Alnylam

Oversee global product communications, develop strategic campaigns, and manage cross-functional teams to support biotech/pharma products. | Requires 15-20 years in biotech/pharma communications, proven campaign development, storytelling skills, and experience managing complex projects and teams. | Overview Reporting to the Chief Corporate Communications Officer, this role will oversee our product communications function encompassing 4 globally marketed brands, and 3 late-stage product candidates. This role's primary responsibility will be to serve as the communications head for our leading TTR franchise including both our marketed products for ONPATTRO and AMVUTTRA (80%), while also overseeing communications for the rare and late-stage pipeline assets. This role will spearhead the development and execution of clinical data and regulatory milestones; congress and publication communications; scientific platform communications for lay audiences; unbranded awareness campaigns; and executive thought leadership campaigns. The Senior Director also oversee a team of three product communications professionals. A successful candidate will be a dynamic, experienced with a proven ability to effectively manage complex projects, work collaboratively with stakeholders and across functions, effectively network across the organization and communicate with senior leaders all within a fast-moving environment. Key Responsibilities • Develop and manage comprehensive global external communications strategy that advances business goals for the franchise. • Create and execute branded and unbranded disease state education campaigns. • Actively monitor the competitive landscape, ensure response readiness, and adapt communications strategies accordingly. • Drive the product and franchise strategy focusing specifically where communications can deliver value with clear and specific tactics. • Work cross-functionally to ensure alignment with brand strategies (commercial, medical, market access, communications, HEOR, R&D, etc.) • Support internal communications for the US TTR leadership team. • Working together with international to ensure consistency. • Oversee day-to-day management of Communications agency, including budget oversight • Ability to think creatively and strategically to develop awareness campaigns and mobilize action Qualifications • Bachelor's degree in related field, advanced degree preferred. • 15-20 years of experience required, preferably in biotech, pharmaceuticals, or healthcare. • Proven experience crafting strategic campaigns, editorial content, and development of thought leadership platforms. • Superior storytelling, writing and editing skills; strong oral communications skills and ability to convey complex ideas • Digital and social media domain experience specifically in engaging audiences, with the ability to deliver innovative approaches and plans within this growing and important space. • Ability to link communications plans and activities to business results. • High levels of tact, passion for the employee experience, commitment, curiosity, fresh thinking, flexibility and a global perspective. • Ability to work independently and use sound judgment in decision-making, including setting and managing priorities and meeting competing deadlines. • Sound judgment and ability to maintain confidentiality. • Comfortable with accepting feedback and adapting to deliver the desired product. • Ability to interact with all levels of the company top to bottom, including most senior company management. • Meticulous attention to detail and commitment to high quality and timely work product. • Strong project management skills preferred. Experience managing vendors to execute on consulting work is preferred. #LI-LN1 About Alnylam: Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by "interfering" with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality. Our culture: Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we've been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as one of Science Magazine's Top Biopharma Employers, one of America's Most Responsible Companies for 2024 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK - among others. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.

Lead and execute U.S. medical strategy, ensure cross-functional alignment, and oversee medical excellence initiatives. | Requires advanced scientific degree, extensive Medical Affairs leadership experience, and proven ability to operate in complex, matrixed organizations. | The Director, US Medical Strategy and Excellence is a senior leadership role responsible for shaping and driving the strategic medical planning process across the U.S. TTR Medical Affairs organization. This role serves as a core member of the U.S. Medical Leadership Team and plays a critical role in ensuring strong alignment across U.S. Medical, Commercial, Global Medical Excellence, and Analytics and Insights (CC&I). The Director will lead U.S. medical excellence initiatives, advance key medical capabilities, and design and execute pilots that elevate how Medical Affairs delivers evidence-based, patient-centric impact. This role requires both strategic vision and operational rigor, with accountability for end-to-end execution of priority initiatives. Key Responsibilities Medical Strategy and Planning • Lead the U.S. Medical strategic planning process, including annual and multi-year medical plans aligned to brand strategy and enterprise priorities • Translate global medical strategy into U.S.-specific plans that are actionable, measurable, and scalablePartner closely with U.S. Medical leadership to ensure strategic priorities are clearly defined, resourced, and executed Medical Excellence and Capabilities • Lead U.S. Medical Excellence, including the design, implementation, and continuous improvement of medical capabilities, processes, and ways of working • Identify, pilot, and scale innovative approaches that enhance scientific exchange, insight generation, and medical impactEnsure alignment with Global Medical Excellence frameworks while tailoring execution to U.S. needs Cross-Functional Alignment • Serve as a key integrator across U.S. Medical, U.S. Commercial, Global Medical, and CC&I to ensure alignment on priorities, insights, and execution • Partner with CC&I to operationalize analytics, dashboards, and insights that inform strategy, measure impact, and drive decision-makingEnsure medical insights are systematically captured, synthesized, and shared to inform broader TTR strategy Execution and Governance • Own end-to-end execution of key U.S. Medical initiatives, from strategy through implementation and impact assessment • Establish clear governance, milestones, and accountability to ensure consistent delivery of high-priority programsMonitor progress, identify risks, and course-correct as needed to ensure excellence in execution Leadership and Influence • Act as a core member of the U.S. Medical Leadership Team, contributing to enterprise-level thinking and decision-making • Influence without authority across matrixed teams and stakeholdersModel a culture of accountability, rigor, collaboration, and continuous improvement Qualifications and Experience Required • Advanced degree required (PharmD, MD, PhD, or equivalent scientific degree) • Significant experience in Medical Affairs with demonstrated leadership in strategy, planning, and execution • Proven ability to operate effectively in complex, matrixed organizationsStrong strategic thinking combined with operational discipline and follow-through Preferred / Ideal Candidate Profile • Experience spanning pharmaceutical, medical technology, and biotechnology organizations • Prior experience in in-house Medical Director roles with accountability for medical strategy and execution • Direct experience in Field Medical roles, including MSL positions, with strong understanding of scientific exchange and insight generation • Experience leading Field Medical teams or Field Medical Excellence functions • Demonstrated success partnering with commercial, global medical, and analytics teamsStrong executive presence, communication skills, and ability to influence senior stakeholders Core Competencies • Strategic medical leadership • Medical excellence and capability building • Cross-functional integration and alignment • Analytics-driven decision-making • End-to-end execution and accountabilityTalent development and leadership influence U.S. Pay Range $208,300.00 - $281,800.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.