions of the job: Learn to manage the administration of Development Week activities in our LMS, coordinating needs from various regions. Assist in Learning & Development Program Coordination Support the planning, scheduling, and execution of training sessions, workshops, and webinars. Help manage LMS (Learning Management System) platforms, including uploading content and tracking participation. Coordinate logistics for training sessions, such as booking rooms, sending invitations, and preparing materials. Assist in virtual and in-person training sessions as needed by facilitators. Support Employee Training & Development Initiatives Assist in the creation and updating of learning materials, presentations, and job aids. Help curate learning resources from internal and external sources. Monitor and analyze training attendance, completion rates, and feedback to assess program effectiveness. Gather and Analyze data for Talent Development Metrics Assist in collecting and analyzing colleague feedback and training evaluations to help identify areas for improvement. Provide General Administrative Support Maintain accurate records of training sessions, certifications, and talent development initiatives. Organize and update Talent Development learning databases, SharePoint sites, and LMS. Other duties as assigned. Computer Skills: Strong knowledge of MS Office Applications (Word, Excel, PowerPoint, Forms). Expertise with Zoom, MS Teams, Outlook, and other technology platforms to help produce and support virtual trainings. Computer and data literacy Familiarity with data analysis and reporting. Comfort in using Cognota a plus. Other Qualifications: Ability to communicate professionally and succinctly with all levels of management via email, Teams, and Zoom. Excellent written and oral communication skills. Strong organizational and project management skills. Detail-oriented, a self-starter, and be comfortable with broad responsibilities and competing priorities in an entrepreneurial, fast-paced, corporate environment. Flexibility to participate in occasional meetings outside of normal business hours to collaborate with our China colleagues and our European colleagues. Travel: n/a Pay Rates: Bachelors: $27/hour USD Masters: $30/hour USD Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Salary Range: $ - $ per hour BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com. BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 11,000 colleagues spans six continents. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn, X (formerly known as Twitter), Facebook and Instagram. For more information, please visit the link to explore job opportunities in China Mainland. China Mainland Job Posting At BeOne, how we work is just as important as the work we do. Below are our Values that determine the decisions we make and how we do things. Patients First Driving Excellence Bold Ingenuity Collaborative Spirit

Support pipeline development and external collaborations in oncology, develop regional strategies, and build scientific relationships. | Requires clinical/scientific degree and experience in oncology or related fields, with regional HCP relationships and research experience. | BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. This role is similar to the Senior Medical Science Liaison role and is an individual contributor role. The Senior Field Medical Director (FMD) will support BeOne Pre-Clinical and Clinical pipeline development by coordinating external collaborations, research endeavors with heath care providers and external academicians while ensuring internal partnership across the organization. The candidate will report to the Senior Regional Director, Hematology, within Medical Affairs. As a leader in the organization, the incumbent will be accountable to develop regional strategies to support enduring and compliant relationships with Opinion Leaders, Research Collaborators & Key Organizations in support of BeOne pipeline development (Solid Tumor or Hematology). This position will require pre-launch and post-launch Medical Affairs support for solid tumor and/or hematology pipeline development, focusing on solid tumors. Specifically, the incumbent will work closely with internal colleagues in medical affairs, clinical development, program leadership, clinical operations, legal, compliance, new product planning, safety/pharmacovigilance, molecular diagnostics, marketing, sales and translational research. The incumbent will play a key role in the establishment of BeOne as a valued collaborator and best-in-class biopharmaceutical company. Please note the individual must live within the Territory which includes: Virginia, North Carolina and South Carolina. Essential Functions: • Work with Cross-functional teams to develop robust