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AS

AstraZeneca

via Workday

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Executive Director, Portfolio Strategy & Business Development - OBU Strategy

Gaithersburg, Maryland
Full-time
Posted 12/5/2025
Direct Apply
Key Skills:
Oncology strategy
Pharmaceutical pipeline strategy
Market assessment
Competitor analysis
Forecasting
Data analysis
Team leadership
Stakeholder management
Business development
Clinical trial design

Compensation

Salary Range

$270K - 405K a year

Responsibilities

Lead and implement oncology business unit strategies, manage portfolio initiatives, engage senior leaders, oversee team members, and collaborate across functions to drive growth and innovation.

Requirements

Bachelor's degree with 15+ years in oncology or related pharmaceutical industry experience, strong scientific and strategic skills, leadership experience, and ability to influence senior stakeholders.

Full Description

Introduction to role: Drive innovation and impact at AstraZeneca by leading strategy for our industry-leading oncology pipeline. Collaborate with R&D and the Oncology Business Unit (OBU) to shape and deliver cutting-edge therapies that improve patient outcomes and bring us closer to eradicating cancer. Working with a team of experts across Oncology R&D and the Oncology Business Unit, responsible for creating and implementing strategies to deliver an industry-leading and innovative oncology pipeline that improves patient care and outcomes. Strategies will be multi-brand or brand agnostic and built through analyses, insights, innovative thinking and cross-functional teamwork. An opportunity for a motivated, collaborative data-driven leader to help AstraZeneca one day eradicate cancer as a cause of death. The role includes people management responsibilities, overseeing a high-performing team and fostering a culture of collaboration, maintaining high-performance and accountability. Accountabilities: Leads the development and implementation of Business Unit therapy area, multi-brand or brand-agnostic strategies that integrate into one company-wide oncology strategy built with counterparts in global franchises and oncology R&D Drives portfolio strategic initiatives that enhance AZ’s competitiveness and deliver sustainable growth Frequently engages with C-Suite level leaders (SET and SET-1) to provide disciplined insights-driven valuations and strategies Drives clarity and consistency across priority business processes in major governance forums. These include investment decisions, TA Strategy/Portfolio reviews and long range plans across the specific tumour portfolios Engages with Finance VPs to ensure robust assessment of value in annual impairment review (key audit process) Leads the portfolio team in delivery of the commercial analysis, business development valuations, forecasting, market research and insight generation to shape and deliver OBU priorities: R&D decisions, supply planning and TA scenario analysis – including leadership of other team members working across the OBU Strategy team. You will work closely with the tumor area heads in OBU Strategy to do this. Understanding and communication of complex study design, TPPs, CDP’s, combination approaches, competition, pricing, prioritization, and decision making considerations expected in the context of our competitors’ strategies Managing large investment requests and business development opportunity assessments with extreme confidentiality, quality and rigor for consistency in approach Influence with and without authority a large number of senior stakeholders (SET, SET-1, SET-2) across OBU and ORD and criss-crossing tumour and asset alignment meetings Monitor market trends, competitive dynamics, and emerging science to inform strategic planning and business development priorities. Support Head of OBU Strategy to coordinate, oversee and integrate all tumor into one portfolio strategy Collaborate closely with Corporate Development, Finance, and R&D to support deal negotiations and integration planning. Guide and direct team members at the director and associate director level Maintain trusted partnering, credibility and collaboration with clinical, commercial and strategy leaders Essential Skills & Experience: Bachelor's degree 15 years of relevant industry experience (or MBA/PhD with 10 years of relevant experience) Extensive experience in oncology +/- haematology Strong consultative and communication skills A strong scientific background and strategic analytical skills Industry or consulting experience in pharmaceutical pipeline strategy (market assessment, competitor analysis, forecasting) Excellent analysis and fact-based decision-making Experience with data and/or a science research/bio-pharmaceutical environment Motivated by working in a fast-paced field with clear societal impact Understanding of general business and core marketing principles and application to future healthcare market challenges Familiar with the oncology drug development process and necessary strategic and commercial touch points Prior experience managing direct reports Able to influence without authority and establish and maintain credibility with senior audiences Resourceful, motivated, decisive and proactive; must be able to manage multiple priorities in a fast-growing organization Attention to detail while also a big picture thinker & communicator A critical thinker with experience of identifying and driving key projects and providing researched, verified, relevant information to leaders. Desirable Skills & Experience: MBA or PhD with 10 years of relevant experience Experience of setting up short- and long-term strategic plans Understanding of clinical data and clinical trial design Experience in at least two major geographies (e.g. US, EU, Japan, China) Experience in cell therapy and/or radioconjugates Thorough understanding of regulatory and pricing dynamics in major markets Comfortable with AI and utilizing AI to support ethical and accurate analyses of data The annual base pay for this position ranges from $270,222 - $405,332. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. Date Posted 05-Dec-2025 Closing Date 19-Dec-2025 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.

This job posting was last updated on 12/9/2025

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