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MT

Montai Therapeutics

via Greenhouse

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Director, Clinical Program Management

Cambridge, Massachusetts
Full-time
Posted 12/9/2025
Direct Apply
Key Skills:
Program Management
Risk Management
Cross-functional Team Coordination
Biopharmaceutical Development Knowledge
Microsoft Project and SharePoint
Communication and Facilitation
Budget and Forecast Tracking

Compensation

Salary Range

$90K - 130K a year

Responsibilities

Manage and coordinate preclinical and clinical development programs to ensure timely delivery of milestones, risk mitigation, and cross-functional team alignment.

Requirements

Bachelor's degree in life sciences or related field, 3+ years in biopharmaceutical industry, 2+ years program management experience in pharmaceutical preclinical/clinical development, strong communication and analytical skills.

Full Description

What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability? Montai Therapeutics is a privately held, biotechnology company focused on harnessing AI to decode untapped diverse chemistry to develop breakthrough oral medicines that can address persistent unmet needs in chronic disease. With our CONECTA™ platform, Montai has built the world’s leading foundation models for decoding the complex language between nature’s bioactive chemistry and human biology – supercharging the drug discovery process with unprecedented optionality and predictability. The company has curated and annotated a collection of over 1B Anthromolecules™ and Anthrologs™, which are derived from molecules humans have chronically consumed in food, supplements and herbal medicines. This has enabled efficient access to chemistry with vast untapped structural diversity and the potential to selectively and precisely modulate complex biology. Montai is rapidly advancing a pipeline of first-in-class oral medicines for validated biological pathways in inflammation and immunology – focused on biologic replacements and historically difficult to drug transcription factors. Position Summary We are looking for an experienced Preclinical development Program Manager to provide critical support to preclinical/clinical development cross-functional program teams to drive the delivery of program goals. The position will work collaboratively with the program leads, teams, and functional area leads in a fast-paced and exciting environment at the heart of ensuring planning and achievement of our critical corporate goals. This role is focused on enabling teams to advance therapeutic programs from development candidates to First-in-human studies and beyond. This is an exciting and visible role for a highly qualified and motivated individual. The Program Manager is responsible to plan, execute, manage risk, and manage critical paths according to strict deadlines and within budget. This includes engaging resources and coordinating the efforts of team members, third-party organizations where appropriate, and internal stakeholders to deliver program goals according to plan. Accountable to create program team governance to engage cross functional accountability of costs, schedules, scope, resources and track risks of programs and multiple integrated programs. Key Responsibilities will include, but not limited to the following: Support Program Lead to develop and foster productive cross-company relationships to develop, maintain and execute integrated program plans to identify/communicate interdependencies as well as critical path activities for the programs: Analyze program risks and identify impact while developing mitigation strategies, Identify and manage critical path, ensure appropriate program level definition across all stake holders and manage the program from concept to commercialization Monitor the overall progression of portfolio, including progress reports, milestones, key risks to achieving as well as key throughput and cost metrics Creates and executes program work plans and revises as appropriate to meet changing needs and requirements. Mitigates team conflict and communication problems. Motivates team to work together in the most efficient manner. Leverages program management tools to assist in the development of and adherence to established milestones and report status. Own and create appropriate levels of governance to ensure alignment and clear objectives Leads post-project reviews, identify root causes, distill key learnings, and ensure actionable recommendations are implemented and communicated across the program team. Work with Finance to implement and track program budget and forecasts, assist with operational and team meetings and other activities. Act as the source for information regarding the overall progression of the portfolio, milestone achievements, and risk monitoring Support strategic initiatives that enable teams to improve productivity and maintain focus on being an agile organization. Qualifications Bachelor’s degree in life sciences or related field. Advanced degree (MS, PhD or MBA) and/or PMP Certification preferred. A minimum of 3+ years of experience in the biopharmaceutical/pharmaceutical industry. Previous experience in immunological therapeutics and small molecules preferred. A minimum of 2+ years of experience in program management of pharmaceutical products focused on small molecule drug preclinical and clinical development Knowledge of biotechnology/pharmaceutical preclinical and clinical development processes Track record of successful leadership, management, and development of multi-disciplinary project management teams. Skills / Capabilities Expertise in Microsoft suite (Program, PowerPoint, SharePoint, Word, Excel, Visio, Outlook). Experience with SharePoint and PM tools. Excellent oral and written communication skills, including presentation and facilitation skills, to effectively inform key updates & issues across all levels of the organization. Ability to work independently and successfully in a fast-paced, results-driven, highly accountable environment with large potential impact. Prioritize and manage multiple tasks simultaneously, integrate cross-functional issues and balance competing priorities effectively. Strong analytical, problem solving and critical thinking skills, including an ability to combine attention to detail with a big picture perspective. Available to travel if/when needed. Values and Behaviors: Flagship is an experiment in institutional, entrepreneurial, and innovation practiced in the context of a small company with an insurgent mindset. We are seeking individuals with an entrepreneurial spirit, strong communication skills, and comfort in working in and contributing to a dynamic and cross-functional team environment. At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, we encourage you to apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background. The level of the role will be commensurate with the education and years of experience of the identified candidates. Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

This job posting was last updated on 12/10/2025

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