territory plans that impact and inform HCPs leading to improved patient outcomes • Establish and maintain scientifically credible peer-to-peer scientific relationships with national & regional opinion leaders in addition to other healthcare providers • Facilitate & monitor strategic partnerships with scientific/clinical experts and serve as an enterprise-level point of contact with organizations including but not limited to - • Guideline development • Cooperative groups • Other (National Cancer institutions) • Serve as an internal resource of clinical and scientific information from medical interactions • Provide impactful feedback/information to internal stakeholders on emerging clinical and scientific trends • Nominate sites to Clinical Operations to participate in clinical research • Contribute to or perform therapeutic area/indication research and competitor analysis • Assist in the development and execution of clinically relevant regional medical meetings (e.g., advisory boards, consultant, and investigator meetings), as requested • Identification and verification of investigators and sites for company-sponsored clinical trials • Serve as a liaison for the submission and review of Investigator Sponsored Research proposals • Support major and regional congresses engaging thought leaders • May work cross-functionality to provide balanced and accurate information to top regional formulary decision makers and/or P&T committee members • Build strong relationships with internal experts. • Identify continuous process improvement opportunities. • Develop, track, execute and report on goals and objectives. • Support Medical Affairs budget planning and management. • Be accountable for compliant business practices. Education Required: • MD, PharmD., PhD, or DO, OR a NP, PA, Master’s Degree within a clinical and/or scientific profession is required Required Qualifications: • MD, PharmD., PhD, or DO, within a clinical and/or scientific profession with 5 + years’ clinical experience and/or success within other biotech/pharmaceutical companies OR a NP, PA, Master’s Degree within a clinical and/or scientific profession with 7 + years’ clinical experience and/or success within other biotech/pharmaceutical companies. • Clinical oncology experience in hematology/oncology; candidates with exceptional experience in other therapeutic areas may be considered if they demonstrated clear potential to apply their existing skills to oncology • Relationships with relevant HCPs in region • High level of communication (written and verbal), interpersonal, organizational, and cross functional collaboration skills • Flexibility to work with colleagues in a global setting • Able to engage in work-related travel approximately 60-70% • Impactful verbal and written communication skills • Ability to effectively collaborate in a dynamic environment • Strong comprehension of disease states, and knowledge of differential algorithms for treatment decisions and experience in disease states of interest to BeOne • An expert understanding of the health care delivery system, including the managed care arena and its impact on patient care, regional medical care and the pharmaceutical industry • Ability to identify the unmet medical, educational, and research needs at a local & regional level in the medical community • Ability to interpret key scientific data and translate the findings to meet educational and research needs in order to affect corporate research strategic activities/decisions • Understanding of the design and execution of research studies and strategic implications • Exhibits high degree of emotional intelligence and appreciation of diversity and multiculturalism • Designs and/or leads training initiatives and best practices • Proven ability to drive results at a high level of quality as a strategic and creative thinker • Demonstrates ability to deal with ambiguity and thrive in an ever-changing environment • Strong project management skills with demonstrated ability to manage projects and/or colleagues in successful implementation of business-critical projects • Strong time management & organizational skills Supervisory Responsibilities: • No direct reports Computer Skills: • PC literacy required; MSOffice skills (Outlook, Word, Excel, PowerPoint) Travel: • Work related travel approximately 60-70% Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. • Fosters Teamwork • Provides and Solicits Honest and Actionable Feedback • Self-Awareness • Acts Inclusively • Demonstrates Initiative • Entrepreneurial Mindset • Continuous Learning • Embraces Change • Results-Oriented • Analytical Thinking/Data Analysis • Financial Excellence • Communicates with Clarity Salary Range: $227,300.00 - $297,300.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com .

