SAB

Compensation

Full Description

The Senior Director Immunology will lead discovery, preclinical development, and clinical translation of a novel multi-specific immunotherapy platform for complex autoimmune diseases. The incumbent will be a key participant in shaping translational strategy, driving biomarker innovation, overseeing assay development and immunophenotyping to support clinical decision-making and pipeline advancement. The role requires deep scientific expertise, vision and proven success advancing immunology-focused therapeutics in an industry setting. The Senior Director Immunology will also represent SAB at industry conferences and to other stakeholders, including investors and industry analysts. Duties and Responsibilities (Include but are not limited to): Oversee the design, execution, and validation of biomarker discovery, flow-based immunophenotyping, and patient-stratification assays for clinical trials. Direct experimental planning and data analysis, ensuring high-quality data interpretation, reporting, and communication to internal stakeholders and governance bodies. Partner with translational, clinical, regulatory, and development teams to integrate biomarker and assay strategies into protocols, regulatory documents, and clinical plans. Provide strategic leadership across Research and Translational Immunology, guiding disease biology insights, mechanism-of-action studies, and biomarker-enabled clinical strategies. Participate in translational and biomarker planning for discovery through clinical stages, including immunophenotyping, pharmacodynamic analyses, and molecular/cellular profiling. Manage and collaborate with CROs, external vendors, and academic partners to support assay development, method innovation, and data generation. Foster an excellent research environment, supporting lab-based teams in culture, collaboration, operations, and safety. Represent Translational Science and Immunology internally and externally, presenting scientific findings and program progress. This includes presenting to investors, analysts and at industry conferences. Identify and pilot innovative technologies to enhance translational science and immunotherapy development. Ensure compliance with global regulatory standards (FDA/CBER, EMA, MHRA, TGA) and maintain awareness of scientific and technical advancements relevant to autoimmune drug development. Supervisory Responsibilities: This position will have supervisory responsibilities. Education/Experience/Skills: PhD with 10+ years’ experience in Immunology or related field, with biotech/pharma industry experience required. Deep expertise in immunology, T-cell biology, autoimmune mechanisms, and therapeutic antibodies. Proven proficiency in clinical immunophenotyping, particularly advanced flow cytometry. Strong record of accomplishment in advancing immunology-focused therapeutics and leading translational/biomarker initiatives. Experience managing laboratory scientists and analytical teams. Skilled in molecular and cellular assay development within industry settings. Familiarity with global regulatory pathways (FDA, EMA, MHRA, TGA). Highly collaborative, innovative, with strong written and spoken communication skills and ability to lead in a matrixed, distributed environment. High level of emotional intelligence and the demonstrated ability to be an effective listener with strong diplomacy and presentation skills. Previous experience meeting with and presenting to internal and external stakeholders to include, but not limited to BOD, investors, analysts and at industry conferences. Physical Demands: While performing the duties of this job, the employee is regularly required to walk, stand, and sit. The employee must regularly lift and/or move up to 10 pounds. Working Environment and Travel: Normal home office working conditions. Travel to Sioux Falls location on a regular cadence per business demands. Periodic travel for work related activities, including travel for conferences, conventions, congresses, scientific presentations or other company related activities is required. This may include domestic and/or international travel. Ability to work extended hours include evenings and weekends based on business demands. ADA: The employer will make reasonable accommodations in compliance with the Americans with Disabilities Act of 1990. SAB BIO is an Equal Opportunity Employer and prohibits discrimination and harassment of any kind. SAB BIO is committed to the principle of equal employment opportunity for all employees and does not discriminate based on race, religion, color, sex, gender identify, sexual orientation, age, non-disqualifying physical or mental disability, national origin, veteran status or any other legally protected status. EOE/AA/Vets