Braveheart Bio

Compensation

Full Description

About us: Braveheart Bio is a Bay Area–based biopharmaceutical company pioneering best-in-class therapies for cardiovascular disease. Our lead program is a next-generation myosin inhibitor, licensed from Hengrui Pharma, being developed to transform the treatment of hypertrophic cardiomyopathy (HCM)—the most common inherited cardiac disease. Currently in Phase 3 clinical development in China for the more common obstructive form of HCM, our candidate has demonstrated a compelling clinical profile that may position it as a best-in-class therapy with meaningful differentiation. With a proven leadership team, a strong financial foundation, and a high-value late-stage asset, Braveheart Bio represents an outstanding opportunity for ambitious, mission-driven professionals to make a tangible impact in a high-profile and rapidly evolving therapeutic area. The role: The Senior Director, Program Management is responsible for strategically driving our lead asset, which is Phase 3-ready, through Phase 3 clinical development, global regulatory submission (NDA), and launch preparedness. You will work closely with the Executive Leadership Team to define the program’s integrated, cross-functional strategy, ensuring alignment, proactive risk mitigation, and disciplined execution across all CMC, Clinical, Regulatory, and Commercial workstreams. This is a highly visible, hands-on position requiring exceptional leadership and a proven ability to manage complex late-stage programs in a fast-paced, resource-constrained startup environment. This leadership role is centered on translating the cross-functional Program Team (PT) strategy into efficient execution. You will be responsible for defining the detailed, integrated development plan; predicting obstacles and planning solutions to achieve program goals; and driving clarity while removing operational barriers for the team. Your influence will be crucial for interfacing with executive management and internal governance, ensuring all stakeholders are aligned on the path forward and that critical program decisions are made and executed efficiently. Key responsibilities: • Work with the leadership team to develop pipeline strategies and build high-performing teams that can deliver defined business solutions • Develop and deliver on project plans to guide programs while managing risk, contingencies and/or corrective actions • Lead and manage the project management function • Define and direct the technical approach to project management • Lead and provide effective project/program leadership of the development team to deliver high-quality projects/programs with clear boundaries and outcomes on time and within budget • Work in partnership with the Leadership Team to develop and implement overall project/program strategy • Align development plans across Regulatory, Clinical, R&D, Pharmacology-Toxicology and CMC • Interface with Regulatory Affairs to develop global regulatory strategy and plans • Provide cross-functional leadership for the strategic planning of integrated development plans for programs, starting at first-in-human through registration • Co-chair cross-functional project/program team meetings to ensure appropriate action plans are created and implemented • Set realistic yet aggressive timeframes for achieving objectives with team buy-in and alignment • Lead cross-functional project/program team(s) to prepare Target Product Profile and global development plan to deliver differentiated products, leveraging the scientific and medical leadership of the Leadership Team • Define and implement a communication strategy/plan for the program that supports the most effective team empowerment and progress • Act as an appropriate role model/coach/mentor to facilitate the success and development of individuals within the teams and the team as a whole Required experience & skills: • Minimum of a Bachelor’s degree • Minimum of 12 years of relevant experience • Proven track record of experience in drug development, especially with project/program leadership of cross-functional teams • Demonstrated experience planning, managing and completing one or more large, complex project with teams of 30+ individuals, 18+ month duration and implementation cost of $20M+, engaging varied functional stakeholders • Experience leading programs through the complexity of Phase 3 and regulatory submission readiness • A strong understanding of the biotech drug development process and regulations • Strong written and verbal communication skills with a collaborative, team-oriented approach • Ability to thrive in a fast-paced, dynamic environment and remain comfortable with change and ambiguity • Flexible, proactive, and hands-on mindset with a roll-up-your-sleeves, can-do attitude Preferred experience & skills: • Advanced degree (MBA, MS, PhD) will be considered in lieu of industry work experience • PMP certification • Expertise gained from working directly in an R&D functional domain (e.g., Research, Clinical, CMC, or Regulatory Affairs), combined with global team exposure and prior Project/Program Leadership experience, is highly desirable We are an equal opportunity employer. We are committed to inclusion and diversity, and we do not discriminate on the basis of race, gender, religion, gender, sexual orientation, age, color, marital status, veteran status, disability status, national origin, or any characteristic protected under applicable law.