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BC

Black Canyon Consulting

via Greenhouse

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Senior Software Developer C++ (Program Principal Engineer )

Bethesda, Maryland
Full-time
Posted 2/12/2026
Direct Apply
Key Skills:
Java
SQL
C#

Compensation

Salary Range

$120K - 200K a year

Responsibilities

Develop and maintain bioinformatics software and data infrastructure for NCBI.

Requirements

Requires 5+ years of experience with large data handling, C++ proficiency, and bioinformatics experience.

Full Description

Overview Black Canyon Consulting (BCC) is searching for a Senior C++ Software Developer to support our work for the National Center for Biotechnology Information (NCBI) at the National Library of Medicine (NLM), an institute of the National Institutes of Health. This opportunity is full time and onsite at the NIH-NCBI in Bethesda, MD and/or remote work. NCBI, the National Center for Biotechnology Information, the nation’s premier biomedical resource, is seeking a software developer to help deliver biological sequence annotation and data curation infrastructure for the nation’s foremost sequence and biomedical literature repositories. Sites at NCBI, a part of the National Library of Medicine (NLM) at the National Institutes of Health (NIH), see four million daily users searching for gene sequence data, biomedical journal citations, and a wide array of other information that directly impacts biomedical research and public health. NCBI’s annotation pipelines not only serve these diverse expert communities – they actually drive new life sciences discoveries, ranging from medical health (viruses and pandemics, genetic diseases, cancer) to public health (food safety monitoring, antimicrobial resistance, viral outbreaks), to basic research topics in computational biology, bioinformatics and microbial diversity, and many more. Duties & Responsibilities: Responsible for the development, implementation, testing, and continued maintenance of NCBI bioinformatics software and information retrieval systems Work with a diverse group of scientists, bioinformaticians and other developers across the center to implement efficient bioinformatics algorithms Learn new technologies, keep up with internal systems, and share your knowledge with the team Required qualifications: 5+ years of experience handling large amounts of data or working in a distributed computing environment Programming experience in a Linux environment Proficiency in C++ Experience with MS SQL server and relational database design and optimization Fluency in some scripting languages such as BASH, csh, Perl, or Python Preferred qualifications: 5+ years of working with genetic and biological data Proficiency in Python and/or JavaScript and familiarity with their associated ecosystems Experience with MongoDB or other NoSQL database technology Experience with Docker or other containerization mechanisms Experience with CI/CD pipelines, unit testing, integration and regression testing Experience using GitHub Experience with Cloud technologies a strong plus We attract the best people in the business with our competitive benefits package that includes medical, dental and vision coverage, 401k plan with employer contribution, paid holidays, vacation, and tuition reimbursement. If you enjoy being a part of a high performing, professional service and technology focused organization, please apply today!

This job posting was last updated on 2/18/2026

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