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AX

Axle

via Greenhouse

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Senior Program Manager

Rockville, Maryland
Full-time
Posted 2/24/2026
Direct Apply
Key Skills:
Program Management
Biomedical Informatics
IT Engineering
Data Science
Contract Oversight

Compensation

Salary Range

$120K - 150K a year

Responsibilities

Lead and oversee a multidisciplinary team managing biomedical informatics, IT engineering, and data science projects for NIH with contract and compliance oversight.

Requirements

10+ years managing complex federal biomedical IT projects with leadership of technical teams and a relevant bachelor's degree.

Full Description

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations around the globe. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH). Benefits: 100% Medical, Dental & Vision Coverage for Employees Paid Time Off (Including Holidays) Employee Referral Bonus 401K Match Tuition reimbursement and professional development opportunities Flexible Spending Accounts: Healthcare (FSA) Parking Reimbursement Account (PRK) Dependent Care Assistant Program (DCAP) Transportation Reimbursement Account (TRN) Position Overview Axle is seeking a Senior Program Manager to provide overall leadership and management for a multidisciplinary team supporting the National Institutes of Health (NIH). This role oversees program execution across biomedical informatics, IT engineering, data science, and operational support functions. The Program Manager will ensure successful contract performance, alignment with NIH objectives, and delivery of high-quality services supporting both basic and clinical research enterprises. This opportunity supports a blended team providing PMO leadership, IT engineering and sustainment, biomedical informatics and data science, as well as policy, process, communications, and training functions. The work enables both NIH basic research and the NIH clinical research enterprise. Key Responsibilities Provide overall program leadership and contract oversight. Serve as the primary point of contact with the NIH Contracting Officer’s Representative (COR). Oversee task execution across biomedical informatics, IT engineering, and operational support functions. Manage staffing, performance, deliverables, timelines, and risk mitigation. Ensure compliance with federal requirements, reporting standards, and quality controls. Lead strategic planning, performance monitoring, and continuous improvement initiatives. Facilitate communication across stakeholders, technical teams, and NIH leadership. Qualifications 10 years Ten (10) years of progressive, successful experience managing complex projects and a Bachelor's degree in Computer Science, Information Systems, Engineering, Business, or other related medical, scientific, or technical discipline. Experience managing federal health or biomedical IT contracts. Demonstrated leadership of multidisciplinary technical teams. Strong understanding of biomedical research, informatics, or data science environments preferred. Excellent communication and stakeholder engagement skills. Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed. The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate. Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location. Salary Range $120,000 - $150,000 USD

This job posting was last updated on 2/27/2026

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