Support and oversee clinical development programs, including study design, data analysis, and regulatory documentation, in collaboration with cross-functional teams. | Requires MD or DO with at least 3 years of oncology clinical development experience, including involvement in all trial stages, especially lung cancer. | BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. Reporting to the Clinical Development Lead, Biotech Unit (BU), the position is a member of BU and contributes to clinical development strategy and supports successful execution of clinical development programs in BU. Leveraging deep therapeutic and functional area expertise, the incumbent will play a key role in medical monitoring for pivotal stage studies, will be accountable to jointly develop clinical program strategy and help assure that activities are executed within expected scope, budget and timelines. The incumbent will work closely with colleagues in clinical development, program leadership, biometrics, clinical operations, safety/pharmacovigilance, regulatory, molecular diagnostics, and translational research to ensure successful deliveries by study team. Essential Functions of the Job: Facilitate generation of, author, update, and/or review key documents, including, but not limited to: Protocol concepts, synopses, protocols, and amendments o Informed consent documents; Investigator Brochures o Clinical study reports; Abstracts, posters and manuscripts o Clinical sections of INDs (and equivalent applications), NDAs (and equivalent applications), Annual Reports, and Developmental Safety Update Reports; Clinical sections of Health Authority Briefing Documents, Orphan Drug applications, and annual reports; Risks / benefits analysis for applicable documents; Clinical Development Plans. Partner with clinical operations and other functional areas for the successful implementation and execution of clinical studies. Provide scientific expertise for selection of investigator and vendors. Train BeOne colleagues, CRO staff, and study site staff on the therapeutic area, molecule, and/or clinical protocol. Provide scientific and medical support throughout conduct of a clinical trial; respond to clinical questions from sites, IRBs/IECs, Health Authorities, and CRO’s. Review, query, and analyze clinical trial data. Interpret, and present clinical trial data both internally and externally. Represent a clinical study or development program on one or more teams or subteams. Create clinical study or program-related slide decks for internal and external use. Build and maintain opinion leader/investigator networks; organize and present at key opinion leader advisory boards and investigator meetings. Contribute to or perform therapeutic area/indication research and competitor analysis. Build strong relationships with internal experts. Identify continuous process improvement opportunities. Identify incremental organizational resource needs – staff, budget, and systems. Develop, track, execute and report on goals and objectives. Support budget planning and management. Be accountable for compliant business practices. Basic requirement and experience: 5 plus years of experience and success within other biotech/pharmaceutical companies. MD or DO or international equivalent degree required. Previous participation in a clinical development program is essential, including involvement in all stages of clinical trials (i.e. from start up to study report), ideally having taken at least one study through from start to finish in a clinical development role. Minimum 3 years relevant work experience in oncology clinical development. Experience in conducting lung Cancer clinical trials strongly preferred. Expert understanding of global clinical study design and drug development process from discovery to registration and post-marketing. High level of communication (written and verbal), interpersonal, organizational, and cross functional collaboration skills. Knowledge of GCP and ICH Guidelines Flexibility to work with colleagues in a global setting. Able to engage in work-related travel approximately 25%. Strategic leader with demonstrated success building, managing and developing individuals and teams is preferred. Experience with the development and support of related SOPs and policies is expected. Knowledge of industry standard Clinical Development IT solutions expected. Entrepreneurship & creativity: · Have the ambition and passion to drive value and impact with a “can-do” attitude, willing to take calculated risk · Adopt an open and creative mindset to pilot new concepts and overcome challenges · High learning agility Strategic thinking: · Support strategic clinical development within Biotech Unit; integrate business case, mitigate risks and manage resources Adaptability: · Able to adapt to changes in the work environment. Manages competing demands. Changes approach or method to best fit the situation. Able to deal with frequent change, delays, or unexpected events. Cross-functional knowledge & expertise: · In-depth medical knowledge to drive operational excellence · Sufficient experience and ability to work in an environment that requires seamless cross-function collaboration and handling complexity Critical Competencies & Experience: · Proven ability to effectively work in a cross-region, cross-function matrix; able to work effectively in diverse cultures, showing aptitude in modifying style · Business acumen - understand unmet market needs; provide clear path to win; demonstrated track record in driving innovation through to the global commercialization of assets · Able to effectively communicate at multiple levels of the organization Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Salary Range: $249,800.00 - $309,800.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com. BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 11,000 colleagues spans six continents. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn, X (formerly known as Twitter), Facebook and Instagram. For more information, please visit the link to explore job opportunities in China Mainland. China Mainland Job Posting At BeOne, how we work is just as important as the work we do. Below are our Values that determine the decisions we make and how we do things. Patients First Driving Excellence Bold Ingenuity Collaborative Spirit