$170K - 190K a year
As a Software Architect, you will assess the current architecture and identify improvements while defining system architecture and integration patterns. You will also mentor engineers and guide technical decisions across the team.
The role requires 10+ years of software engineering experience, with deep expertise in AWS services and strong knowledge of Python. Experience in designing data-intensive systems and handling PHI is essential.
Based in San Francisco, Arine is a rapidly growing healthcare technology and clinical services company with a mission to ensure individuals receive the safest and most effective treatments for their unique and evolving healthcare needs. Frequently, medications cause more harm than good. Incorrect drugs and doses costs the US healthcare system over $528 billion in waste, avoidable harm, and hospitalizations each year. Arine is redefining what excellent healthcare looks like by solving these issues through our software platform (SaaS). We combine cutting edge data science, machine learning, AI, and deep clinical expertise to introduce a patient-centric view to medication management, and develop and deliver personalized care plans on a massive scale for patients and their care teams. Arine is committed to improving the lives and health of complex patients that have an outsized impact on healthcare costs and have traditionally been difficult to identify and address. These patients face numerous challenges including complicated prescribing issues across multiple medications and providers, medication challenges with many chronic diseases, and patient issues with access to care. Backed by leading healthcare investors and collaborating with top healthcare organizations and providers, we deliver recommendations and facilitate clinical interventions that lead to significant, measurable health improvements for patients and cost savings for customers. Why is Arine a Great Place to Work?: Outstanding Team and Culture - Our shared mission unites and motivates us to do our best work. We have a relentless passion and commitment to the innovation required to be the market leader in medication intelligence. Making a Proven Difference in Healthcare - We are saving patient lives, and enabling individuals to experience improved health outcomes, including significant reductions in hospitalizations and cost of care. Market Opportunity - Arine is backed by leading healthcare investors and was founded to tackle one of the largest healthcare problems today. Non-optimized medications therapies which cost the US 275,000 lives and $528 billion annually. Dramatic Growth - Arine is managing more than 18 million lives across prominent health plans after only 4 years in the market, and was ranked 236 on the 2024 Inc. 5000 list and was named the 5th fastest-growing company in the AI category. The Role: As our first dedicated Software Architect, you will partner closely with the VP of Engineering, product, and engineering teams to chart the next phase of our platform’s evolution. You’ll evaluate our current AWS Lambda- and cron-driven system, rationalize our database usage (DynamoDB and RDS), define service and integration patterns, and set standards for both the React front-end and the underlying Python Lambda services. This is a hands-on architecture role: you will spend time in the code, guide design decisions, mentor engineers, and set the technical direction. What You’ll Do: Assess the current architecture (React front-end, Python Lambdas, schedule-driven services, DynamoDB, RDS, Snowflake, UI) and identify short-term fixes and long-term improvements. Define and document system architecture, integration patterns, and data flows across services. Rationalize use of DynamoDB vs RDS; create consistent standards for schema design, indexing, and access patterns. Establish best practices for both real-time front-end-to-Lambda interactions and schedule-driven service workflows. Design systems with PHI (Protected Health Information) security, privacy, and compliance as a first-class concern. Collaborate with security/compliance teams to ensure HIPAA and SOC 2 readiness. Mentor engineers and influence technical decisions across the team. Guide build-vs-buy tradeoffs as we scale. What We’re Looking For: 10+ years of experience in software engineering, with at least 3+ years in a senior architect or staff/principal engineer role. Deep expertise with AWS services (Lambda, API Gateway, DynamoDB, RDS, S3, Step Functions, EventBridge, CloudFormation/Terraform). Strong knowledge of Python and experience in modernizing Lambda-based systems. Experience with front-end to serverless back-end architectures (React → Lambda → data layer). Experience designing data-intensive systems and integrating with Snowflake or similar warehouses. Solid background in distributed systems, event-driven design, and API architectures. Strong database fundamentals: relational design, indexing, DynamoDB access patterns, and data modeling tradeoffs. Experience designing and operating systems that securely handle PHI or other regulated data. Ability to balance pragmatic short-term fixes with long-term scalable design. Excellent communication and documentation skills; comfortable influencing at all levels of the org. Startup experience preferred; thrives in fast-paced, evolving environments. Bonus Skills: Hands-on experience with modern React frameworks (Next.js, Vite). Experience with observability (CloudWatch, Datadog, OpenTelemetry). Background in regulated environments (healthcare, fintech) with SOC2/HIPAA compliance. Knowledge of data governance, lineage, or metadata systems. Why Join Arine?: Mission-driven company improving healthcare outcomes at scale Collaborative culture emphasizing mentorship, growth, and technical excellence Modern tech stack with opportunities to influence architecture and direction Competitive compensation, equity, and comprehensive benefits Remote Work Requirements: An established private work area that ensures information privacy A stable high-speed internet connection for remote work This role is remote, but you will be required to come to on-site meetings multiple times per year. This may be in the interview process, onboarding, and team meetings Perks: Joining Arine offers you a dynamic role and the opportunity to contribute to the company's growth and shape its future. You'll have unparalleled learning and growth prospects, collaborating closely with experienced Clinicians, Engineers, Software Architects, and Digital Health Entrepreneurs. The posted range represents the expected salary for this position and does not include any other potential components of the compensation package, benefits, and perks. Ultimately, the final pay decision will consider factors such as your experience, job level, location, and other relevant job-related criteria. The salary range for this position is: $170,000-190,000/year. Job Requirements: Ability to pass a background check Must live in and be eligible to work in the United States Information Security Roles and Responsibilities: All staff at Arine are expected to be part of its Information Security Management Program and undergo periodic training on Information Security Awareness and HIPAA guidelines. Each user is responsible to maintain a secure working environment and follow all policies and procedures. Upon hire, each person is assigned and must complete trainings before access is granted for their specific role within Arine. Arine is an equal opportunity employer. We are committed to creating a diverse and inclusive workplace where all employees are treated with fairness and respect. We do not discriminate on the basis of race, ethnicity, color, religion, gender, sexual orientation, age, disability, or any other legally protected status. Our hiring decisions and employment practices are based solely on qualifications, merit, and business needs. We encourage individuals from all backgrounds to apply and join us in our mission. Check our website at https://www.arine.io. This is a unique opportunity to join a growing start-up revolutionizing the healthcare industry! Job Offers: Arine uses the arine.io domain and email addresses for all official communications. If you received communication from any other domain, please consider it spam. Note to Recruitment Agencies: We appreciate your interest in finding talent for Arine, but please be advised that we do not accept unsolicited resumes from recruitment agencies. All resumes submitted to Arine without a prior written agreement in place will be considered property of Arine, and no fee will be paid in the event of a hire. Thank you for your understanding.
This job posting was last updated on 10/8/2025