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GH

Guardant Health

via Workday

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Senior Security Engineer

Anywhere
Full-time
Posted 3/2/2026
Direct Apply
Key Skills:
Kaseya Scripting
PowerShell
Active Directory

Compensation

Salary Range

$111K - 152K a year

Responsibilities

Lead patching and automation efforts for endpoint management using RMM tools.

Requirements

Extensive experience in security engineering, programming, and cloud security required, which the candidate does not demonstrate.

Full Description

Company Description Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visit guardanthealth.com and follow the company on LinkedIn, X (Twitter) and Facebook. Position Summary: The Senior Security Engineer, reporting to the Manager of Security Engineering, will be responsible for building, managing, and operating security tools and services. You will collaborate with product, engineering, IT, compliance, privacy, and your peers on the security teams to assess, adopt/develop, integrate, and innovate existing or new security technologies in order to reduce or eliminate risks before they become security incidents. Essential Duties and Responsibilities: Design, build, and deploy new and existing security solutions. Lead automation efforts to streamline security processes. Develop documentation and runbooks for security tools. Ensure that commercial security tools are optimized, including the use of all relevant features. Identify gaps in the security toolset and work on solutions. Provide guidance to other departments, including engineering and IT teams, on the deployment of security tools. Design and build security metric-focused dashboards and reports. Assist with security operations and threat response to proactively address potential risks. Design and implement proper security tool Identity and Access Management (IAM). Create Responsibility Assignment Matrices (RACIs) for security tools. Mentor and share security best practices with other parts of the organization. Serve as an SME on all topics related to security operations and engineering. Remain current with trends, technologies, security threats, and health care technologies. Required Qualifications: 10+ years of experience in security engineering and/or operations Programming experience using languages such as Python, Go, Ruby, Java, etc. Obsession with creating and maintaining proper, usable documentation. Experience securing cloud (e.g., AWS, Azure, GCP) and IT infrastructure (Linux, Windows, Networks, etc.) Experience building and managing security tools (e.g., SIEM, DLP, EDR, WAF, SSO, identity & access management) Emphasis on DevSecOps mindset Strong experience with integrations and automation in a security context. Demonstrated knowledge of proper engineering principles Proficient in building and managing security solutions in AWS. Strong written and verbal communication skills Ability to work independently and collaboratively Hybrid Work Model: This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients. The annualized base salary ranges for the primary location and any additional locations are listed below. This range does not include benefits or, if applicable, bonus, commission, or equity. Each candidate’s compensation offer will be based on multiple factors including, but not limited to, geography, experience, education, job-related skills, job duties, and business need. Primary Location: Remote-USA-OR Primary Location Base Pay Range: $110,755 - $152,320 Other US Location(s) Base Pay Range: $110,755 - $152,320 If the role is performed in Colorado, the pay range for this job is: $117,270 - $161,280 Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time. Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to Peopleteam@guardanthealth.com A background screening including criminal history is required for this role. GH will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952). Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. All your information will be kept confidential according to EEO guidelines. To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants. Please visit our career page at: http://www.guardanthealth.com/jobs/ If you like wild growth and working with happy, enthusiastic over-achievers, you'll enjoy your career with us! Our Work Experience is the combination of everything that's unique about us: our culture, our core values, our company meetings, our commitment to sustainability, our recognition programs, but most importantly, it's our people. Our employees are self-disciplined, hard working, curious, trustworthy, humble, and truthful. They make choices according to what is best for the team, they live for opportunities to collaborate and make a difference, and they make us the #1 Top Workplace in the area.

This job posting was last updated on 3/2/2026

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