$150K - 250K a year
Lead and optimize integrated clinical program strategies, manage cross-functional teams and external partnerships, and ensure alignment and execution of drug development plans.
PhD or equivalent with 8+ years industry experience in drug development, oncology and clinical operations expertise, advanced project management and leadership skills.
About the Company Ascentage Pharma (Nasdaq: AAPG and HKEX: 6855) is a global, clinical-stage biotechnology company developing novel therapies for cancer and other diseases. Ascentage Pharma is proud of its collaborative and supportive culture, unified by a shared desire to develop therapeutics that will have a positive impact on patients’ lives. Ascentage Pharma is a dynamic and fast-paced organization that has been responsive to the needs of individual employees throughout its history. The company is defined by a shared understanding that it succeeds in advancing its mission only as each experiences success in their role. Leveraging our robust internal research and development capabilities, we have built a portfolio of global intellectual property rights. We have also established global collaboration relationships with leading biotechnology and pharmaceutical companies, such as AstraZeneca, Innovent, Merck, and Pfizer, and research and development relationships with leading research institutions, such as Dana-Farber Cancer Institute, Mayo Clinic, MD Anderson Cancer Center, National Cancer Institute and the University of Michigan. We are a leader in global innovation with a portfolio of more than U.S. and international patents and more than U.S. and international pending applications. We have assembled a talented, global team with experience in the research and development of innovative drugs, as well as commercial manufacturing, sales, and marketing. Our success is shaped by this global team of close to six hundred employees across the United States, Europe, Australia, and China. About the Role The Sr. Director, Clinical Program Manager will have primary responsibility for the development and optimization of the integrated program strategy, providing leadership in collaboration with the program lead. The role involves coordination of the planning and tracking of activities such as drug supply, formulation development, preclinical work for indication expansion and patient selection, and supportive clinical pharmacology and toxicology studies. The role also involves significant contributions to organizational initiatives and external partnerships to ensure cross-functional alignment and execution of integrated development plans. Responsibilities • Drive the development and optimization of the integrated program strategy • Provide, in collaboration with the Clinical Program Leader, strategic leadership to the Clinical Program Team for the clinical development of therapeutics in the pipeline • Drive, together with the Clinical Program Leader, the program strategy by planning and tracking activities, such as drug supply and formulation development, preclinical work for indication expansion and patient selection strategies, supportive clinical pharmacology and toxicology studies • Lead and contribute to organizational initiatives and external partnerships • Leads and contributes to task forces, ,sub-teams or broader cross-functional organizational initiatives • Manage external partnerships with other Pharmaceutical/Biotech companies or academic institutions • Achieve organizational alignment and seamless execution of the integrated development plan • Accountable for the cross-functional alignment and organizational support of the integrated development plan by facilitating internal and external stakeholder management • Drive the team's objective setting, prioritization, and tracking,g ensuring adherence to the development strategy and operational plan • Assure ongoing optimization of program timelines and resource requirements • Lead risk management and contingency planning, and monitor the implementation of risk mitigation strategies at the program level • Enable high-performing teams and associates • Foster team building, interactions, and collaboration, striving for high-performing clinical program teams • Develop team members through coaching and mentoring • Drive issue identification and resolution in alignment with the concerned line functions and the program team • Ensure effective, proactive, and open communications within and across the program team to achieve transparency and clarity of program goals, progress, and issues • Deputized as the Clinical Program Leader and spokesperson for the program team Qualifications & Educational Requirements • Ph.D., PharmD in Life Sciences or MBA with a bachelor's degree, or equivalent experience in life science, and at minimum 8 years’ industry experience in drug development is Required • Strong scientific background in Biology, Chemistry or Pharmaceutical Sciences • Several years of multi- and cross-functional leadership experience in international and multidisciplinary drug development teams • Expert knowledge of the drug development process, incl. advanced knowledge of regulatory and business requirements. Oncology and clinical operations experience is a must. • Advanced project management skills, capable of managing multiple projects concerning priorities and self-management • Strong interpersonal and communication skills for bridging between scientific and business participants, for negotiating timelines, and for effective international collaboration. Strong verbal communication and an expert in written communications Culture At Ascentage Pharma, we strive to create a culture based on personal and professional growth and opportunity, focusing on these principles: • Establish a collaborative, energized, and fun work environment where people are empowered and supported in achieving their career goals. Working at Ascentage Pharma allows you to balance your priorities. • Create a diverse and multi-disciplinary workforce at all levels • Cultivate dedicated, talented, and entrepreneurial people who are passionate about achieving excellence in all they do every day, with a shared commitment to science and to the patients we serve Compensation and Benefits Ascentage Pharma offers an extremely competitive compensation package, including an annual bonus. Ascentage Pharma also offers: • We offer exceptional Medical, Dental, and Vision plans for employees and families • Employee paid life, STD & LTD, as well as a comprehensive insurance package with spouse life Insurance, Critical Illness, and Accident Insurance • 401K with an immediate and generous company match • Liberal paid time off • Flexible schedules for staff and an employee assistance program Ascentage Pharma is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community, and embracing diversity and inclusion. It is Ascentage Pharma's policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, marital status, status as a protected veteran, or any other legally protected group status.
This job posting was last updated on 9/26/2025